Cardiomyopathy and channelopathies Flashcards
1
Q
Hypertrophic cardiomyopathy is caused by gene mutations in which proteins?
A
Sarcomeric (contractile)
2
Q
HCM may cause…
A
Angina, dyspnoea, palpitations, dizzy spells or syncope
3
Q
What would be seen on an ECG of someone with HCM?
A
Ventricular arrhythmia
4
Q
What type of symptoms does dilated cardiomyopathy (DCM) usually present with?
A
Heart failure symptoms
Breathlessness, fatigue, fluid retention
5
Q
What is channelopathy caused by?
A
Ion channel protein gene mutations (potassium, sodium or calcium)
6
Q
Channelopathies include…
A
Long QT, short QT, Brugada and CPVT
7
Q
Name some aortovascular syndromes
A
Marfan, Loeys-Dietz, vascular Ehler Danlos (EDS)
8
Q
What kind of life-saving treatments are available?
A
ICD, beta-blockers, statins, vascular surgery
Lifestyle modifications
