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Therapeutics 3 > CCD and ACS/HF Drug Formulary 2024 > Flashcards

CCD and ACS/HF Drug Formulary 2024 Flashcards

Top 300 Drugs from Sowinski (171 cards)

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1
Q

Amlodipine (Norvasc) Dosing:

A

5-10mg daily
Starting dose: 2.5mg daily

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2
Q

Amlodipine (Norvasc) AE:

A

-Hypotension, flushing, headache, peripheral edema, dizziness, reflex tachycardia

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3
Q

Amlodipine (Norvasc) Monitoring Parameters:

A
  • BP (bc hypotension risk)
  • DI: grapefruit juice, CYP3A inducers/inhibitors
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4
Q

Aspirin (Ecotrin, Valazore) Dosing:

A

for CCD: 81mg daily

for ACS: 325mg chewable ASA loading dose

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5
Q

Aspirin (Ecotrin, Valazore) AE:

A
  • GI/Brain bleed
  • Hypersensitivity
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6
Q

Aspirin (Ecotrin, Valazore) Monitoring Parameters:

A
  • Bleeding
  • Drug interactions: take 12h apart from ticagrelor
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7
Q

Atenolol (Tenormin) Dosing:

A

50-100mg daily
Starting dose: 25-20mg daily

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8
Q

Atenolol (Tenormin) AE:

A
  • Sinus bradycardia, sinus arrest, AV block, reduced LVEF
  • bronchoconstriction
  • fatigue, depression, exercise intolerance, sexual dysfunction
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9
Q

Atenolol (Tenormin) Monitoring Parameters:

A
  • HR
  • CI in bradycardia (HR<50); high deg AV block or sick sinus syndrome
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10
Q

Atorvastatin (Lipitor) Dosing:

A

40-80mg daily (high)

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11
Q

Atorvastatin (Lipitor) AE:

A
  • Muscle pain, darkened urine
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12
Q

Atorvastatin (Lipitor) Monitoring Parameter:

A
  • Get lipid panel
  • Muscle pain, darkened urine
  • Liver function tests
  • Grapefruit juice (1 quart)
  • CI: pregnancy
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13
Q

Benazepril (Lotensin) Dosing:

A

40mg daily/20mg BID
Starting dose: 10mg daily/BID

N/A for HF

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14
Q

Benazepril (Lotensin) AE:

A
  • Dry cough, angioedema, hyperkalemia
  • DI: NSAIDs
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15
Q

Benazepril (Lotensin) Monitoring Parameters:

A
  • Do not use in hypotension/shock, bilateral renal artery stenosis or Hx of worsening of renal function w/ ACE inhibitor/ARB exposure, acute renal failure, or drug allergy/angioedema
  • Check Scr, K, BP, and angioedema
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16
Q

Bisoprolol (Monocor, Zebeta) Dosing:

A

5-10mg daily

For HF:
10mg daily
Initial: 1.25mg daily

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17
Q

Bisoprolol (Monocor, Zebeta) AE:

A
  • Sinus bradycardia, sinus arrest, AV block, reduced LVEF
  • bronchoconstriction
  • fatigue, depression, exercise intolerance, sexual dysfunction
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18
Q

Bisoprolol (Monocor, Zebeta) Monitoring Parameters:

A

-HR
- CI in bradycardia (HR<50); high deg AV block or sick sinus syndrome

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19
Q

Bumetanide (Bumex) Dosing:

A

2mg daily
Starting dose: 0.5mg daily/BID

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20
Q

Bumetanide (Bumex) AE:

A
  • Hypokalemia
  • Hypomagnesemia
  • Hypocalcemia
  • Hyperuricemia
  • Ototoxicity
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21
Q

Bumetanide (Bumex) Monitoring Parameters:

A
  • CI: Sulfa allergy
  • Better in pts w/ CrCl<30ml/min
  • Check K, Mg, Ca levels
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22
Q

Candesartan (Atacand) Dosing:

A

32mg daily
Starting dose: 8mg daily

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23
Q

Candesartan (Atacand) AE:

A
  • Hypotension
  • Hyperkalemia
  • Angioedema
  • GFR reduction
  • fetal pathologies
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24
Q

Candesartan (Atacand) Monitoring Parameters:

