Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Formulary > Cardiac drugs > Flashcards

Cardiac drugs Flashcards

(63 cards)

Start Studying
1
Q

Furosemide: Action

A

Loop diuretic

GABA-A blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Furosemide: Contraindications (2)

A

Severe hypokalaemia

Hyponatraemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Furosemide: Side Effects (3)

A

Hyperglycaemia
Hypokalaemia
Ototoxic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Furosemide: Indications (3)

A

Oedema
Hypertension
Heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Bendroflumethiazide: Action

A

Thiazide diuretic

Inhibit Na reabsorption in the distal convoluted tubule

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Bendroflumethiazide: Indications (2)

A

Oedema

Hypertension

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Bendroflumethiazide: Side Effects (6)

A 
Hypokalaemia
Hyponatraemia
Hypomagnesaemia 
Hypercalcaemia
Hyperglycaemia
Gout
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Spironolactone: Action

A

Potassium sparing diuretic

Inhibit mineralocorticoids => reduce Na and water reabsorption => limit potassium secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Spironolactone: Indications (3)

A

Oedema
Hypertension
Congestive heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Spironolactone: Contraindications (2)

A

Addison’s

Hyperkalaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Spironolactone: Side Effects (2)

A

Hyperkalaemia

Gynaecomastia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Atenolol: Action

A

Beta blocker

Inhibit adrenaline => reduce heart rate, force of contraction, glycogen breakdown and bronchoconstriction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Atenolol: Indications (3)

A

Hypertension
Angina
Arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Atenolol: Contraindications (3)

A

Asthma
Bradycardia
Metabolic acidosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Atenolol: Side Effects (3)

A

Cold extremities
Headache
Sleep disturbances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Atenolol: Interaction

A

Do not use with verapamil/diltiazem

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Diltiazem: Action

A

Calcium antagonist

Depress AV node conduction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Diltiazem: Contraindications (2)

A

LVF

2nd and 3rd degree heart block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Diltiazem: Side Effects (3)

A

Palpitation
Dizziness
Hot flush

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Diltiazem: Interaction

A

Do not use with B blockers (heart failure and bradycardia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Ramipril: Action

A

ACE inhibitor

Reduce angiotensin II => smooth muscle relaxation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Ramipril: Indications (4)

A

Hypertension
Heart failure
DM (prevent MI)
Nephropathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Ramipril: Side Effects (3)

A

Dry cough
Angioedema
Hyperkalaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Ramipril: Interaction

A

Caution with potassium elevating drugs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Losartan: Action
AT1 blocker | Reduce organ response to angiotensin II => reduce peripheral resistance
26
Losartan: Indications (3)
Hypertension Heart failure Diabetic nephropathy
27
Losartan: Contraindications (3)
Renal artery stenosis AKI Pregnancy
28
Losartan: Side Effects (3)
Hypotension (esp w 1st dose) Hyperkalaemia Renal failure
29
Isosorbide Mononitrate: Action
Stimulate guancyclate cyclase => reduce intracellular calcium => relax smooth muscle
30
Isosorbide Mononitrate: Contraindications (3)
Hypotension Hypovolaemia Aortic stenosis
31
Isosorbide Mononitrate: Side Effect
Postural hypotension
32
Digoxin: Action
Cardiac glycoside | Inhibit NaK ATPase => increase intracellular calcium => stronger contraction and reduced heart rate
33
Digoxin: Indications (2)
Heart failure | Atrial fibrillation/flutter
34
Digoxin: Contraindications (3)
Complete heart block Secondary AV block Ventricular tachycardia/fibrillation
35
Digoxin: Side Effects (3)
Rash Dizziness Blurred/yellow vision
36
Digoxin: Interaction
Increased toxicity with amiodarone, CCB, spironolactone and loop/thiazide diuretics
37
Amiodarone: Action
Class III anti-dysrhythmic | Prolongs repolarisation => increase refractory period and decrease conduction
38
Amiodarone: Indications (2)
Atrial fibrillation/flutter | Tachyarrhythmias
39
Amiodarone: Contraindications (2)
SA heart block | Thyroid dysfunction
40
Amiodarone: Side Effects (4)
Jaundice Pulmonary toxicity Grey skin Thyroid dysfunction
41
Amiodarone: Interaction
Increases concentration of anticoagulants, phenytoin and digoxin
42
Aspirin: Action
Anti-platelet | COX-1+2 inhibitor => block thromboxane production => prevent platelet aggregation
43
Aspirin: Side Effects (2)
GI irritation/ haemorrhage | Tinnitus
44
Clopidogrel: Action
Anti-platelet | ADP inhibitor on platelet => stop platelet activation and fibrin cross-linking
45
Clopidogrel: Side Effects (2)
Bleeding disorder | Thrombocytopenia
46
Clopidogrel: Interaction
Metabolised by P450 enzymes
47
Streptokinase: Action
Fibrinolytic | Produce plasmin to promote fibrin breakdown
48
Streptokinase: Contraindications (2)
Increased bleeding risk | Previous streptokinase treatment
49
Streptokinase: Side Effects (4)
Bruising Bleeding Cardiac arrest Arrhythmia
50
Streptokinase: Interaction
ACEi increase risk of anaphylaxis
51
Enoxaparin: Action
Low molecular weight heparin | Bind to antithrombin II to inactivate factor Xa and thrombin
52
Enoxaparin: Contraindications (3)
Haemophilia Thrombocytopenia Severe hypertension
53
Enoxaparin: Side Effects (2)
Haemorrhage | Thrombocytopenia
54
Rivaroxoban: Action
Factor Xa inhibitor => inhibit thrombin formation
55
Rivaroxoban: Side Effects (6)
``` Hypotension Renal impairment Dry mouth Pruritus Jaundice Angioedema ```
56
Rivaroxoban: Interaction
Partially metabolised by P450
57
Simvastatin: Action
Inhibit HMG CoA reductase => reduce endogenous cholesterol production
58
Simvastatin: Contraindication
Pregnancy
59
Simvastatin: Side Effects (4)
Myalgia Myositis Myopathy Jaundice
60
Simvastatin: Interaction
Metabolism reduced by P450 inhibitors (amiodarone)
61
Warfarin: Action
Vitamin K inhibitor => reduce factors II, VII, IX and X
62
Warfarin: Side Effects (5)
``` Haemorrhage Hepatic dysfunction Pancreatitis Purpura Rash ```
63
Warfarin: Interaction
Avoid clopidogrel | Metabolised by the P450 system

Formulary (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions