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CC PROTEINS > CC GNE > Flashcards

CC GNE Flashcards

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1
Q

ultimate end product of protein

A

AMINO ACID

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2
Q

Basic structure of an amino acid

A

amino group
R group
carboxyl group
hydrogen
carbon- central part

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3
Q

enzymes that are responsible for digestion of protein

A

pepsin
trypsin

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4
Q

What is DEAMINATIOM
enzyme for deaminatiom
where do deamination happens

A

Deamination is the removal of amino group
DEAMINASE
kidneys and liver

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5
Q

WHAT IS TRANSAMINATION

A

removal of amino group but will be transferred to a keto acid

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6
Q

these are amino acids that can be converted into glucose

A

glucogenic amino acid

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7
Q

examples of glucogenic AA and its deaminated form

A

alanine- pyrivate
arginine- a ketoglutarate
aspartate- oxaloacetate

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8
Q

amino acids that generates ketone bodies

A

ketogenic AA

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9
Q

what do ketone bodies degrade

A

acetyl-coA

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10
Q

example of ketogenic AA

A

leucine
lysine

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11
Q

differentiate essential AA from non-essential AA

A

essential- come from food
non-essential- naturally made by body

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12
Q

NAME THE ESSENTIAL AMINO ACIDS

A

PVTTIMHALL

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13
Q

fasting for AA

A

6-8 hrs

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14
Q

best anticoag for plasma (AA)

A

Heparin

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15
Q

AA- if analysis cannot be done store in

A

-20- x- 40

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16
Q

Urine is used to (quantify/qualify) level of amino acids?

sample should be collected for

preservative

A

quantify

24 hrs

thymol

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17
Q

what happens when WBCs are elevated

A

affects AA determination (aspartic, glitamic)

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18
Q

absence of phenylalanine hydroxylase

A

PHENYLKETONURIA

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19
Q

what do PAH convert

A

phenylalanine to tyrosine

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20
Q

a drug used to manage PKI

A

Kuvan

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21
Q

semi quantitaive test to determine level of phenylalanine

A

Guthrie

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22
Q

used to quantify conc of phenylalanine

A

HPLC

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23
Q

inhibits break down of tyrosine

A

tyrosinemia

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24
Q

metabolite of tyrosine

A

succinylacetone

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25
Patient has microcephaly and has musty odor urine
Phenylketonuria
26
Most severe. Urine is cabbage like Low levels of Fumarylacetoacetate Hydrolase
Type 1 Tyrosinemia
27
deficiency in tyrosine aminotransferase
Type 2 Tyrosinemia
28
Most rare. Mainly found in liver
Type 3 Tyrosinemia
29
Urine turns brownish black when exposed to air
Alkaptonuria
30
absence of a-ketoacid dehydrogenase
MSUD
31
burnt sugar odor in urine,breathe and skin
MSUD
32
sweaty feet urine odor
ISOVALERIC ANEMIA
33
enzyme required for breaking down of branced AA
a-ketoacid dehydrogenase
34
enzyme involved in the conversion of methionine to cysteine
35
elevated levels of methionine and cysteine in blood and urine cross eyed
Homocystinuria
36
most common form of citrullinemia ASS deficiency
Type 1
37
baby won’t breastfeed baby vomits seizure
type 1 citrullinemia
38
rare type of citrullinemia japanese people
type 2
39
defect in the AA transport system formation of kidney stones
cystinuria
40
small precursors to large molecules
anabolic pathway
41
3 STAGES OF CATABOLIC PATHWAY
DIGESTION ENERGY RELEASE ENERGY STORAGE
42
hormones that promote building up of larger molecules
anabolic hormone
43
higher intake, lower elimination
positive nitrogen balance
44
lower intake, higher elimination
negative nitrogen balance
45
Where do digestion starts
stomach
46
summary of protein digestion
stomach -pancreas- small intestine- liver
47
what will be the net charge if the ph is greater than isoelectric point if the ph is lower than ip
greater- negative lesser- positive
48
level of protein on edematous people
low level
49
2 plasma proteins
albumin globulin
50
long term monitoring of glucose
HbA1c
51
ascending concentration of major plasma protein
pre al albumin a1 a2 hapto transferrin
52
storage of oxygen
myoglobin
53
cardiac marker
myoglobin
54
myoglobin increase on AMI within ____ onset and reaches peak level in ______ hours
2-3 8-12
55
gold standard for acute coronary syndrome
Cardiac troponin
56
level of cTnT that can kndicate myocardial damage
0.1 mg/L
57
adhesive glycoproteins
fibronectin
58
used to predict short term risk of premature delivery
fetal fibronectin
59
accurate marker of CSF leakage
b-trance protein
60
marker for bone resorption
cross linked C-telopeptide
61
marker for GFR
cystatin C
62
differentiates alzheimers from diff forms of dementia
amyloid
63
test for urine proteins
TCA SSA
64
positive result for urine proteins
precipitate
65
reference range for urinary protein
10-250 mg/24 hrs
66
reference values for CSF protein
15-45 mg/dL
67
csf albumin serum albumin ratio
<2.7- 7.3
68
Patient has CSF protein of 10 mg/dL. What possible conditions are associated
hyperthyroidism
69
test used in total nitrogen analysis
chemiluminescence
70
in salt fractionation, what is the supernatant
albumin
71
reference for total protein in ambulatory and recumbent
6.5-8.3 6.0-7.8
72
test to quantify CHON
Kjedahl
73
widely used for protein analysis
Biuret
74
presence of 2 polypeptide in biuret method give what color
violet colored chelate

CC PROTEINS (1 decks)

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