Cardiology Flashcards

(44 cards)

1
Q

What is the dose of aspirin and ticagrelor given during an M.I?

A

Aspirin 300mg
Ticagrelor 180mg
STAT

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2
Q

What are the cautions for ticagrelor?

A

Asthma
COPD
Bradycardia

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3
Q

What are some cardiac and non cardiac causes of elevated BNPs?

A

Cardiac:

  • Heart failure
  • ACS
  • Myocarditis

Non- cardiac:

  • advance age
  • ischemic stroke
  • SAH
  • COPD
  • Burns
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4
Q

In an echocardiogram for heart failure, what are you looking for?

A

LV systolic function - ejection fracture

LV dimision

Valvular abnormalities

Diastolic function

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5
Q

What are the levels of ejection fracture?

A

Normal >55%
Mild 45-55%
Moderate 36-44%
Severe <35%

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6
Q

What signs may be seen on ultrasound of a P.E?

A

RV dilation
RV hypokinesis
Pulmonary hypertension

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7
Q

What murmur may be heard with aortic dissection?

A

Aortic regurgitation
- due to widen of the aortic outlet causing back flow.

intussusception may occur

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8
Q

What are the indications for CABG?

A

> 50% stenosis of the main left artery “critical main left stem disease”

2-3 Artery involvement “triple disease”

Poor ventricular function associated with multi-vessel disease

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9
Q

When a patient is put on cardiopulmonary bypass - what must they be given and then what follows this?

A

Heparin to avoid clots within the machine.

this is revered with protamine once the blood returns to the patient.

*blood is drained via the great veins, either IVC or SVC and returned directly into the aorta

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10
Q

What drug is given to stop the heart during a cardiopulmonary bypass?

A

Cardioplegia
- high K+ load.

doesn’t cause ischemia

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11
Q

What is the procedure of choice for aortic stenosis, and what is the alternative for those who are not fit for surgery?

A

Aortic valve replacement is treatment of choice.

TAVI is the option for those who are unfit for surgery.

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12
Q

Contrast the differences between mechanical and tissue AVRs

A

mAVR:

  • lifelong
  • Durable
  • requires anticoagulation
  • clicks
  • haemolysis

tAVR:

  • 10-15years
  • non-durable
  • doesn’t require anticoagulation
  • non-audible
  • vegetations grow
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13
Q

What are the indications for a mitral valve replacement?

A

Severe MR

Severe symptoms

Papillary muscle rupture - usually post M.I

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14
Q

When would you only control the rate in someone with AF?

A

Structurally abnormal heart

> 65 years old

Persistent AF

Hypertension

Previously failed treatment

Less symptomatic

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15
Q

What type of aortic dissection will have a weak/ absent radial pulse? and what is the management?

A

Stanford type B
- it is distal to subclavian

  • Medical management
  • to control BP
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16
Q

What are the indications for surgery in aortic dissection?

A

Type A

Persistent pain

Failure of medical management

Aortic rupture

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17
Q

What conditions are associatted with VSD?

A

Down’s syndrome

Edwards syndrome

Patau’s syndrome

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18
Q

What is the most common congenital heart disease, and what syndrome is it highly associated with?

A

Bicuspid Aortic valve

Turner’s syndrome

19
Q

What heart murmur would you expect to hear with coarctation of the aorta?

A

Systolic murmur in between the shoulder blades, usually nearer the left

Harsh systolic ejection over the left side

20
Q

What are some of the systemic outcomes of Eisenmenger’s syndrome?

A

Increased erythrocytes
- increased blood viscosity and clots

Damaged endothelium due to high pressure
- increased bleeding and poor platelet activation

Gout

Acne

21
Q

What are some of the systemic signs of Eisenmenger’s syndrome?

A

Dyspnea

Syncope

Cyanosis

Finger clubbing

Right ventricular heave

22
Q

List some conditions where pregnancy is contraindicated:

A

Primary pulmonary hypertension
- carries a mortality of 30-50%

Marfan’s syndrome with dilated aortic root

Severe aortic stenosis

Severe mitral stenosis

Severe LVSD

23
Q

What congenital heart disease is associated with berry aneurysms?

A

coarctation of the aorta

24
Q

What vessels maybe used in bypass graft?

