Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

revision year 1 > Cardiovascular drugs > Flashcards

Cardiovascular drugs Flashcards

(85 cards)

Start Studying
1
Q

name all the types of antihypertensive drugs

A 
ACEis
ARBs
Diuretics
BB
CBB
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

MOA ACEis

A

blockers production of ACE which converts angiontensin I - angiotensin II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

U for ACEi

A

HT and HF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Egs ACEi

A

pril

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

SE ACEi

A

dry cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

when are ACEis contraindicated?

A

pregnancy and renal issues

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

ARB MOA

A

binds to angiotensin II receptors instead of angiotensin II receptors preventing rise in BP as no RENIN

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Uses of ARB

A

HT, HF

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Egs ARBs

A

sartan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Contraindications of ARB

A

renal and pregnancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

MOA beta blockers

A

binds instead of adrenaline to B receptors decreasing HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

what g protein does Bblockers bind to?

A

Gs protein

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Uses BBLOCKERS

A

HT, HF, UA, Arrhythmias

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

egs B blockers

A

olol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

name the beta recptor found in the heart

A

b1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

name b1 selective bblockers

A

Atenolol and metoprolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

SE BB

A

heart block
bronchospasm asthma
hypoglycaemia esp diabetes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

contraindications for BB?

A

asthma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

d:chronotropic

A

affects rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

d:inotropic

A

affects contractility

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

when are alpha 1 antagonists used?

A

resistant HT

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

names alpha 1 anatgonist

A

‘sins’

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

MOA CCBs

A

block Ca2+ going into cells reducing contractiility decreasing CO and hence MAP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

MAP equation with CO

A

MAP = CO X TVR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Use CCBs
HT | Angina
26
name dihydropyridine CCB
dipine
27
name benzothiazepine CCB
zem
28
name phenylakylamines CCB
pamil
29
SE CCB
ankle oedema
30
what must verapamil be avoided in
HF
31
name the 3 toyes of diurectics?
loop, k sparing and thiazide
32
where do diurectics act
nephron in the kidneys
33
strongest diurectic
Loop
34
MOA diurectics
stop NA+ being absorbed into blood and therefore water, so bp is reduced as less fluid rention in in blood
35
U diurectices
HF and HT thiazide
36
lopp diurectic example
fruseomide
37
thiazide diurectic example
benzopuremithiazide
38
K sparing thiazide
spirolactone
39
SE of loop diurectic and thazide
hypokalaemia, hyponeutraemia, increased gout
40
SE k sparing
hyperkalaemia, metabolic acidosis
41
name the classification by which the antiarrhythmic drugs are classified
vaughan williams
42
what calss are Na+ channel drugs found in?
class I.
43
what class are B blockers found in?
class II
44
what class are K channel blockers found in?
class III
45
ca2+ channel blockers are found in which class ?
class IV
46
MOA adnensosine?
acivates K channels and deactivates l type Ca2+ channels, decreasing cintraction velocity
47
uses of adenosine?
WPW syndrome, ATrial tachy (paraoxysmal)
48
when must adenosine NOT be used?
AF and atrial flutter
49
what does digoxin do?
increase force of contraction
50
uses of digoxin?
AF, A Flutter and HF severe
51
SE of digoxin
heart block VF, VT
52
what are CLass I A+B used for
ventricular arrhythmias
53
does class IA have a slow/fast refractory period?
slow
54
what type of tissue does class IB work on?
ischaemic
55
name class IA drug?
amide
56
name class IB drug?
lidocaine
57
What does class IC treat?
AF
58
name a drug thats in class IC?
flucanide
59
name 2 drugs in class III
amidarone and dronedarone
60
pulmonary alveolitis (honeycombing) is a SE of what drugs?
CLASS III
61
uses of class III
atrial and ventricular
62
name a cox inhibitor antiplatlet?
aspirin
63
name a ADP antagonist antiplatelet?
clopidegrel
64
what type of drug is tricagrelor?
antiplatelet
65
MOA of antiplatelets?
activate plasminogen-pkasmin dissolving thrombi
66
Uses antiplatelets?
MI and UA
67
name a drug in fibrinolytics?
strptokinase
68
what is the rate limiting step in cholesterol synthesis?
HMG reductase
69
describe the mechnism of statins?
cholestorol is synthesised in liver via cinversion of glucose-acetyl coA - LDL via HMG reductase, these block this means compensatory mechanism is unblanced so extra LDL receptors released by liver to clear LDL
70
what do you give is statin contraindicated?
fibrate
71
MOA nitrates?
nitrates converted to NO, vasodilator, causes SM relaxation, easier for heart to beat
72
name 2 nitrates?
GTN and isosorbide mononitrate
73
which type of drug bypasses 1st pass metabolism?
nitrates
74
anem the anticoagulant clases
vit k antagonists glycoaminoglycans syntheticpentasaccaride inhibitors DOACs
75
MOA vit k anatgonists
modifies clotting factors V,VII,IX,X
76
eg k anatagonists
warfarin
77
what must you monitor with warfarin and what should you keep it at?
2-3 INR
78
what route must LMWH be given by?
SC
79
MOA of LMWH/heparin?
inhibits factor Xa
80
MOA fondaparinux?
inhibits factor Xa
81
what class of drug does rivaoxaban belong to and what is its MOA?
inhibits factor Xa- DOACs
82
what drug has a slate grey rash as a side effect?
amidarone
83
what drug has a yellowed vision headache as a side effect?
digoxin
84
what drug is a competative antagonist of muscarinic receptors and blocks parasympathetic responses which reverses bradycardia following an MI?
atropine
85
SE of spironolactone?
gynaecomastia and hyperkalaemia

revision year 1 (7 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions