Cardiovascular anatomy Flashcards
(26 cards)
Components of blood
Plasma, red blood cells, white blood cells, platelets
Erythrocytes (RBC)
Transport O2 and CO2 carried on hemoglobin molecules. Biconcave discs. No nuclei or organelles. Production in bone marrow. Finite lifespan, destroyed in spleen.
Leucocytes (WBC)
Nucleated cells. Include lymphocytes, neutrophils, monocytes, eosinophils and basophils. Differentiated by appearance and function. Produced in bone marrow. Use blood vessels for transport - actions are in tissues. Involved in immune response.
How are Leucocytes involved in immune response?
Lymphocytes involved in adaptive immunity (also monocytes/macrophages). Others in innate response to infection, tissue damage, allergies. Increased production and release in response to disease.
Lymphocyte
antibodies (B/plasma cells), cell killing (T), regulation (T), some involved in less specific cell killing (NK)
Monocyte
become macrophages in tissues - engulf and destroy foreign material, dead cells, abnormal cells, pathogens, regulation of immune response.
Neutrophil
fight bacterial infection, tissue damage
Eosinophil
migrate to areas of allergic reactions and kill parasites
Basophil
allergic response - releasing histamine and other substances
Platelets
Fragments of the cytoplasm of large cells (megakaryocytes) located in bone marrow (mammals). Involved in clotting, repair of small areas of damage to blood vessel walls.
Heart structure
Large muscular organ in ventral thoracic cavity, between the lungs. Cone shaped.
Four main chambers of heart
2 Atria, 2 ventricles, described as left and right
Pericardium
Serous membrane sac (2 layers) that stops heart moving excessively and reduces friction. Outer layer with thick fibrous covering = parietal layer. Thin inner layer (attached to heart wall) = visceral layer.
Myocardium
heart wall, striated muscle type unique to heart (cardiac muscle), involuntary
Endocardium
heart internally covered by thin, smooth layer
Heart valves
cusps of atrioventricular valves are anchored to ventricle walls by fine cords (chordae tendineae) and muscular projections (papillary muscles)
Pulmonary circulation
supplies and drains blood from lungs and involved in gas exchange. pumped from right side of heart to lungs.
systematic circulation
transports blood to and from rest of body. pumped from left side of heart.
Arteries
Thick, relatively rigid walls - maintain cross-sectional shape when bisected. Move blood away from heart. Blood under high pressure. In protected locations
Veins
thinner walls, collapsed (usually), generally greater diameter than associated arteries. Move blood towards heart. Blood under low pressure. May be located more superficially. Valves in small and medium veins.
Blood vessel
lined by endothelium. Wall arranged in concentric layers - Tunica interna, tunica media, tunica externa
Tunica interna
lined with endothelium
tunica media
circulatory arranged smooth muscles, elastic fibers, variable thickness - poorly developed in veins, more connective tissues
Tunica externa
connective tissue surrounding vessel