Causes of infectious disease Flashcards

1
Q

What is an infectious disease?

A

A condition that adversely affects the normal functioning of an organism or parts of an organism

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2
Q

Difference between infectious and non infectious disease?

A
  • Infectious diseases are caused by pathogens and can be transmitted from one organism to another
  • non infectious that are not caused by pathogens and are not contagious
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3
Q

What are pathogens?

A

Any organism that is capable of causing disease in its host

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4
Q

What are the types of pathogens?

A

Bacteria, viruses, fungi, protozoans, prions

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5
Q

What is virulence?

A

the degree of pathogenicity or the degree of which a pathogen can cause disease in its host

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6
Q

What is the difference between sign vs symptom?

A
  • Sign= objectively measurable factors such as increased body temperature, rash, hypertension
  • symptom: factors reported by a patient such as pain, fatique, nausea
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7
Q

What is pathogenicity?

A

The ability of a pathogen to cause disease in a host.

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8
Q

What is bacteria

A

Unicellular, prokaryotic organisms which do not contain membrane bound organelles

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9
Q

How do bacteria cause disease?

A

producing toxins or chemicals that harm the host’s bodies or by direclting invading host tissues and causing damage

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10
Q

How is bacterial diseases treated?

A

Chemical treatment with antibiotics, surgical removal of dead issue, wound cleansing

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11
Q

What is fungi

A
  • Eukaryotic organisms with a cell wall comprised of chitlin
  • can be unicellular or multicellar
  • not capable of producing own nutrients- heterotrophic
  • most fungi live on dead plant and animal material- role as decomposer
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12
Q

What is an example of a unicellular fungi and a multicellular fungi

A

yeasts- unicellular
moulds- multicellular

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13
Q

What is protozoa

A
  • unicellular eukaryotic organisms
  • no cell wall
  • binary fission
  • Live in the human gastrointestinal tract and pools and sewages
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14
Q

Common diseases caused by protozoa

A
  • malaria
  • amoebic dysentery
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15
Q

Macroorganisms (macroparasites)

A
  • multicellular eukaryotic organisms
  • visible to naked eye
  • classifed into two groups; endoparasites and ectoparasites
  • some cause disease directly
  • others act as vectors
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16
Q

List from the smallest to largest pathogens

A

Prions, viruses, bacteria, protozoa, fungi macroparasites

17
Q

List some examples of diseases caused by bacteria

A
  • Tuberculosis
  • Pneumonia
  • tetanus
  • dysentery
18
Q

Common diseases caused by fungi

A
  • Thrush
  • Ringworm
19
Q

Examples of macroparasites

A

Endoparasites: tapeworms
Ectoparasites: ticks, fleas,mites

20
Q

What is a virus

A
  • A microscopic pathogen that consist of RNA or DNA that is enclosed by a protective protein coat
21
Q

What is a capsid

A

The protective protein coat that surrounds the genetic material of a virus.

22
Q

Antivirals

A

Medications or substances used for the treatment of viral infections by inhibiting the replication of viruses

23
Q

Retroviruses

A

Viruses that contain RNA as their genetic material

24
Q

What are the living Characteristics of Viruses

A

Viruses possess genetic material (DNA or RNA) that allows them to pass on genetic information

25
Q

Non-living Characteristics of Viruses

A

iruses are not composed of cells and can be crystallized. They rely on a host cell for reproduction and metabolism.

26
Q

Size of Viruses

A

Viruses are smaller than 500 nm in size, making them visible only under an electron microscope.

27
Q

What is the infectious part of a virus?

A

the genetic material (DNA or RNA) enclosed within the capsid.
It carries the genetic info for the virus to replicate and infect host cells.

28
Q

What are the steps for virus replication?

A
  1. The virus attaches to the surface of a host cell.
  2. The virus enters the host cell and releases its genetic material. (nucleic acids)
  3. The viral genetic material takes control of the host cell’s machinery and begins to replicate viral genetic materia
  4. New viruses are synthesised from proteins
  5. The host cell is destroyed or ruptured to release the newly formed virisues
  6. Newly released virions infect other host cells and process repeats
29
Q

What are diseases caused by viruses

A
  • measles
  • influenza
  • AIDs (HIV)
  • herpes
  • chicken pox
30
Q

What are pathogenic prions

A
  • smallest type of pathogen
  • Abnormal type of protein that can cause disease in mammals
  • contains no genetic material
31
Q

Which body systems are mostly affected by pathogenic prions?

A

The nervous system, including the brain, nerves, and spinal cord.

32
Q

How do pathogenic prions cause disease?

A

When an abnormal prion comes into contact with a normal prion, it can trigger it to fold abnormally and clump in the brain

33
Q

What happens to brain tissue affected by pathogenic prions?

A

Brain tissue becomes filled with holes, giving it a sponge-like appearance.

34
Q

How are diseases caused by pathogenic prions referred to?

A

They are called transmissible spongiform encephalopathies.

35
Q

Where are normal prions found in organisms?

A

Brain and spinal cord

36
Q

Examples of diseases caused by prions

A
  • mad cow disease
  • CJD
37
Q

What are some ways in which pathogenic prions can be transmitted?

A
  • Ingesting tissue containing prions,
  • using contaminated surgical equipment
  • inheriting a mutated gene for infected prions
  • receiving contaminated growth hormone injections
  • infected corneal implants from donors.