CC Flashcards

1
Q

Total CO2 content in arterial blood.

A

19 to 25 mmol/L

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2
Q

In which condition is persistent hypoglycemia seen?

A

Insulinoma & Galactosemia

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3
Q

Sodium in serum is normally with in:

A

136 to 142 mmol/L (135 to 150 mmol/L)

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4
Q

Used as substrate for lipase activity

A

Either olive oil or trioline

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5
Q

Respiratory acidosis includes the following conditions:

A

Hypercapnia
Decrease in pH
Increase in pCO2
Increase of HCO3 as compensatory mechanism

RA - ⬇️ pH; ⬆️ CO2, HCO3

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6
Q

What is the normal partial pressure of CO2 in arterial blood?

A

38 to 42 mmHg

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7
Q

What effect is known as the affinity of hemoglobin for oxygen as affected by pH

A

Bohr’s effect

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8
Q

Tungsten blue product from reduction of phosphotungstic acid by uric acid is measured spectrophotometrically at wave length of:

A

650 to 700 nm

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9
Q

What is considered as the reference method for lipoprotein assay?

A

Ultracenfugation

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10
Q

A hypothetical true value of glucose in a specimen is taken at 5.0 mmol/L. Which analytical value shows accuracy of the test assay?

A

5.0 mmol/L

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11
Q

Using the +/- SD, a technologist is able to decide whether to reject or accept the results of a particular run being in or out of control, with a certainty factors:

A

95%

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12
Q

In which part of the nephron does reabsorption of water, important electrolytes and metabolites primarily occur?

A

Proximal tubules

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13
Q

Dry chemical extinguisher can be used to put off fire caused by the following, EXCEPT:

A

❎ Combustible chemical and metals (D)
✅ Flammable solvents, alcohol, gas (B)
✅ Electrical malfunction as in workings or in equipment (C)
✅ Paper and wood (A)

A - Water
ABC - DC
BC - CO2, Halon

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14
Q

Cretinism in infants is caused by:

A

Hypothyroidism

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15
Q

What is the function of pyridoxal-5-phosphate in the reactions catalyze by the aminotransferases?

A

Prosthetic group

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16
Q

When centrifuging test tubes with serum separator gel, which of the following instruments must be used?

A

Swinging bucket type centrifuge

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17
Q

Which of the following for LDL cholesterol is taken as desirable?

A

125 mg/dL

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18
Q

Condensation reaction of glucose with orthodo-toluidine in hot acidic condition results in final _______________ colored product.

A

Green 💚

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19
Q

In what method is p-nitrophenylphosphate used as a substrate for ALP assay?

A

Bessy-Lowry-Brock and Bowers McComb

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20
Q

The process of separating serum proteins into components by virtue of their net charges in an electric field is known as:

A

Electrophoresis

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21
Q

Bromcresol purple is used in the dye-binding method for:

A

Albumin

22
Q

Repeated and vigorous fist exercise during venipuncture falsely increases the concentration of:

A

Potassium (K+)

23
Q

Which of these are necessary for a patient to undergo oral glucose tolerance test?

A

✅ Diet of at least 150g CHO/day for 3 days
✅ Overnight fasting prior to the test
✅ No strenuous physical activity, smoking nor drinking during the test

24
Q

What is the major precursor substance for the production of bilirubin?

A

Hemoglobin released from aged blood cells

25
Q

Which of the following parameters are decreased in primary hypothyroidism?

A

T4, T3, Resin T3 uptake (Decreased)

*Increased TSH

26
Q

A serum sample shows a chloride concentration of 475 mg per 100 mL, which is the same as:

MW of Cl: 35.5

A

133.8 mEq

(475/35.5)/0.1L

27
Q

In the event of myocardial infarction, which of these enzymes becomes the FIRST elevated in serum?

A

Creative Kinase

  1. CK
  2. AST
  3. LDH
28
Q

What is the molarity of a 10 N sulfuric acid solution?

A

5

N = VM
10 = 2M
M = 5
29
Q

The following are analytical values for Calcium in mg/dL; determine the mean.

  1. 5
  2. 5
  3. 5
  4. 4
  5. 8
  6. 7
  7. 0
  8. 6
  9. 3
  10. 0
A

10.1

30
Q

In adult, hypoglycemia is defined by a plasma glucose level of:

A

< 50 mg/dL

31
Q

Measurement of blood pH and gasses is routinely performed at what temperature?

A

37 deg Celsiues

32
Q

What is the substrate used in the Bessey-Lowry-Brock method for ALP assay?

A

P-nitrophenyl phosphate

33
Q

Majority of the thyroid hormones in blood are bound with:

A

Thyroxine binding globulin (TBG)

34
Q

In order for iron absorbed from the small intestines to be carried in the plasma, it has to be bond by a carrier substance. Which of the following serves this function?

A

Transferrin

35
Q

In HDN, what type of bilirubin is expected to be elevated?

A

Indirect bilirubin

36
Q

Abnormal levels of this electrolyte show very characteristic changes in ECG tracings. Which one is it?

A

Calcium

Ca, K, Mg

37
Q

What reaction is used in the Wroblewski-La Due method?

A

Pyruvate to lactate catalyzed by LDH

WLD - Reverse method for LDH

38
Q

The reagent caffeine sodium benzoate in the Jendrassim Grof method serves for:

A

Accelerator reagent

39
Q

Majority of plasma thyroxine (T4) is:

A

Bound to globulin

40
Q

Tophi that deposit on soft tissue and joints consists of:

A

Sodium urate

41
Q

Which of these antibodies are assoc. with autoimmune thyroiditis?

A

Both microsomal and thyroglobulin antibodies

42
Q

Total bilirubin of an adult female is 12 umol/L and direct bilirubin of about 4 umol/L. The indirect bilirubin is expected to be:

A

Within normal range

43
Q

An enzymatic method used to analyze ethanol measures NADPH from the oxidation of ethanol + NADP. What enzyme catalyzed this reaction?

A

Alcohol dehydrogenase

44
Q

Amylase isormzyme fractionation assay makes used of wheat germ-derived enzyme, which serves to inhibit:

A

Salivary amylase

45
Q

One of the following is not secreted by the anterior pituitary gland (APG). Which one is it?

A

❎ VMA
✅ LH
✅ HGH
✅ ACTH

46
Q

Which of the following forms of exposure places a MT at the highest risk of infection with HIV?

A

Needle stick from AID contaminated needle

47
Q

What enzyme catalyzed the hydrolysis of urea to ammonium ions and bicarbonate?

A

Urease

48
Q
Given the ff. data, determine the carbonic acid level:
pH = 7.07
HCO3 = 8.3 mmol/L
pCO2 = 29.7 mmHg
Delta content = -22.6
A

0.9 mmol/L

H2CO3 = DCO2
DCO2 = pCO2 x 0.031
DCO2 = 29.7 x 0.031
DCO2

49
Q

Hemolysis of serum causes false increase in creatine kinase activity because:

A

Adenylate kinase profuse more ATP or ADP

50
Q

This characterizes the pattern of secretion of creatine kinase in acute myocardial infarction

A

It starts to rise in 6-8hrs after onset, reaches peak in 6-18hrs and returns to normal in 3 days

51
Q

Alkaline phosphatase is increased in both hepatobiliary and bone diseases. (This statement would help make a differential dx)

A

LAP, GGT, and 5’N are increased in hepatobiliary disease ONLY

52
Q

What biochemical substance characterizes as being insoluble in water and in most biological fluid

A

Triglycerides