Cardiology Flashcards
(46 cards)
Indications for Lipid lowering therapy
1) Primary prophylaxis if CVD High Risk i.e. a 15% chance of CV event in 5 years
2) Secondary prophylaxis post ACS or stroke
Causes of heart failure
Causes of secondary hypertension
- Primary Aldosteronism (low K) High Aldos low Renin
- Renovascular hypertension (High Renin and Aldos)
- Liddles syndrome
- Licorice
- Cushings
- OSA
ECG of LVH
- V1 S wave >35mm
- V5/6 R wave >35mm
- LAD
- LV Strain: ST depression / TWI V5-6
Blood pressure treatment target
< 140
<120 if mod - High cardiovascular risk
Conservative BP Management
- Weight loss (1kg reduced systolic by 2mm/Hg) –> Aim BMI <25 and Waist <94cm M or <80cm women
- CPAP
- Exercise
- Alcohol reduction
- Salt reduction (between 3-5grams)
Management strategy for uncontrolled Hypertension
- poor adherence 1
- hyperaldosteronism(investigateandaddspironolactone)orotherrareprimarycause
(e.g. Cushing’s syndrome, coarctation) and recommend: - attempted weight loss
- salt and alcohol restriction
- exercise
- sleep apnoea treatment (if indicated).
Evaluation for Heart Transplant
Immunosuppresion in Heart Transplant
Ciclosporin or Tacrolimus
Diltiazem often used as cyclosporin agent to reduce dose required.
*SE = Hyperlipidaemia and Hypertension
Routine tests post heart transplant
- Weekly biopsy 1 weeks then fortnightly for 1 month then 6 monthly routinely
- Twice annual CAG -> at risk of premature CAD (allograft arteriopathy) and as denervated heart it is typically painful
Survival post Cardiac Transplant
1 year –> 90%
5 year –> 75%
10 year –> 50%
Treatment of Cardiac Allograft Rejection
Endomyocardial biopsy
3 days Methylprednisolone
Rebiopsy
- Other Rx: ATG, Muronumab
Aetiology of Atrial Fibrillation
- Advancing age
- OSA
- Alcohol use
- WPW
- Hypertension
- Mitral valve disease (MR or MS)
- HCM
- IHD
- Recent thoracic or abdominal surgery
- ASD
- PE
- Thyrotoxicosis
Dominant A wave
Pulmonary hypertension
Tricuspid stenosis
Pulmonary stenosis
Canon A Wave
AV Block
Ventricular Tachycardia
Dominant V Wave
Tricuspid regurgitation
Elevated Central venous pressure
-Right heart failure
-Tricuspid stenosis / regurgitation
-Pericardial effusion / constrictive pericarditis
-SVC obstruction
-Fluid overload
-hyperdynamic circulation (fever, anaemia, thyrotoxicosis)
Apex beat
-Sustained -> pressure loaded i.e AS / HTN
-Hyperkinetic / volume overloaded in MR / AR
-Double impulse in HCM
Left Parasternal impulse
Right ventricular hypertrophy or Left atrial enlargement
1st heart sound
Loud: Mitral stenosis, Tricuspid stenosis.
Soft: mitral regurgitation, left bundle branch block, 1st degree heart block
Second Heart sound
Aortic:
-Loud: hypertension, mechanical valve.
-Soft: Aortic Stenosis, Aortic regurgitation.
Pulmonary:
- Loud: pulmonary HTN,
- Soft: Pulmonary Stenosis
Fixed Split S2:
* heard throughout entire cardiac cycle best at P2
- Pulmonary stenosis
- Pulmonary hypertension
- ASD
- RBBB
Reversed Splitting (P2 first)
*Split heard only during expiration
- LBBB
- Aortic stenosis
Third Heart sound
Rapid filling of compliant ventricle.
*differs from split S2 as it is low pitched (should disappear with diaphragm and be present with bell) Also best heart at a apex as opposed to P2
May be normal under 40YOA
aetiology:
- AR
- MR
- LVF
Fourth heart sound
*Always pathological
Filling of poorly compliant ventricle
Aetiology:
- Aortic stenosis
- Hypertension
- Ischaemic heart disease
- HCM
Differential diagnosis of murmur