Cardio

Question 1

AntiHTN for blacks

Answer 1

CCBs

thiazide diuretics

Question 2

Angioedema

Answer 2

Edema of dermis and mucosa (lips)
Due to insufficient Bradykinin degradation by ACE
Cause by ACEi

Question 3

Thiazide diuretic MOA

Answer 3

Work in DCT
inhibit an-cl symporter
5% an reabsorption

Question 4

Diuretic effect on heart

Answer 4

Decrease preload by decreased venous return

Relieve edema

Question 5

Thiazide diuretic drugs

Answer 5

Chlorthalidone
Indapamide
Hydrochlorothiazide

Question 6

Carbonic anhydride inhibitors MOA

Answer 6

Inhibit NaHCO3 reabsorption in PCT

TX glaucoma chf edema and altitude sickness

Question 7

Carbonic anhydrase inhibitor drug

Answer 7

Acetazolamide

Question 8

Loop diuretic MOA

Answer 8

Inhibit Na-K-Cl2 co transporter in thick ascending limb
25% Na reabsorption
Tx severe edema, chf, hypercalcemia and renal disease

Question 9

Loop diuretic drug

Answer 9

Furosemide

NSAIDs and lithium decrease effectiveness

Question 10

K sparing diuretics MOA

Answer 10

Inhibit Na influx in CT and distal tubule

1-2% Na reabsorption

Question 11

K sparing diuretic drugs

Answer 11

Spironolactone

Triamterene

Question 12

ACEi MOA

Answer 12

ACE inhibition and prevent bradykinin degradation for vasodilation

Question 13

ACEi indication

Answer 13

HTN
MI
HF
diabetes

Question 14

ACEi side effects

Answer 14

First dose hypotension
Cough
Angioedema

Question 15

ACEi contraindications

Answer 15

Preg cat x
Hyperperfusion
Use caution with NSAIDs

Question 16

ACEi drugs

Answer 16

Enalapril
Isinopril
Quinapril

Question 17

ARB MOA

Answer 17

Block type 1 ang II receptors

Decrease pre and after load, inhibits cardiac remodeling, promotes Na excretion, downregulates syp adrenergic activity

Question 18

ARB drugs

Answer 18

Losartan

Valsartan

Question 19

CCB drugs

Answer 19

Dihyrdopiridines
Verapamil
Diltiazem

Question 20

CCB MOA

Answer 20

Block Ca inflict into l type Ca channels in heart
Vascular Smooth muscle vasodilation
Decrease after load and contractility

Question 21

HTN drugs

Answer 21

ACEi
ARB
Beta blockers
CCBs
thiazide diuretics

Question 22

CCB adverse effects

Answer 22

Hypotension
Peripheral edema
Headache

Question 23

Beta blocker indications

Answer 23

HTN to decrease CO
Angina and MI to inhibit remodeling
Arrhythmia: increases conduction velocity and SA node automaticity

Question 24

Beta blocker contraindications

Answer 24

Asthma
AV node block
Sinus bradycardia
Unstable LV HF

Question 25

Beta blocker drugs

Answer 25

``` Metoprolol Propanelol Carvedilol Atenolol Isosorbide ```

Question 26

Beta blocker MOA

Answer 26

Inhibit symp stimulation Prevent NE binding Decrease AP propagation

Question 27

Beta blockers used in CHF

Answer 27

Metoprolol | Carvedilol

Question 28

NO fxn on CV

Answer 28

``` Vasodilation Decrease pre and after load Decrease oxygen demand on heart Antithrombotic Anti inflammatory ```

Question 29

Anti arrhythmic classes

Answer 29

Class 1 sodium block phase 0 Class 2 beta Class 3 potassium block phase 3 Class 4 calcium block phase 4

Question 30

Quinidine

Answer 30

Class 1a anti arrhythmic | For SVT

Question 31

Lidocaine

Answer 31

Class 1b anti arrhythmic | For ischemic VA

Question 32

Flecainide

Answer 32

Class 1c anti arrhythmic Stop PVC, tx SVT. Not to be used in HF Pro arrhythmic

Question 33

Sotalol

Answer 33

Class 3 anti arrhythmic | For VT, contraindicated in asthma