CBSSA 1

Question 1

Prostate cancer tumor grading

Answer 1

NOT T-N-M… Gleason Scale (Architecture, appearance, cell arrangement)

Question 2

Oxidative Burst

Answer 2

NADPH Oxidase

Question 3

Imatinib

Answer 3

Bcr-Abl RTK inhibitor (CML)

Question 4

Primary Compensatory mechanism for decreased blood volume s/p hemorrhage

Answer 4

Capillary fluid reabsorption

Question 5

Granuloma formation

Answer 5

Th1 -> IFNy -> Macrophage -> TNFa -> maintenance

Question 6

Area of action of Sildenafil

Answer 6

Corpus Cavernosa

Question 7

Vibrio Cholera initial tx

Answer 7

Fluids (D50) -> therefore reabsorption of Na and glucose from lumen into blood

Question 8

Penis innervation: 1) Parasymp 2) Symp 3) Somatic

Answer 8

1) Pelvic 2) Hypogastric 3) Pudendal

Question 9

Kidney function that uses the most O2

Answer 9

Tubular Reabsorption, NOT acid-base homeostasis

Question 10

Changes in circulation with excercise?

Answer 10

1) Increased total cross-sectional pulmonary microcirculation (distention and incr. microvasculature)
2) decr. total peripheral resistance
3) incr. stroke volume

Question 11

Lesions that can be on sun-exposed and non sun-exposed skin?

Answer 11

Dysplastic Nevi

Question 12

Complications of Cystic Fibrosis (Chr. 7 gene deletion –> ATP gated Cl- channel)

Answer 12

Pancreatitis (steatorrhea, vitamin deficiency), liver damage, meconium ileus, biliary cirrhosis

Question 13

Pharyngeal Pouches

Answer 13

1) Middle Ear, Eustachian Tube, Mastoid
2) Tonsils (Agammaglobulinemia = absent)
3) Thymus, Inferior PT (DiGeorge)
4) Thyroid, Superior PT (DiGeorge)

Question 14

Absent enzyme in SCID

Answer 14

Adenosine Deaminase –> incr. adenosine –> toxic

Question 15

Syphilis stages

Answer 15

1) Painless chancre
2) Rash, Condyloma Lata,
3) Gummas (non-caseating granuloma), Tabes Dorsalis
Congenital) sniffles, sores on mouth angle