Cardio Sketchy Flashcards
(14 cards)
dihydropyridines
act on vascular smooth muscle
non-dihydropyridines
act on heart
- ipine suffix
dihydropyridine calcium channel blockers
CCB act by…
block voltage-dependent calcium channels of cardiac and smooth muscle
uses for dihydropyridine CCB
hypertension, angina (including Prinzmetal), Raynaud phenomenon
uses for non-dihydropyridine CCB
hypertension, angina, afib
nimodipine
dihydropyridine CCB, used for subarachnoid hemorrhage (prevents vasospasm)
nicardipine
dihydropyridine CCB used for hypertensive emergency
clevidipine
dihydropyridine CCB used for hypertensive emergency
adverse effects of dihydropyridine CCB
peripheral edema, flushing dizziness, gingival hyperplasia
adverse effects of non-dihydropyridine CCB
cardiac depression, AV block, constipation, hyperprolacinemia
hydralazine mechanism
more cGMP leads to smooth muscle relaxation - dilates arterioles more than veins, decreasing afterload
hydralazine use
severe hypertension, HF, usually given with beta blocker to prevent reflex tachycardia
black patients respond best to ……… for hypertension
CCB and HTCZ