Cardiovascular Pharmacology Flashcards Preview

Cardiology USMLE Step 3 > Cardiovascular Pharmacology > Flashcards

Flashcards in Cardiovascular Pharmacology Deck (8)
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1

List three vasodilators

  1. Nitroglycerine
  2. Isosorbide dinitrate
  3. Nitroprusside

2

List the characteristics of nitroglycerine

3

List the characteristics of isosorbide dinitrate

4

List the characteristics of nitroprusside

5

Mecahnism of actions of nitrates

Nitrates work by causing dilation of both arteries and vein which leads to decreased preload and afterload resulting in reduced myocardial O2 demand, but effect on veins and preload is far greater than on arteries and afterload

6

Characteristics of digoxin toxicity

  • Nausea
  • Vomiting
  • Anorexia
  • Fatigue
  • Confusion
  • Visual disturbance
  • Cardiac abnormalities

7

Medications that can cause digoxin toxicity

  • Verapamil
  • Quinidine
  • Amodiarone
  • Spirinolactone

8

How does verapamil cause digoxin toxicity?

Verapamil inhibits the renal tubular secretion of digoxin resulting in almost 70 to 100% increase in serum digoxin levels