A
  • BUN/Scr, K, renal function
  • CI: Hx of angioedema on an ARB, concomitant use of aliskiren in pts w/ DM, pregnancy/breastfeeding
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25
Carvedilol (Coreg) Dosing:
25-50mg BID Starting dose: 6.25mg BID For HF: Coreg - 25-50mg BID Initial - 3.125 BID Coreg CR 80mg daily Initial - 10mg daily
26
Carvedilol (Coreg) AE:
- Sinus bradycardia, sinus arrest, AV block, reduced LVEF - bronchoconstriction - fatigue, depression, exercise intolerance, sexual dysfunction
27
Carvedilol (Coreg) Monitoring Parameters:
- CI in bradycardia (HR<50); high deg AV block or sick sinus syndrome
28
Chlorthalidone (Thalitone, Hygroton) Dosing:
100mg daily Starting dose: 12.5mg daily
29
Chlorthalidone (Thalitone, Hygroton) AE:
- Hypokalemia - Metabolic acidosis - Hyperuricemia - Hypercalcemia - Hyperglycemia - Hyperlipidemia - Sexual dysfunction
30
Chlorthalidone (Thalitone, Hygroton) Monitoring Parameters
- K levels, electrolyte levels, glucose levels, lipid/TG/cholesterol levels - DI: lithium toxicity with concurrent use - CI: sulfa allergy, anuria (can't pee)
31
Clopidogrel (Plavix) Dosing:
75mg daily Loading dose: 300-600mg (none if they took a fibrinolytic + they're above 75 yo)
32
Clopidogrel (Plavix) AE:
- Bleeding (increased when added to ASA) - Diarrhea - Rash
33
Clopidogrel (Plavix) Monitoring Parameters:
- Hold 5 days prior to CABG - Bleed risk
34
Dapagliflozin (Farxiga) Dosing:
10mg daily Starting dose: 5mg daily
35
Dapagliflozin (Farxiga) AE:
- UTIs - Genital fungal infections (gangrene) - Hypotension - Hyperkalemia - Increased cholesterol
36
Dapagliflozin (Farxiga) Monitoring Parameters:
- Do not use in pts with eGFR of <25, unless already on it, then monitor - Do not use if pt is on end-stage renal dysfunction on hemodialysis
37
Digoxin (Lanoxin) Dosing:
0.25mg daily Starting dose: 0.125mg daily
38
Digoxin (Lanoxin) AE:
- Seeing halos (hallucinations) - Dizziness - Headache - Stomach pain
39
Digoxin (Lanoxin) Monitoring Parameters:
- HR, ECGs, BUN/SCr, K, Mg, Ca, serum digoxin levels to watch for toxicity
40
Diltiazem (Cardizem) Dosing:
80-120mg TID Dilt ER: Starting dose: 120-180mg daily Max dose: 360-540mg daily
41
Diltiazem (Cardizem) AE:
- Red. myocardial contractility, bradycardia, hypotension, flushing, headache, dizziness, constipation
42
Diltiazem (Cardizem) Monitoring Parameters:
- CI in HFrEF, bradycardia (HR<50); high deg AV block or sick sinus syndrome (no pacemaker) - Do not use in pts w/ LV dysfunction, increased risk for cardiogenic shock, PR interval >0.24s
43
Empagliflozin (Jardiance) Dosing:
25mg daily Starting dose: 10mg daily
44
Empagliflozin (Jardiance) AE:
- UTIs - Genital fungal infections (gangrene) - Hypotension - Hyperkalemia - Increased cholesterol
45
Empagliflozin (Jardiance) Monitoring Parameters:
- Do not use in pts with eGFR of <30ml/min, unless already on it, then monitor - Do not use if pt is on end-stage renal dysfunction on hemodialysis
46
Enalapril (Vasotec) Dosing:
40mg daily Starting dose: 5mg BID/TID HF: 10mg BID Initial: 2.5-5mg BID 20mg enalapril = 20mg lisinopril = 150mg captopril
47
Enalapril (Vasotec) AE:
- Dry cough, angioedema, hyperkalemia - DI: NSAIDs
48
Enalapril (Vasotec) Monitoring Parameters:
- Do not use in hypotension/shock, bilateral renal artery stenosis or Hx of worsening of renal function w/ ACE inhibitor/ARB exposure, acute renal failure, or drug allergy/angioedema - Check Scr, K, BP, and angioedema
