CC Flashcards

(53 cards)

1
Q

True of cholesterol metabolism, except

A. free cholesterol is the inactive form of
cholesterol with cytotoxic property
B. Free cholesterol and phospholipids
have a hydrophilic property
C. both have hydrophilic and
hydrophobic properties
D. the process of esterification is a
“detoxification” step cholesterol ester
is almost 90% in plasma

A

B. Free cholesterol and phospholipids
have a hydrophilic property

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2
Q

It is the recommended fasting hour in
most clinical biochemistry tests: 6-8 hours

A

8-12 hours

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3
Q

True of R4s, except:

A. it is caused by random errors
B. it is observed after 2 consecutive
days
C. R means random error
D. difference between the highest and
lowest control result exceeds 4s

A

B. it is observed after 2 consecutive
days

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4
Q

It is the ideal reference limit:

A

2s

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5
Q

It is the most abundant lipid in human
plasma:

A

Cholesterol

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6
Q

True of creatinine, except:

A. a measure of the completeness of
24-hour urine collection
B. plasma creatinine may not be
increased until renal function has
deteriorated more than 50% plasma
creatinine is usually within the
reference limit in muscular diseases
C. in muscular dystrophy, plasma
creatine is decreased while urinary
creatinine is elevated

A

C. in muscular dystrophy, plasma
creatine is decreased while urinary
creatinine is elevated

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7
Q

Control values are computed based on: 1.mean
2. median
3. standard deviation
4.variance

A

1 and 3

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8
Q

if urea is the most abundant NPN in
plasma, ______________ is the least in concentration. creatine

A

Ammonia

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9
Q

Safety glasses, face shields or other eye
protectors must be worn when:

A

working with toxic materials

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10
Q

Observable symptoms of hypoglycemia can be observed when plasma glucose reach this level

A

plasma glucose level ≤55 mg/dL (3.0
mmol/L);

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11
Q

It is a subset of molecular luminescence
spectrometry and measures the amount of light intensity present over a zero
background:

A

Fluorometry

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12
Q

This method is based on the measurement f scattered light and is ideal for quantitative analysis of immunoglobulins:

A

Nephelometry

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13
Q

Serum urea levels drop in severe hepatic diseases, therefore, low BUN is not generally considered abnormal renal function

A

only the second is correct

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14
Q

True of diagnostic specificity, except

A

it generates more true-positive
results

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15
Q

Primary function of serum albumin in the peripheral blood is to

A

maintain colloidal osmotic
pressure

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16
Q

True of the ion-selective electrode, except

A

indirect ISE requires sample
dilution

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17
Q

It refers to the closeness of assayed values

A

Precision

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18
Q

It is known as the rapid serum tube
since clotting of blood would take
place within 5 minutes: pearl white
top

A

Orange top

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19
Q

This hormone which is released from the islet cells of the pancreas inhibits insulin

A

Glucagon

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20
Q

It is the reference method in the
determination of lipoproteins:

A

ultracentrifugation

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21
Q

Before an OGTT is performed, which of the following should be observed?

A

patient should have consumed at least 150 grams/day of carbohydrates for 3 days prior to testing

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22
Q

is the reference method in the
measurement of renal NPNs:

23
Q

It is the only protein with enzymatic activity

24
Q

Earliest NPN to rise in plasma in cases of
kidney diseases:

25
Uniform turbidity in the refrigerated serum indicates elevated concentrations of lipoprotein and lipid:
pre-beta lipoprotein and endogenous triglyceride
26
When serum is mixed with the alkaline picrate reagent and the rate of change in absorbance is measured between 2 points, how do you explain this assay?
Kinetic Jaffe method
27
To avoid interferences caused by biotin in immunoassays, blood should be drawn only after how many hours of not taking that supplement.
48 hours
28
The following are the diagnostic criteria for diabetes mellitus, except:
Point-of-care assay of greater than or equal to 140 mg/dL
29
It determines the components of a sample where the x-axis represents the mass-to-charge (m/z) ratio and the y-axis is their relative abundance within the sample:
mass specrometry
30
It is a gestational marker that is increased in anencephaly and spina bifida:
AFP rev
31
This inflammatory protein marker and APR is included in the biomarkers for COVID-19 due to its reaction to cytokine storm
CRP
32
In electrophoresis, A high ionic strength prevents effective separation of electrophoretic bands while migration of proteins is inversely proportional to molecular size:
both statements are correct
33
These are vital tests in assessing individuals who are at risk of developing coronary artery disease: 1. cholesterol 2. triglycerides 3. phospholipids 4. fatty acids
cholesterol and triglycerides
34
Which of the following is the best choice for decontaminating bench tops spilled with body fluid?
10% sodium hypochlorite
35
In external quality control testing, unknown samples should be processed and treated like a patient sample while the results of the proficiency testing may be shared with other diagnostic laboratories during the period of analysis:
only the first statement is correct
36
It is the recommended fasting hour in most clinical biochemistry tests:
8-12 hours
37
It is described as the chemically cleaned test tube that is designed for the analysis of trace elements:
royal blue top
38
What is the most common cause of trend?
deterioration of reagent
39
How long do we store the saved/processed serum in Chemistry?
7 days
40
What is the main machine/analyer used in Chemistry?
Dimension EXL 200
41
Machine used for Micral test (Microalbumin Test) and HbA1c
DCA Vantage
42
bad cholesterol
LDL
43
good cholesterol
HDL
44
chemical determinations may be of help in establishing the presence of seminal fluid?
Acid phosphatase (ACP)
45
. A hospitalized patient is experiencing increased neuromuscular irritability (tetany). Which of the following tests should be ordered immediately?
Calcium
46
Analysis of CSF for oligoclonal bands is used to screen for which of the following disease states?
Multiple sclerosis
47
When myocardial infarction occurs, the first enzyme to become elevated is
CK
48
The preparation of a patient for standard glucose tolerance testing should include
High carbohydrate diet for 3 days
49
A critical ill patient becomes comatose. The physician believes the coma is due to hepatic failure. The assay most helpful in this diagnosis is:
Ammonia
50
What enzyme catalyzes the conjugation of bilirubin?
Uridine diphosphate glucoronyltranferase
51
What is the anticoagulant of choice for blood gas examination?
Heparin
52
The nitrogenous waste product of nucleic acid or purine metabolism is:
Uric acid
53
Clearance test for urea and creatinine measure:
GFR