Cardiovascular System Flashcards

1
Q

What is the purpose of the cardiovascular system?

A

Supply oxygen and nutrients to the tissues and organs and to remove waste products

To defend the supply of nutrients to organs by;
Maintaining cardiac output
Maintaining organ perfusion pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

How does the CV system supply oxygen and nutrients and remove waste products?

A

Is a closed circuit system
Heart muscle is central dual chamber pump

Perfusion is maintained through adequate pressure in the system. Mean arterial pressure (MAP)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is the pressure in the four chambers?

A
Right Heart (low pressure)
Right atrium, right ventricle 
Left heart (high pressure) 
Left atrium, left ventricle
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Name the four valves?

A

Tricuspid, pulmonary

Mitral, aortic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are coronary arteries?

A

Heart muscle is supplied with oxygen and nutrients by

  • left coronary artery
  • right coronary artery

Left coronary artery supplies left ventricle

These arteries are narrow and highly susceptible to obstruction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is cardiac output?

A

Volume of blood pumped per ventricle per unit of time

CO = heart rate x stroke volume

CO= 72 bpm x 70ml = 5040ml
Approx 5 litres

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Describe control of stroke volume?

A

Sympathetic neurones release norepinephrine and circulating epinephrine
Increases contractility
Stronger and shorter systole

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Describe control of heart rate?

A

Sympathetic neurones release norepinephrine and circulating epinephrine increases heart rate

Parasympathetic neurones (vagus) releases ACh, slows heart rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is total peripheral resistance (TPR) ?

A

Functions of vessels

Local control of resistance (vessel tension)

Central control of resistance (vessel tension)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

How to calculate MAP?

A

MAP = CO x TPR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Local control of blood flow?

A

Metabolic autoregulation and tissue hypoxia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Central control of blood flow (maintains MAP)?

A

Sympathetic nervous system releases noradrenaline

Adrenal gland releases adrenaline

Picked up by alpha receptors (cause vasoconstriction) and B2 receptors (vasodilation)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

State the electrical conducting pathways?

A
Sinoatrial node 
Atrioventricular node 
Bundle of HIS 
Bundle branches 
Purkinje fibres
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

To work the heart needs?

A

Electrical normality- nodes and pathways able to initial electrical activity and pass on effectively

Structural/ mechanical normality- valves, vessels and myocardium

Sufficient oxygen supply- lack of oxygen can damage both electrical pathway and myocardium itself and ability to respond / pass on electrical activity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is an ECG?

A

Records and analyses electrical activity throughout cardiac cycle

Electrical activity radiates through surrounding tissue and is picked up by electrodes on skin

Converts currents into waveforms that represent depolarisation/ repolarisation to identify rhythm and conduction disturbances

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the functions of blood?

A
  1. Transportation
    Dissolved gases, nutrients, hormones and metabolic wastes, excess body water for excretion
  2. Buffer
    regulation of pH and ions in interstitial fluid
  3. Protection
    Restriction of fluid loss at injury sites
    Defence against toxins and pathogens
    Stabilising body temperature
17
Q

What is the composition of blood?

A

Plasma:
Water
Substances- nutrients + O2/CO2
Proteins- buffer , clotting, antibodies

Formed elements:
Erythrocytes
Leukocytes
Thrombocytes

18
Q

What are the types of plasma proteins?

A

Albumins

Globulins

Fibrinogen

Active and inactive enzymes and hormones

19
Q

What are erythrocytes?

A

Red blood cells

Oxygen transport in blood

20
Q

What are leukocytes?

A

White blood cells

Body’s defence mechanisms

21
Q

What are thrombocytes?

A

Platelets

Membrane bound cell fragments involved in clotting

22
Q

What is haemoglobin?

A

Globin- 4 polypeptide chains

Binds to oxygen to form oxyhaemoglobin

Each heme is associated with one polypeptide chain and contains an Fe 2+ ion that combines reversible with oxygen molecule

23
Q

What is heamostasis?

A

Response sequence stopping bleeding

  1. Vascular spasm- artery/arteriolar smooth muscle contraction
  2. Platelet plug formation
    Platelet adhesion
    Platelet release reaction
  3. Blood clotting (coagulation)