Cardio Pharmacology Flashcards by Zane freeman

Q

Hydrochlorothiazide

A

thiazide diuretic: blocks early distal tubular Na uptake

risk of hypokalemia

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Q

Furosemide

A

Loop diuretic: blocks loop of Henle Na uptake
risk of hypokalemia
Most effective class

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Q

Spironolactone

A

Aldosterone antagonist - Potassium-sparing Diuretic:

blocks aldosterone stimulated Na uptake in late distal and cortical collecting tubules; hyperkalemia risk

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Q

Eplerenone

A

Aldosterone antagonist - Potassium-sparing Diuretic:

blocks aldosterone stimulated Na uptake in late distal and cortical collecting tubules; hyperkalemia risk

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Q

Amiloride

A

Sodium-channel inhibitor Potassium sparing
Blocks Na uptake in late distal and cortical collecting tubules
Hyperkalemia risk

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Q

Tramterene

A

Sodium-channel inhibitor Potassium sparing
Blocks Na uptake in late distal and cortical collecting tubules
Hyperkalemia risk

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Q

Nifedipine

A

Calcium channel blocker dihydropyridine

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Q

Nicardipine

A

Calcium channel blocker dihydropyridine

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Q

amlodipine

A

Calcium channel blocker dihydropyridine

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Q

Diltiazem

A

Calcium channel blocker

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Q

Verapamil

A

Calcium channel blocker -most heart selective

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Q

Minoxidil

A

Potassium channel opener

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Q

Prozasin

A

Alpha blocker -reduces sympathetic mediated tone

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Q

terazosin

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Doxazosin

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Phentolamine

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Phenoxybenzamine

A

Alpha blocker -reduces sympathetic mediated tone

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Q

Bosentan

A

Blocks ET vasoconstrictor receptors

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Q

Nitrodilators

A

vasodilation via cGMP

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Q

Captopril

A

ACEI

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Q

enalapirl

A

ACEI

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Q

Lisinopril

A

ACEI

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Q

Losartan

A

angiotensin receptor blocker

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Q

valsartan

A

angiotensin receptor blocker

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candesartan

angiotensin receptor blocker

Aliskiren

Renin inhibitor

Hydralazine

Direct-acting vasodilator

Metoprolol

Beta blocker

Propranolol

beta blocker

Clonidine

alpha2 adrenoceptor agonist

guanabenz

alpha2 adrenoceptor agonist

guanfacine

alpha2 adrenoceptor agonist

alpha-methyldopa

alpha2 adrenoceptor agonist

Hexamethonium

ganglion blocker

Trimethaphan

ganglion blocker

Camsylate

ganglion blocker

Antiarrhythmic Class I

Sodium Channel Blockers

Antiarrhythmic Class II

Beta blockers

Antiarrhythmic Class III

Potassium Blockers

Antiarrhythmic Class IV

Ca-Channel Blockers

Quinidine, procainamide, disopyramide

Antiarrhythmic Class IA

Lidocaine, Tocainide, mexiletine

Antiarrhythmic Class IB

Flecainide, Propafenone, Moricizine

Antiarrhythmic Class IC

Propanolol, metoprolol, acebutolol, esmolol

Antiarrhythmic Class II Beta blockers

Amiodarone

Antiarrhythmic Class III | use: supra vent & vent tachy

Dronedarone

Antiarrhythmic Class III | Atrial fib and flutter

Bretylium

Antiarrhythmic Class III | Life threatening v tach / fib

Sotalol

Antiarrhythmic Class III, II | V tach; A fib/flutter

Ibutilide

Antiarrhythmic Class III | A fib/flutter

Dofetilide

Antiarrhythmic Class III | A fib/flutter

Verapmil, diltiazem

Antiarrhythmic Class IV Ca channel blockers

Adenosine

Slows SA nodal firing Dec AV nodal conduction Uses: rapidly suppress supravent tacky caused by AV nodal reentry

Atropine

Blocks excessive vagal tone Inc Av Nodal conduction & velocity Uses: Acute AV block reversal

Digoxin

Activates Vagus | Uses: A flutter/fib to dec vent rate

Magnesium Salts

Enhance opening of Katp channels -> hyperpolarizatoin | Uses: AMI associated arrythmias

Tx for Sinus Tachy

II, IV

Tx for A fib/flutter

IA, IC, II, III, IV, Digitalis, Adenosine

Tx for AV bloks

Atropine

Tx for V tach

I, II, III

Tx for Premature V complexes

II, IV, Mg salts