Cardiopulmonary Events PTT CA2 Flashcards
(42 cards)
What is a normal CVP?
0 - 8 mmHg
What is a normal PCWP (Pulmonary Capillary Wedge Pressure)?
5 - 12 mmHg
What is a normal Cardiac Output?
4 - 6 L/min
What is a normal Cardiac Index?
2.5 - 4.2 L / min / m2
What is a normal SVR?
770 - 1500 dynes / sec / cm5
What is a normal PVR?
40 - 140 dynes / sec / cm5
List the Parameters of Hypovolemia
CVP
HR
PAP
ART
CO
SVR
List the Parameters of Hypovolemia
CVP - Low
HR - High
PAP - Low
ART - Low
CO - Low
SVR - High
List the Parameters of Sepsis
CVP
HR
PAP
ART
CO
SVR
PVR
List the Parameters of Sepsis
CVP - Low
HR - High
PAP - Low
ART - Low
CO - High
SVR - Low
PVR - Low
List the Parameters of CHF
CVP
HR
PAP
ART
CO
SVR
List the Parameters of CHF
CVP - High
HR - (Dependent on situation)
PAP - High
ART - Low
CO - Really low
SVR - High
List the Parameters of Peripheral Hypertension
CVP
HR
ART
SVR
List the Parameters of Peripheral Hypertension
CVP - Low
HR - Low
ART - (High)
SVR - High
List the Parameters of Pulmonary Hypertension
CVP
PAP
ART
PVR
List the Parameters of Pulmonary Hypertension
CVP - High
PAP - High
ART - Low
PVR - High
What are the hemodynamic parameters of Tamponade for:
CVP
HR
PAP
ART
CO
What are the hemodynamic parameters of Tamponade for:
CVP - High
HR - High
PAP - High
ART - Low
CO - Low
What is the treatment for Septic Shock?
-
Norepinephrine (A1, A2 and B1 agonism)
- Helps combat your low SVR and has some ionotropy - Vasopressin
- Phenylephrine (Helps with SVR but does drop your CO)
What is the treatment for acute CHF?
- Dobutamine (B1 agonist)
- Dopamine
<3 mcg/kg/min DA1 agonist
5 - 10 mcg/kg/min B1 and B2
10 - 20 mcg/kg/min Alpha agonism
- Epinephrine
<3 mcg/min - Beta 1 and Beta 2
> 3 mcg/min - Alpha receptors are recruited
What is the treatment for Peripheral Hypertension?
1. Nitroprusside
Reduction in (Afterload > Preload)
50 - 100 mcg (0.5 - 3 mcg/kg/min)
2. Nitroglycerine
Reduction in (Afterload < Preload)
50 - 100 mcg (0.5 - 3 mcg/kg/min)
3. Nicardipine (CCB)
5 - 15 mg/hr
1-4 mcg/kg/min
What is the mechanism of action of nicardipine?
By deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum, nicardipine inhibits the influx of extracellular calcium across the myocardial and vascular smooth muscle cell membranes.
The decrease in intracellular calcium inhibits the contractile processes of the myocardial smooth muscle cells, causing dilation of the coronary and systemic arteries, increased oxygen delivery to the myocardial tissue, decreased total peripheral resistance, decreased systemic blood pressure, and decreased afterload.
What is the treatment for pulmonary hypertension?
-
Dobutamine with Nitroglycerine
- Dobutamine Dose 3 - 20 mcg/kg/min or 0.2 - 1.4 mg/min -
Milrinone
- 0.2 - 0.75 mcg/kg/min - Nitric Oxide
- Prostaglandin E1
What is the treatment for tamponade?
- IVF (Possibly)
- Iontropes (Possibly)
- Avoid High Airway Pressures
What are the components of myocardial oxygen supply?
1. Coronary Anatomy
Obstruction (CAD) vs. Spasm (Variant angina) vs. Extraluminal Compression (Anomalous Coronaries)
2. HR
Diastolic Time
3. Perfusion Pressure of the Coronaries
Left CPP = DBP - LVEDP
Right CPP = DBP - RVEDP
4. Arterial Oxygen Content
amount of oxygen bound to hemoglobin (1.34 * Hb * SaO2) plus the oxygen dissolved in plasma (0.0031 * PaO2)
Hypoxemia
Anemia
What are the components of myocardial oxygen demand?
- Tachycardia
- Wall tension
- Contractility
What are the components of Wall Tension?
This relationship is similar to the Law of LaPlace, which states that:
Wall tension (T) is proportionate to the pressure (P) times radius (r) for thin-walled spheres or cylinders. Therefore, wall stress is wall tension divided by wall thickness.
The exact equation depends on the cardiac chamber shape, which changes during the cardiac cycle; therefore, a single geometric relationship is sometimes assumed. For this reason, the above relationship is expressed as a proportionality to highlight how pressure, radius and wall thickness contribute to afterload.

Pulmonary capillary wedge pressure (PCWP) is used as a surrogate of what?
Pulmonary capillary wedge pressure (PCWP) is used as a surrogate of LVEDP
What is the arterial oxygen content equation and normal value?
(Hgb * 1.31 * SaO2) + (0.003 * PaO2)
CaO2
20 ml O2/dL blood
What is the mixed venous oxygen content equation and normal value?
(Hgb * 1.31 * SvO2 ) + (0.003 * PvO2)
CvO2
15 ml O2/dL blood

