Cardiology Flashcards
(51 cards)
Class Ia Anti-arrhythmics
Quinidine, Procainamide
Na-channel blocker
prolong action potential
Class Ib Anti-arrhythmics
Lidocaine, Tocainide
Na-channel blocker
shorten action potential
Class Ic Anti-arrhythmics
Flecainide, Propafenone
Na-channel blockers
no change in action potential
Class II Anti-arrhythmics
beta-blockers
Class III Anti-arrhythmics
Amiodarone, Sotalol, Bretylium
K-channel blockers
Class IV Anti-arrhythmics
Verapamil, Diltiazem
Ca-channel blockers
Posterior MI
V1-V2
PDA
Septal MI
V1-V3
(septal branch of) LAD
Anterior MI
V2-V4
LAD
Inferior MI
II/III/aVF
(acute marginal branch of) RCA
Lateral MI
I/aVL
Circumflex
Ductus Arteriosus
connection between pulmonary trunk and descending aorta so oxygenated blood from placenta can bypass lungs and enter systemic circulation
Foramen Ovale
Connection between RA and LA so oxygenated blood from placenta can bypass lungs and enter left heart/systemic circulation
Ductus Venosus
Connection between umbilical vein (carrying oxygenated blood from placenta) and IVC
Closure of DA
decreased PG-e
Closure of FO
decreased IVC/RA pressure after cord-clamping
Closure of DV
increased SVR
Familial Hypercholesterolemia
defect in LDL receptor
autosomal dominant
homozygous > severe than heterozygous (LDL >600 vs >250)
Familial Combined Hyperlipidemia
increased ApoB production
high LDL and TG
Familial Defective AboB-100
defect in LDL particle
Physical exam findings in inherited hypercholesterolemia
Xanthomas- tendons/skin especially behind knees and ankles
Xanthelasmas- eyelids
Retinal Cholesterol Emboli
LDL Target Levels
Healthy: <100
CAD Risk Factors for LDL Goals
Smoking
HTN
HDL 45,
Age (male >45, female >55)
***HDL >60 protective
HMG-CoA Reductase Inhibitors
Statins
Greatly decrease LDL
decrease TG, increase HDL
SE: myositis, increase LFT’s