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Theraputics > CARDIO Formulary (cad & hf) > Flashcards

CARDIO Formulary (cad & hf) Flashcards

(150 cards)

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1
Q

Non-DHP CCB

A

diltiazem, verapamil

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2
Q

Diltiazem brand name

A

Cardizem, Tiazac

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3
Q

Diltiazem doses

A

IR- 80-120 mg TID
XR- 180-360mg QD

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4
Q

Diltiazem AEs

A

Reduced myocardial contractility (V>D), AV/SA nodal conduction disturbances, bradycardia, AV block, Hypotension, HA, flushing, Constipation (V>D)

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5
Q

Diltiazem Monitoring

A

goal hr, constipation, av nodal disturbances

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6
Q

verapamil brand

A

Verelen, Calan, Isoptin

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7
Q

verapamil dosing

A

ir- 60-90mg TID or QID
sr- 240mg qd

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8
Q

verapamil AEs

A

Reduced myocardial contractility (V>D), AV/SA nodal conduction disturbances, bradycardia, AV block, Hypotension, HA, flushing, Constipation (V>D)

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9
Q

verapamil monitoring

A

goal hr, constipation, av nodal disturbances

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10
Q

DHP CCB

A

amlodipine, felodipine ER, nifedipine XL
nifedipine

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11
Q

Amlodipine brand

A

Norvasc

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12
Q

Amlodipine doses

A

5-10 mg qd

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13
Q

amlodipine AEs

A

Hypotension, flushing, HA, dizziness, PERIPHERAL
EDEMA (arteriole vasodilation), reduce myocardial
contractility, reflex adrenergic activation

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14
Q

amlodipine monitoring

A

blood pressure, HR, edema

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15
Q

felodipine ER brand

A

Plendil

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16
Q

felodipine ER doses

A

5-10mg qd

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17
Q

felodipine ER AEs

A

Hypotension, flushing, HA, dizziness, PERIPHERAL
EDEMA (arteriole vasodilation), reduce myocardial
contractility, reflex adrenergic activation

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18
Q

felodipine ER monitoring

A

blood pressure, HR, edema

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19
Q

nifedipine XL
nifedipine brand

A

Procardia-XL

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20
Q

nifedipine XL
nifedipine doses

A

30-60 mg qd
10-20mg tid

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21
Q

nifedipine XL
nifedipine AEs

A

Hypotension, flushing, HA, dizziness, PERIPHERAL
EDEMA (arteriole vasodilation), reduced myocardial
contractility, reflex adrenergic activation

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22
Q

nifedipine XL
nifedipine monitoring

A

blood pressure, HR, edema

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23
Q

Nitrates

A

isosorbide mononitrate
isosorbide dinitrate
nitroglycerin
(SL, patch, IV)

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24
Q

nitroglycerin
(SL, patch, IV) brands

A

Nitrostat (SL tab), Nitrolingual (spray),
Nitro-Dur (patch), Nitro-Bid (ung)

