Cartilage Flashcards Preview

Histology Exam 2 > Cartilage > Flashcards

Flashcards in Cartilage Deck (27):
1


Cartilage is a type of _____ tissue and has a _____ appearance.


Cartilage is a type of connective tissue and has a non-descript appearance (very pale).

2

Define Cartilage


Specialized connective tissue with high tensile strength which consists of cells embedded in an amorphous, gel-like substance.

3


_____ are cells associated with cartilage.


Chondrocytes

4


What is the term for the small space/compartment that chondrocytes reside in?


Lacunae

5


What is the term for a lacunae that consists of 2-6 chondrocytes?


Cell nests

6


Even though vessels are often visible passing through cartilage it is _____

Avascular

7


Cartilage has considerable tensile strength due to the presence of what?


Collagen fibers provide strength to cartilage

8


What are the two types of glycosaminoglycans present in the matrix of cartilage?


1. Hyaluronic Acid

2. Chondroitin Sulfate

*Structurally these components resemble a bottle brush with a long unbranched hyaluronic acid and several protein core molecules attached that have chondroitin sulfate  groups radiating out and electrostatically binding to the collagen fibrils.

9


The presence of sulfate groups on the proteoglycan the matrix stains _____


The sulfate groups impart an acid nature to the matrix and thus adult cartilage stains basophilically.

10

What is the specialized capsule-like sheath of dense irregular connective tissue that surrounds the cartilage?


Perichondrium

11

True or False:

The perichondrium is absent in fibrocartilage


True

12


What are 4 functions of cartilage?


1. Allows for friction-free movement of bones

2. forms supporting part of nose, larynx, trachea, bronchi and external ear

3. Protects articular surfaces of bones

4. Serves as a template for development of bones of the extremities, vertebral column and pelvis

13


What specialized structure in long bones is cartilage associated with?


Growth plate

14

What is a chondroblast?


Young chondrocyte that synthesizes and secretes amorphous ground substance and collagen (active chondrocyte).

15

What is the term for the matrix surrounding each lacunae?


territorial matrix

16

What is interstitial growth?


Growth from within-cartilage expands by adding matrix internally from existing chondrocytes

17


What is appositional growth?


growth from the outside; matrix is added externally to the developing cartilage.  The cells of the perichondrium divide and secrete ground substance and fibers.

18


What are 3 types of cartilage?


Hyaline, Elastic, and Fibrocartilage

19

For hyaline cartilage discuss where it might be located, type of fibers and the presence or absence of perichondrium.

Hyaline Cartilage

Location-Articular surfaces of bones, nose, larynx, trachea, embryonic skeleton

Fiber type-Collagen

Perichondrium-Present except the articular surface of bone which does not have perichondrium

20


True or False: The perichondrium is present in all hyaline cartilage?


False-The perichondrium is absent from the articular surface of bone

21


Discuss Elastic cartilage location, fiber type, and presence or absence of perichondrium.


Elastic Cartilage

Location-Pinna of the ear, epiglottis, auditory tube

Fibers-Elastic with some collagen

Perichondrium-present

22


For fibrocartilage discuss the location, fiber type and presence or absence of perichondrium.


Fibrocartilage

Location-Intervertebral disks, menisci of stifle joint

Fibers-Collagen bundles

Perichondrium-absent

23


How is cartlage repair different in older versus younger animals?


Cartilage is repaired by both appositional and interstitial growth in young animals but in adults is usually replaced by fibrous connective tissue

24

True or False: Cartilage repair is a slow process


True

25

True or False: the Veterinary field was using nutritional supplements to aid in the repair and maintenance of cartilage long before MD's started suggesting it to their patients.


True

26


_____ is a common disease in small, long dogs and usually presents as a neurologic problem.


Intervertebral disc disease

27


Damage to the _____ is common during tears of the cranial cruciate ligament in large breed dogs.


Menisci