Cardiovascular Flashcards
A 57-year-old female has come to the pharmacy regarding her new medication that has been prescribed by her specialist. She has been prescribed amiodarone for ventricular tachycardia. She has been made aware that the medication causes phototoxicity and as such, can cause painful skin problems if the skin is exposed to the sun whilst on amiodarone. She has asked for your advice regarding an appropriate sunscreen protection when she is away on her holiday in the summer. Which of the following sunscreen agents and active ingredients will not prevent phototoxicity caused by amiodarone?
A) Padimate O and oxybenzone
B) Padimate O and avobenzone
C) Zinc Oxide
D) Titanium Dioxide
E) Octyl Methoxycinnamate and homosalate
D – 0.4% glyceryl trinitrate therefore 400mg (0.4g x 1000) to convert into milligrams in 100g. in
120g = 120/100 x 400 = 480 milligrams
A 45-year-female has recently been diagnosed with ovarian cancer. The oncologist has referred the patient for surgery to remove the tumour. You are observing the patient’s chart as hospital pharmacist on the general surgery ward. You are aware all patients require VTE prophylaxis assessment conduct prior to admission and post admission for those with limited mobility after an elective surgery. You note that this patient falls within the highest VTE risk category and requires VTE prophylaxis (tinzaparin) on discharge for certain number of days treatment. How many days’ worth of VTE prophylaxis (tinzaparin) treatment should the patient be discharged with after surgery?
A) 7 days
B) 14 days C) 21 days D) 28 days
E) 30 days
D – See chapter 2 under venous thromboembolism. Pharmacological prophylaxis in general surgery should usually continue for at least 7 days post-surgery, or until sufficient mobility has been re-established. Pharmacological prophylaxis should be extended to 28 days after major cancer surgery in the abdomen, and to 30 days in spinal surgery.
Mr AK has come to your heart failure clinic for a medication review. He has been stable on the maximum dose of ACE inhibitor and beta-blocker for 8 weeks. However, you notice Mr AK’s ankles are still swollen indicating his heart failure symptoms have not been adequately controlled. You decide to refer Mr AK to his specialist for a review of his symptoms, where a few days later a letter from the heart failure consultant has recommended you initiate the next phase of heart failure treatment. The consultant has mentioned that Mr AK’s ejection fraction is <35% and he is at class III of the New York Heart Association classification for heart failure. Which of the following medications would be the most appropriate to initiate MR AK’s as step regimen for managing his heart failure symptoms?
A) Ivabradine
B) Hydralazine
C) Digoxin
D) Sacubitril/Valsartan
E) Isosorbide mononitrate
D) Sacubitril/Valsartan