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25
nitroglycerin (SL, patch, IV) doses
300-600 mcg SL tab acutely 2.5-26 mg BID to QID chronic 0.4 mg/spray acutely 5-20 mcg/min IV acutely 0.2-0.8 mg/hr patch (on 12h, off 12h)
26
nitroglycerin (SL, patch, IV) AEs
Headache (throbbing, pulsating), hypotension, lightheadedness, dizziness, facial flushing, reflex tachycardia
27
nitroglycerin (SL, patch, IV) monitoring
Blood pressure (hypotension), HR (tachycardia), diary that lists # of NG doses used per week, how many episodes of chest pain encountered, do not use with PDEI, use APAP for HA
28
isosorbide mononitrate brand
Imdur
29
isosorbide mononitrate doses
ir- 10-20mg bid er- 30-240mg qd
30
isosorbide mononitrate AEs
Headache (throbbing, pulsating), hypotension, lightheadedness, dizziness, facial flushing, reflex tachycardia
31
isosorbide mononitrate monitoring
Blood pressure (hypotension), HR (tachycardia), diary that lists # of NG doses used per week, how many episodes of chest pain encountered, do not use with PDEI, use APAP for HA
32
isosorbide dinitrate brand
isordil
33
isosorbide dinitrate doses
ir- 5-40mg bid to tid er/sr- 40-80mg qd
34
isosorbide dinitrate AEs
Headache (throbbing, pulsating), hypotension, lightheadedness, dizziness, facial flushing, reflex tachycardia
35
isosorbide dinitrate monitoring
Blood pressure (hypotension), HR (tachycardia), diary that lists # of NG doses used per week, how many episodes of chest pain encountered, do not use with PDEI, use APAP for HA
36
b1 selective beta blockers
atenolol, bisprolol, metroprolol succinate, nebivolol
37
b1 selective and non-selective beta blockers AEs
Bradycardia, sinus arrest, AV block, reduced LVEF (b/c decreased contractility), fatigue, depression, nightmares, sexual dysfunction, intensify insulin- induced hypoglycemia, peripheral vascular complication, B-blocker withdrawal syndrome (causes angina), bronchoconstriction (non- selective only)
38
atenolol brand
tenormin
39
atenolol doses
50-100mg qd
40
b1 selective and non-selective beta blockers monitoring
Goal HR (rest: 50-60 bpm, exercise: <100 or 75% of anginal HR), painful episode journal and NTG use, caution asthmatics
41
bisoprolol brand
zebeta
42
bisprolol doses
initial: 1.25mg qd target: 10mg qd
43
metropolol succinate brand
troprol xl
44
metoprolol succinate doses
initial: 12.5mg- 25mg qd target: 200mg qd
45
nebivolol brand
bystolic
46
nebivolol doses
5-40mg qd
47
non-selective beta blocker
propranolol
48
propranolol brand
hemangeol, inderal
49
propranolol dose
80-160mg qd
50
tPA mimic
alteplase, reteplase, tenecteplaase
51
tPA mimics AEs
bleeding
52
tPA mimics monitoring
Bleeding, angioedema, hx of stroke, peptic ulcer, severe HTN, or trauma
53
alteplase brand
activase
54
altplase doses
15mg bolus, 0.75mg/kg over 30 min, 0.5mg/kg over 60 min
55
reteplase brand
retevase
56
reteplase dose
10u bolus, 10u boluse after 30 min
57
tenecteplase brand
TNKase
58
tenecteplase doses
30mg if <60kg, 35mg if 60-70kg, 40mg if 70-80kg, 45mg if 80-90, 50mg if >90kg
59
LMWH
enoxaparin
60
enoxaparin brand
lovenox
61
enoxaparin dose
prophylaxis -30mg sc q12h or 40mg sc qd treatment- 1mg/kg q12h or 1.5mg/kg qd 0.5mg/kg iv bolus
62
enoxaparin AEs
bleeding, injection site rash, fever
63
enoxaparin monitoring
CBC with platelet, SCr, fecal occult blood, anti Xa levels
64
Factor Xa inhibitor
fondaparinux
65
fondaparinux brand
arixtra
66
fondaparinux dose
2.5mg sc qdaily
67
fondaparinux AEs
bleeding
68
fondaparinux Monitoring
anti Xa levels, scr
69
direct thrombin inhibitor
bivalirudin
70
bivalirudin brand
angiomax
71
bivalirudin dose
0.7mg/kg, then 1.75mg/kg/hr
72
bivalirudin AEs
hypotension, nausea, bleeding, muscle ache, HA
73
bivalirudin monitoring
activated clotting time, signs of bleeding
74
thiazides
hydrochlorothiazide
75
hydrochlorothiazide brand
microzide, esidrix, hydrodiuril
76
hydrochlorothiazide dose
initial: 25mg/day max: 50mg/day
77
hydrochlorothiazide AEs
Hypokalemia, hypomagnesemia, hypercalcemia, hyperuricemia, hyperglycemia, hyperlipidemia, sexual dysfunction, Li toxicity
78
hydrochlorothiazide monitoring
CI with sulfa allergy or anuria, K+, Mg2+, Ca2+, uric acid, blood glucose, lipids
79
Class V antiarrhythmic
digoxin
80
digoxin brand
lanoxin, digitalis, digox
81
digoxin dose
0.125mg-0.25mg daily
