Cardiology Part 2 Flashcards

(45 cards)

1
Q

Which of the following is NOT true in reference to Dilated cardiomyopathy?

A. Dilated Cardiomyopathy is 95% of all cardiomyopathies. B. It is most common in men
C. Onset is between 20-60 years of age
D. It is diastolic dysfunction that leads to ventricular dilation.

A

D. It is SYSTOLIC dysfunction that leads to ventricular dilation: weak, dilated heart

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2
Q

What are the causes for Dilated cardiomyopathy?

A
  1. Idiopathic* MC
  2. Viral myocarditis
  3. Toxic: ETOH, cocaine, anthracyclines (Doxorubicin), radiation tx
  4. Other: pregnancy, hyper/hypothyroidism
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3
Q

A patient is having systolic heart failure symptoms with an audible S3. You suspect dilated cardiomyopathy. What cardiac murmur(s) might you hear on auscultation?

A

Mitral OR Tricuspid regurgitation

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4
Q

A patient is having systolic heart failure symptoms with an audible S3. You also hear mitral regurgitation. The patient also has a laterally displaced PMI. How would you confirm your diagnosis of this patient?

A

Echo:

  1. Left ventricular dilation
  2. Decreased Ejection fraction
  3. Regional or Global left ventricular hypokinesis

Dilated Cardiomyopathy

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5
Q

A patient is having systolic heart failure symptoms with an audible S3. You also hear mitral regurgitation. The patient also has a laterally displaced PMI. What would a CXR of this patient look like?

A

Cardiomegaly
Pulmonary edema
Pleural effusion

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6
Q

A patient is having systolic heart failure symptoms with an audible S3. You also hear mitral regurgitation. The patient also has a laterally displaced PMI. Echo reveals Left ventricular dilation, decreased ejection fraction, and regional left ventricular hypokinesis consistent with Dilated Cardiomyopathy. What is the best management for this patient?

A

Standard heart failure treatment:

  1. ACE I
  2. Diuretics
  3. BB (if no decompensated CHF)
  4. Digoxin
  5. Na restriction
  6. Implantable Defibrillator if EF < 30-35%*
  7. Cardiac transplant*
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7
Q

Apical left ventricular ballooning is an indication of what condition?

A

“Broken heart syndrome” = Takotsubo Cardiomyopathy

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8
Q

A patient with Restrictive cardiomyopathy is more likely to have which of the following?

A. Kussmaul’s sign
B. S3
C. S4
D. Decreased ejection fraction

A

A. Kussmaul’s sign (JVP increases with inspiration)

-Patient may or may not have S3

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9
Q

What is the most common etiology of Restrictive cardiomyopathy?

A

Infiltrative disease: Amyloidosis*

-Sarcoidosis

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10
Q

How would an Echo of a Restrictive cardiomyopathy patient look like?

A
  1. Ventricles non-dilated with normal wall thickness
  2. Marked dilation of both atria*
  3. Diastolic dysfunction(systolic seen if advanced)
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11
Q

A patient is highly suspected of Restrictive Cardiomyopathy. How would you expect their EKG to look like?

A

Low voltage

+/- arrhythmias

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12
Q

“Bright speckled myocardium” seen on an Echo is an indication of what condition?

A

Restrictive cardiomyopathy

*seen in amyloidosis

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13
Q

How is a patient with Restrictive cardiomyopathy managed?

A

No specific tx: Symptomatic tx; GENTLE diuresis; vasodilators

Treat underlying disorder:

  • Chelation for hemochromatosis
  • Steroids for sarcoidosis
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14
Q

What is Hypertrophic Cardiomyopathy?

A

Inherited GENETIC disorder of inappropriate LV and/or RV hypertrophy (especially septal)

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15
Q

What is the pathophysiology of Hypertrophic cardiomyopathy?

A

Subaortic Outflow obstruction narrowed LV outflow tract 2ry to:

  1. Hypertrophied septum
  2. Systolic anterior motion (SAM) of the mitral valve & papillary muscle displacement
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16
Q

What is the most common initial complaint in Hypertrophic cardiomyopathy?

A

Dyspnea

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17
Q

When a patient with Hypertrophic Cardiomyopathy experiences sudden cardiac death, what is this due to?

A

Ventricular fibrillation

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18
Q

A patient is complaining of dyspnea and chest pain. EKG revealed LVH and CXR revealed cardiomegaly. What would you expect the murmur to sound like on auscultation?

