Catalysis--enzymes & cofactors

Question 1

Which enzyme(s) use Cu2+ as a cofactor?

Answer 1

cytochrome oxidase

Question 2

Which enzyme(s) use Fe2/3+?

Answer 2

Cytochrome oxidase, catalase, peroxidase

Question 3

Which enzyme(s) use K+?

Answer 3

pyruvate kinase

Question 4

Which enzyme(s) use Mn2+?

Answer 4

arginase, ribonucleotide reductase

Question 5

Which enzyme(s) use Mg2+?

Answer 5

hexokinase, glucose-6-phosphatase, pyruvate kinase

Question 6

Which enzyme(s) use Mo?

Answer 6

dinitrogenase

Question 7

Which enzyme(s) use Ni2+?

Answer 7

urease

Question 8

Which enzyme(s) use Se?

Answer 8

glutathione peroxidase

Question 9

Which enzyme(s) use Zn2+?

Answer 9

carbonic anhydrase, alcohol DH, carboxypeptidases A and B

Question 10

coenzyme biocytin, chem groups it transfers, and it’s dietary precursor

Answer 10

CO2, biotin

Question 11

coenzyme CoA, chem groups it transfers, and it’s dietary precursor

Answer 11

acyl groups, pantothenic acid and other compounds

Question 12

coenzyme coenzyme B12, chem groups it transfers, and it’s dietary precursor

Answer 12

h atoms and alkyl groups, vit b12

Question 13

coenzyme FAD, chem groups it transfers, and it’s dietary precursor

Answer 13

electrons; riboflavin (vit b2)

Question 14

coenzyme lipoate, chem groups it transfers, and it’s dietary precursor

Answer 14

electrons and acyl groups, not required in diet

Question 15

coenzyme NAD, chem groups it transfers, and it’s dietary precursor

Answer 15

hydride ion, nicotinic acid (niacin)

Question 16

coenzyme pyridoxal phosphate, chem groups it transfers, and it’s dietary precursor

Answer 16

amino groups, pyridoxine (vit b6);

Question 17

coenzyme tetrahydrofolate, chem groups it transfers, and it’s dietary precursor

Answer 17

one-carbon groups, folate

Question 18

coenzyme thiamine pyrophosphate, chem groups it transfers, and it’s dietary precursor

Answer 18

aldehydes; thiamine, vit b1

Question 19

class number 1 enzymes & types of rxns catalyzed

Answer 19

oxidoreductase; transfer electrons (hydride ions or H atoms)

Question 20

class number 2 enzymes & types of rxns catalyzed

Answer 20

transferases; group transfer rxns

Question 21

class number 3 enzymes & types of rxns catalyzed

Answer 21

hydrolases; hydrolysis rxns–>transfer of functional groups to water

Question 22

class number 4 enzymes & types of rxns catalyzed

Answer 22

lyases; addition of groups to double bonds or formation of double bonds by removal or groups

Question 23

class number 5 enzymes & types of rxns catalyzed

Answer 23

isomerases; transfer of groups within molecules to yield isomeric forms

Question 24

class number 6 enzymes & types of rxns catalyzed

Answer 24

ligases; formation of C-C, C-S, C-O, C-N bonds by condensation reactions coupled to cleavage of ATP or similar cofactor