82
digoxin AEs
nausea, vomiting, dizziness, HA, thrombocytopenia
83
digoxin monitoring
Serum digoxin, K+, Ca2+, Mg2+, SCr, signs of digoxin toxicity
84
ARN/ARB
sacubitril/valstartan
85
sacubitril/valsartan brand
entresto
86
sacubitril/valsartan AEs
Hypotension, hyperkalemia, dizziness, angioedema
87
sacubitril/valsartan monitoring
scr, K+, angioedema
88
anticoagulant
heparin
89
heparin brand
hemochron, hep-lock
90
heparin dose
80u/kg iv bolus, then 18u/kg/hr infusion
91
heparin AEs
bleeding, thrombocytopenia, osteoporosis, hypersensitivity
92
heparin monitoring
aPTT, signs of bleeding
93
late iNa blocker
ranolazide
94
ranolazide brand
ranexa
95
ranolazide dose
500-1000mg bid
96
ranolazide AEs
constipation, nasuea, dizziness, ha, dose-related increase in QT-interval
97
ranolazide monitoring
Don't use with strong 3A4 inhibitors or inducers or drugs that also prolong QT interval, watch renal function
98
alpha 1 antagonist + nonselective beta blockers
labetalol, carvedilol
99
alpha 1 anatagonist + non selective beta blockers AEs
Orthostatic hypotension, tingling of skin, nausea, dizziness, fatigue, see B-blockers
100
alpha 1 antagonist + non selective beta blockers monitoring
bp, hr
101
labetalol brand
normodyne, trandate
102
labetalol dose
200-400mg bid
103
carvedilol brand
coreg
104
carvedilol dose
initial: 3.125mg bid or 10mg qd target: 25mg bid or 80mg qd
105
Decrease TG
omega-3 fatty acid
106
omega-3 fatty acid brand
lovaza
107
omega-3 fatty acid dose
4g qd
108
omega-3 fatty acid AEs
burping, indigestion, bad taste in mouth, smelly breath
109
omega-3 fatty acid monitoring
TG, LDL-C, liver function tests
110
HCN inhibitor
ivabradine
111
ivabradine brand
corlanor, procoralan
112
ivabradine dose
2.5-5mg bid, adjust q2w based on hr max- 7.5bid
113
ivabradine AEs
afib, bradyarrhythmia
114
vassopressor
dobutamine, dopamine
114
ivabradine monitoring
HR, bradyarrhythmia
115
dobutamine brand
dobutrex
116
dobutamine AEs
angina, tachyarrhythmia, HA, dyspena
117
Dobutamine monitoring
ECG, HR, BO, pulmonary wedge pressure, CO, K+
118
dopamine brand
inotropin, dopastat
119
dopamine dose
2-50mcg/kg/min
120
dopamine AEs
chest pain, HTN, palpitations, tachycardia, HA, Anxiety, dyspnea
121
dopamine monitoring
ECG, BP, HR, SCr, CVP, caution extravasation
122
COX-1 inhibitor
aspirin
123
aspirin dose
75-162mg qd
124
aspirin AEs
gi bleeding, intercrannial bleeds, hypersensitivity, major bleeding
125
aspirin monitoring
bleeding, gi ulcers
126
furosemide dosing HF
initial- 20-40mg QD or BID usual- 20-60mg QD or BID
127
torsemide dosing HF
initial- 10-20mg QD usual- 10-80mg QD
128
spironolactone dosing HF
crcl> 50 - initial: 12.5 - 25mg QD -maintenance: 25mg QD crcl<50 -initial: 12.5 QD or every other day -maintenance: 12.5-25 mg QD
129
eplerenone dosing HF
crcl>50 - initial: 25mg QD -target: 50mg QD crcl< 50 -initial: 25mg every other day -maintenance: 25mg QD
130
sacubitril/valsartan dosing HF
high dose- 49/51mg BID; max - 97/103 mg BID low dose- 24/26mg BID
131
hydrochlorothiazide brands HF
esidrix, hydrodiuril
132
hydrochlorothiazide dosing HF
initial- 25mg QD max- 100m QD
133
enalapril dosing HF
initial- 2.5-5mg target- 10mg bid
134
captopril dosing HF
initial- 6.25-12.5mg TID target- 50mg TID
135
lisinopril dosing HF
initial- 2.5-5mg QD target- 20-40mg QD
136
quinapril dosing HF
initial- 5-10mg BID target- 20-40md BID
137
ramipril dosing HF
initial- 1.25-2.5mg QD target- 5mg BID or 10mg QD
138
fosinopril dosing HF
initial- 5-10mg QD target- 40mg QD
139
losartan dosing HF
initial- 25-50mg target- 150mg
140
valsartan dosing HF
initial- 20-40mg BID target- 160mg BID
141
candesartan dosing HF
initial- 4mg QD target- 32mg QD
142
bisoprolol dosing HF
initial- 1.25mg QD target - 10mg QD
143
carvedilol dosing HF
initial- 3.125mg BID target- 25-50mg BID CR - initial: 10mg QD -target: 80mg QD
144
metoprolol tartrate dosing HF
initial-12.5-25mg QD target- 200mg QD
145
SGLT2 inhibitors HF
dapagliflozin and empagliflozin 10mg QD
146
hydralazine dosing HF
initial- 25mg TID/QD target-75mg TID max- 100mg TID
147
isdn dosing HF
initial- 20mg TID/QD target- 40mg TID max- 80mg TID
148
ivabradine dosing HF
2.5mg BID, adjust q2 weeks based on HR
149
digoxin dosing HF
0.125-0.25mg QD

Theraputics (4 decks)

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