A

Harsh systolic crescendo-decrescendo murmur best heard at the LLSB

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19
Q

While auscultating, you hear a systolic crescendo-decrescendo murmur at the LLSB of a patient complaining of dyspnea. What would make this murmur louder?

A

Decreased venous return

Valsalva and standing

  • may have loud S4*
  • mitral regurgitation
  • S3
  • Pulsus bisferiens
20
Q

A patient is complaining of dyspnea and chest pain. EKG revealed LVH and CXR revealed cardiomegaly. A harsh systolic crescendo-decrescendo murmur is heard at the LLSB. How do you manage this patient?

A

Counseling to avoid dehydration & extreme exertion/exercise!!!!

ICD placement

Medical: BB 1st line*

Surgical: Myomectomy

Alcohol septal ablation

21
Q

What is Constrictive pericarditis?

A

thickened, fibrotic, calcified pericardium that restricts ventricular diastolic filling

22
Q

What is the most common symptom of Constrictive pericarditis?

23
Q

What will you hear on auscultation on a patient with Constrictive pericarditis?

A

Pericardial knock*: high pitched 3rd heart sound

-Due to sudden cessation of ventricular filling in early diastole from thickened inelastic pericardium

24
Q

How is constrictive pericarditis diagnosed?

A

Echo: pericardial thickening*

25
With a patient with constrictive pericarditis, what will the CXR look like?
Pericardial calcification
26
What does a "square root" sign mean on Cardiac catheterization?
Constrictive pericarditis
27
What is the management for constrictive catheterization?
Pericardiectomy -diuretics may be used for sxs control
28
A patient is diagnosed with Hyperlipidemia. He wants to know what causes this. How do you respond?
1. Hypercholesterolemia: hypothyroidism, pregnancy, kidney failure 2. Hypertriglyceridemia: DM, ETOH, obesity, steroids, estrogen
29
Which of the following can be a clinical manifestation of Hyperlipidemia? A. Cholecystitis B. Hepatitis C. Pancreatitis D. DM
C. Pancreatitis NOT DM--DM can cause hyperlipidemia
30
A patient is seen in the clinic. She is not complaining about anything and has come for her annual physical. She is not taking any medications; she says she is "fit as a fiddle." On PE, you notice Xanthomas and xanthelasma. What is your suspicion of this patients diagnosis?
HYPERLIPIDEMIA xanthelasma = lipid plaques on the eye lids
31
When does screening for hyperlipidemia for high-risk patients begin?
Initiate screening at age 20-25 for males | 30-35 for females
32
What defines a high-risk patient for hyperlipidemia?
> 1 risk factor: HTN; smoking; family hx OR 1 severe risk factor
33
When does screening for lower risk patients with hyperlipidemia begin?
Initiate screening at age 35 for males; 45 for females
34
For which type of patients is hyperlipidemia recommended?
1. Patients with type 1 or 2 DM between ages 40-75 2. Patients without cardiovascular disease ages 40-75 & > or = 7.5% risk for having a heart attack or stroke within 10 years 3. People > or = 21 y/o with LDLs > or = 190 mg/dL 4. Any patient with any form of clinical atherosclerotic cardiovascular disease
35
Which medications best lower elevated LDL?
Statins* | Bile acid sequestrants
36
Which medications best lower elevated triglycerides?
Fibrates* | Niacin
37
Which medications best increase HDL?
Niacin* | Fibrates
38
What medications are beneficial for a type II DM patient with hyperlipidemia?
Fibrates, statins
39
Which hyperlipideamia drug can cause hyperglycemia and thus, you should use caution when prescribing to a DM patient?
Niacin
40
What are the goal levels for hyperlipidemia?
LDL < 100 Total cholesterol < 200 HDL > 60
41
Nutritionally, what can you recommend to patients to eat for hypertriglyceridemia?
``` Omega 3 fatty acids Salmon Flaxseed Canola oil Soybean oil Nuts ```
42
What is the MOA of statins?
HMGcoA reductase inhibitors Inhibits the rate-limiting step in hepatic cholesterol synthesis Increases LDL receptors (removes LDL from the blood) Reduces triglycerides Shown do decrease cardiovascular complications
43
What is the only hyperlipidemia medication safe in pregnancy?
Bile acid sequestrants
44
Which medication inhibits intestinal cholesterol absorption?
Ezitimibe * may be used with statins
45
What are some side effects of Bile Acid sequestrants you need to be aware of?
GI effects: nausea, vomiting, bloating, crampy abdominal pain, increased LFTs* Raises triglyceride levels--so best used with someone with high LDL and normal triglycerides