CBC Flashcards

(53 cards)

0
Q

Leukopenia

A

Low WBC count

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1
Q

Leukocytosis

A

High WBC count

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2
Q

Polycythemia/Erythrocytosis

A

High red count

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3
Q

Anemia

A

Low red count

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4
Q

What does hemoglobin carry and where to/from?

A

Carries oxygen to the tissues and carbon dioxide to the lungs

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5
Q

What two things determine normal range of hemoglobin?

A

Age and sex

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6
Q

Who has the highest hemoglobin levels? Lowest?

A

Highest: neonates; lowest: children.

Men > women; older > younger

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7
Q

What does hematocrit measure?

A

Total volume to RBCs relative to the total volume of whole blood in a sample

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8
Q

What are hemoglobin, hematocrit, and RBC count used to determine?

A

MCH, MCV, MCHC

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9
Q

Terms for high and low MCV

A

Macrocytic; microcytic

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10
Q

Mean cell hemoglobin

A

Average weight of hemoglobin in RBCs

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11
Q

Mean cell hemoglobin concentration

A

Average concentration of hemoglobin in RBCs

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12
Q

What can cause a high MCHC

A

Lab error or spherocytes

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13
Q

In what disease are spherocytes present?

A

Hemolytic anemia, hereditary spherocytosis

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14
Q

Low MCHC

A

Hypochromic

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15
Q

High platelet count

A

Thrombocytosis

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16
Q

Thrombopenia

A

Low platelet count

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17
Q

What is red cell distribution width?

A

Numerical expression that correlates with the degree of anisocytosis (variation in size of the population of red cells)

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18
Q

What can RBW monitor?

A

Therapy for iron deficiency anemia or megaloblastic anemia

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19
Q

When does a RDW increase and decrease?

A

Increases when new, normal sized RBCs are produced; decreases as normal cell population becomes the majority

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20
Q

Mean platelet volume

A

Numerical expression of platelet size

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21
Q

Primary function of neutrophils

22
Q

High number of neutrophils

23
Q

Neutropenia

A

Low number of neutrophils

24
Two types of neutrophils
Bands and segs
25
Eosinophils- function
Pro-inflammatory cells capable of protecting or damaging the host depending on the situation
26
Eosinophils- neutralize, phagocytic, toxic to???
Neutralize basophil products; mildly phagocytic; granules are toxic to parasites
27
Basophil- primary function
Enhance immuno-inflammatory reaction
28
High basophil count
Basophilia
29
Basopenia
Low basophil count
30
What two low cell counts are usually a problem?
Basopenia and monocytopenia
31
Lymphocyte function depends on what?
Type of lymphocyte
32
T cells vs B cells
T cells- cellular immunity; B cells- humoral immunity
33
High lymphocyte count
Lymphocytosis
34
Lymphocytopenia
Low lymphocyte count
35
Reactive/Atypical lymphs
Lymphocytes look difference when responding to various stimuli; usually during viral infections like mono
36
Monocytes- major function
Phagocytosis
37
High monocyte count
Monocytosis
38
Monocytopenia
Low monocyte count
39
Spherocytes are found in
Hemolytic anemia and hereditary spherocytosis
40
Target cells are found in...
IDA, sickle cell anemia, thalassemia
41
Schistocytes are found in...
Microangiopathic hemolytic anemias
42
Howell-Jolly bodies are found in...
Post-splenectomy
43
Reticulocyte count measures
Percentage of reticulocytes
44
Why can reticulocytes be stained?
They contain RNA, mature RBCs don't
45
What does the reticulocyte count show?
How quickly they are being produced and released by bone marrow
46
What would cause an increased rate of RBC production?
Bleeding or hemolytic anemia
47
Lower percentage of reticulocytes
Caused by a nutritional deficiency
48
What does erythrocyte sedimentation rate determine?
Presence of inflammation
49
Do RBCs fall faster or slower during an illness?
Faster
50
What does the bone marrow exam evaluate?
Various hematopoietic disorders like leukemia, lymphomas, anemias
51
What additional thing can bone marrow exams determine?
If leukemia is in remission
52
What tests can monitor disease therapy?
ESR, bone marrow exam