A

venous
- great saphenous vein

Arterial
-left internal mammary artery

25
If a patient continually suffers from collapse, outwith the direct disease/ condition, what other factors should one consider?
Hydration status Excessive diuresis Medications - polypharmacy Age
26
Why does Aortic stenosis cause chest pain?
Two fold: - Left ventricular hypertrophy, demands more blood but does not receive it as well - Reduced blood following into the coronary sinuses due to hypokinetic valves blocking entrance
27
What are the characteristics of pericarditis pain?
Pain located retrosternally Pain not associated with exertion Sharp/ shooting pain. Not constrictive Radiates to left shoulder Relieved by sitting forward
28
Outline the management of cardioversion of AF:
<48 hours - herparinse - Electro- Cardioversion - Pharmacological (amiodarone if structural heart disease) >48 hours - 4 week anti-coagulation or - confirm with transesophageal US
29
What investigation can be done to establish if there is a thrombus present prior to cardioverting in a patient with AF?
Transoepahgeal US
30
Outline the management of heart failure:
1. ACE + Beta blocker 2. Mineral receptor blocker 3. - this is specialist input - Ivabrindine (<35% EF and >75bpm sinus) - Dixogin (AF present) - Sacubitril/ valsartan (<35%) 4. - LVAD - CRD * flu vaccine yearly * one off pneumococcal vaccine
31
What signs may you see regarding the liver in heart failure?
Enlarged smooth liver which is pulsatile
32
How can the pulmonary arterial pressure be measured, how can the pulmonary venous and left atrium pressures be measured?
Cardiac catheterisation passed into a vein and through right side of heart and into the pulmonary vessels. - direct measuring can then occur To measure the Pulmonary venous pressure or left atrium the catheter whilst in the pulmonary circulation can wedge off the arterial flow - thus only measuring the venous and atrial pressures * pulmonary capillary wedge pressure
33
What type of cardiac catherization is used to assess left ventricular function including aortic regurgitation?
Arterial catherization Accessed via the: - Right femoral or - Radial
34
What are some of the indications for cardiac catherization?
Diagnosis and assessment of coronary arterial disease + Therapeutic intervention (angioplasty, Stenting) Valvular disease - diagnosis and assessment + Therapeutic intervention Congenital heart disease - diagnosis and assessment + Therapeutic intervention Electrophysiology for diagnosis and therapeutic intervention Measuring pressures
35
Outline some of the pre-procedural management for cardiac catheterisation and list some complications:
Bloods: - FBC - U&Es - Coagulation studies - LFTs CXR ECG IV access (on the left) Complications: - Haemorrhage from enter site - Angina - Arrhythmias - Vessel spasm (causing loss of distal pulses) - Aortic dissection - Infection at sight
36
What is the most common type of primary cardiac tumour?
Atrial Myxoma
37
What are the symptoms of obstructive cardiomyopathy?
*obstruction due to spetal hypertrophy. most common cause of sudden death in young person. - AD pattern - sporadic mutation Symptoms: - syncope/ presyncope on effort - dyspnoea - Chest pain - asymptomatic Signs: - Double apical pulsation - Jerky carotid pulse (rapid ejection followed by obstruction) - ejection systolic murmur
38
What ECG findings might you see with obstructive cardiomyopathy?
Left ventricular hypertrophy Twave inversion Non-specific ST changes
39
What investigations and treatments are there for obstructive cardiomyopathy?
Investigations: - ECG - Echo - MRI of heart Management: - Beta blocker +/- calcium channel blockers - ICD *ACE inhibitors are contraindicated due to reduced expansion of pre-load = reduced cardiac output
40
What are the causes of dilated cardiomyopathy?
``` Familial Alcohol Myocarditis Thyroidtoxicosis Neuromuscular - Duchene ```
41
What are the signs and symptoms of dilated cardiomyopathy?
Symptoms: - Heart failure symptoms - AF - VTEs Signs: - dynamic Apex beat - High HR - Low BP - Hepatosplenomegaly - Raised JVP
42
How is dialted cardiomyopathy investigated and treated?
Investigations: - Bloods - BNP and U&Es - ECG (Non-specific findings) - Echocardiogram - Heart MRI Management: - Heart failure management - VTE prophylaxis - Heart transplant (if indicated)
43
What are the causes of mitral stenosis and when is it considered severe?
Rheumatic fever - most common valve Congenital Lutembacher's syndrome - ASD + mitral stenosis Severe is when the annulus is <1cm in diameter Symptoms appear after <2cm
44
What are some of the signs of mitral stenosis and what does the murmur sound like?
Face: - Malar flush Pulse: - AF Jugular: - distended - right sided heart failure Palpation - palpable first heart sound Right ventricular heave - when the right side is affected. Murmur: Mid diastolic murmur with opening snap- rumble sound - apex *heard best with patient in the left lying position Loud S1 sound