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MUST KNOWS -Mam KATH LANGREO > CC - Plasma proteins > Flashcards

CC - Plasma proteins Flashcards

familiarize with the groups of globulins and their functions (65 cards)

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1
Q

Gamma globulins (6)

A
  1. IgG
  2. IgA
  3. IgM
  4. IgD.
  5. IgE
  6. some CRP: NEGATIVE ACUTE PHASE REACTANTS=Albumin & Trasnferrin
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2
Q

Beta Globulins (7)

A
  1. Pre-Beta Lipoproteins
  2. Beta-Lipoproteins
  3. Transferrin
  4. Hemopexin
  5. Beta2-microglobulin
  6. Complement proteins
  7. C-reactive proteins
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3
Q

Alpha2-Globulins (3)

A
  1. Ceruloplasmin
  2. Haptoglobin
  3. Alpha2-macroglobulin
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4
Q

Alpha1-Globulins(7)

A
  1. Alpha1-antitrypsin
  2. Alpha1-antichymotrypsin
  3. Alpha-fetoprotein (AFP)
  4. Alpha1-acid glycoprotein
  5. Gc-globulin
  6. Thyroxine binding globulin
  7. Alpha-lipoproteins
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5
Q

Globulins (4)

A

Alpha1
Alpha2
Beta
Gamma

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6
Q

measurement of Globulins

A

Globulins = Total Protein - Albumin

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7
Q

marker for malnutrition

A

Pre-albumin / Transthyretin

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8
Q

landmark to confirm if specimen is really CSF

A

Pre-albumin / Transthyretin

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9
Q

Transfers T4 and retinol (vit. A)

A

Pre-albumin / Transthyretin

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10
Q

HIGH values of Pre-albumin

A

Alcoholism
Renal failure
Steroids

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11
Q

most abundant protein

A

Albumin

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12
Q

HIGH values of Albumin

A

Cystic fibrosis

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13
Q

normal value of Albumin

A

3.0 to 5.0 g/dL

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14
Q

osmotic pressure maintenace

A

Albumin

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15
Q

in which group is albumin related?

APR or NAPR

A

Negative Acute Phase Reactant

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16
Q

prevents tissue self destruction

A

A1-antitrypsin

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17
Q

aka alpha1-x

A

Alpha1-antichymotrypsin

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18
Q

Alpha1-antichymotrypsin binds with

A

PSA

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19
Q

protease inhibitor

A

A1-antitrypsin

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20
Q

associated with hepatic and gonodal carcinomas

A

Alpha-Feto protein (AFP)

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21
Q

LOW values of A1-antitrypsin is seen in

A

Emphysema

Juvenile cirrhosis

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22
Q

correlated with acute myocardial infarction and Alzheimer’s disease

A

Alpha1-antichymotrypsin

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23
Q

HIGH values of Alpha-Feto protein (AFP) is seen in

A

Twins
neural tube defects
HDN

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24
Q

LOW values of Alpha-Feto protein (AFP) is seen in

A 
Down Syndrome
Trisomy 18 (Edward's syndrome)
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25
aka Orosomucoid
Alpha1-acid glycoprotein
26
vitamin D and actin affinity
Gc-globulin
27
binds thyroid hormones
Thyroxine binding globulin (TBG)
28
HDL / good cholesterol
Alpha-Lipoproteins
29
vitamin D transporter
Gc-globulin
30
carries progesterone
Alpha1-acid glycoprotein
31
aids in diagnosis of neonatal bacterial infections
Alpha1-acid glycoprotein
32
copper transporter
Ceruloplasmin
33
transports FREE HEMOGLOBIN
Haptoglobin
34
LOW values of Ceruloplasmin is seen in
Wilson's disease(Kayser-fleisher rings), | Menke's Kinky Hair syndrome
35
useful for evaluating intravascular hemolysis esp in HTR and HDN
Haptoglobin
36
alpha2-globulin that has enzymatic activity
Ceruloplasmin
37
LOW levels of Haptoglobin is seen in
Hemolysis | Hemoglobinuria
38
largest, major non immunoglobulin and not excreted in kidneys
(AMG) Alpha2-Macroglobulin
39
10x elevation in Nephrotic syndrome
(AMG) Alpha2-Macroglobulin
40
Pre-Beta-Lipoproteins
VLDL | TAG
41
Beta-Lipoproteins
LDL | Bad cholesterol
42
aka siderophilin
Transferrin
43
binds to heme
Hemopexin
44
light chain component of HLA
B2-Microglobulin
45
for immune response
Complement proteins
46
major B2 fraction component
Transferrin
47
HIGH levels of Transferrin
IDA (Iron Deficiency Anemia)
48
indicator of early hemolysis
Hemopexin
49
present in nucleated cells
B2-microglobulin
50
B2-microglobulin is needed in ____ production
CD8
51
in which group is transferrin related? | APR or NAPR
Negative acute phase reactant
52
dialysis associatedamyloidosis
B2-microglobulin
53
prevents iron loss
Transferrin
54
LOW levels of Complement proteins is seen in
Disseminated intravascular coagulation (DIC) Hemolytic anemia malnutrition
55
HIGH levels of B2-microglobulin
``` SLE RA MM HIV Renal failure ```
56
determines iron-carrying capacity of blood
Transferrin
57
promotes phagocytosis
CRP
58
most abundant gamma globulin
IgG
59
SECONDARY IMMUNE RESPONSE
IgG
60
useful cardiac marker
CRP
61
globulin for allergy anaphylaxis
IgE
62
globulin in mucous secretions
IgA
63
present in surface of B cells
IgD
64
GLOBULIN that is first to appear
IgM
65
Primary immune response
IgM

MUST KNOWS -Mam KATH LANGREO (2 decks)

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