49
Felodipine (Plendil) Dosing:
5-10mg daily Max dose: 20mg daily
50
Felodipine (Plendil) AE:
-Hypotension, flushing, headache, peripheral edema, dizziness, reflex tachycardia
51
Felodipine (Plendil) Monitoring Parameters:
- DI: grapefruit juice, CYP3A inducers/inhibitors
52
Fosinopril (Monopril) Dosing:
40mg daily Starting dose: 10mg daily For HF: 40mg daily Initial: 5-10mg daily
53
Fosinopril (Monopril) AE:
- Dry cough, angioedema, hyperkalemia - DI: NSAIDs
54
Fosinopril (Monopril) Monitoring Parameters
- Do not use in hypotension/shock, bilateral renal artery stenosis or Hx of worsening of renal function w/ ACE inhibitor/ARB exposure, acute renal failure, or drug allergy/angioedema - Check Scr, K, BP, and angioedema
55
Furosemide (Lasix) Dosing:
80mg daily Starting dose: 20mg/dose
56
Furosemide (Lasix) AE:
- Hypokalemia - Hypomagnesemia - Hypocalcemia - Hyperuricemia - Ototoxicity
57
Furosemide (Lasix) Monitoring Parameters:
- CI: Sulfa allergy - Better in pts w/ CrCl<30ml/min
58
Hydrochlorothiazide (Microzide) Dosing:
50mg daily Starting dose: 12.5mg daily
59
Hydrochlorothiazide (Microzide) AE:
- Hypokalemia - Metabolic acidosis - Hyperuricemia - Hypercalcemia - Hyperglycemia - Hyperlipidemia - Sexual dysfunction
60
Hydrochlorothiazide (Microzide) Monitoring Parameters
- K levels, electrolyte levels, glucose levels, lipid/TG/cholesterol levels - DI: lithium toxicity with concurrent use - CI: sulfa allergy, anuria (can't pee)
61
Hydralazine (Apresoline) Dosing:
40-300mg 2-4 times daily
62
Hydralazine (Apresoline) AE:
- Palpitations - Tachycardia - Chest pain - GI SE - Lupus-like rash
63
Hydralazine (Apresoline) Monitoring Parameters:
- Caution with CVA, renal impairment, CAD, liver disease, SLE
64
Irbesartan (Avapro) Dosing:
300mg daily Starting dose: 150mg daily
65
Irbesartan (Avapro) AE:
- Hypotension - Hyperkalemia - Angioedema - GFR reduction - fetal pathologies
66
Irbesartan (Avapro) Monitoring Parameters:
- BUN/Scr, K, renal function - CI: Hx of angioedema on an ARB, concomitant use of aliskiren in pts w/ DM, pregnancy/breastfeeding
67
Isosorbide dinitrate (Isordil, ISDN) Dosing:
Chewable tab: 5-10mg once daily SL tab: 2.5-10mg once daily
68
Isosorbide dinitrate (Isordil, ISDN) AE:
- Headaches - Hypotension - Bradycardia
69
Isosorbide dinitrate (Isordil, ISDN) Monitoring Parameters
- Caution with HOCM, severe aortic stenosis, PDI use
70
Isosorbide mononitrate (Monoket, Imdur, ISMO) Dosing:
20mg BID
71
Isosorbide mononitrate (Monoket, Imdur, ISMO) AE:
- Headaches - Hypotension - Bradycardia
72
Isosorbide mononitrate (Monoket, Imdur, ISMO) Monitoring Parameters:
- Caution with HOCM, severe aortic stenosis, PDI use
73
Labetolol (Trandate) Dosing:
200-400mg BID
74
Labetolol (Trandate) AE:
- Sinus bradycardia, sinus arrest, AV block, reduced LVEF - bronchoconstriction - fatigue, depression, exercise intolerance, sexual dysfunction
75
Labetolol (Trandate) Monitoring Parameters:
- CI in bradycardia (HR<50); high deg AV block or sick sinus syndrome
76
Lisinopril (Zestril) Dosing:
For HF: 20-40mg daily Starting dose: 2.5-5mg daily 20mg enalapril = 20mg lisinopril = 150mg captopril
77
Lisinopril (Zestril) AE:
- Dry cough, angioedema, hyperkalemia - DI: NSAIDs
78
Lisinopril (Zestril) Monitoring Parameters:
- Do not use in hypotension/shock, bilateral renal artery stenosis or Hx of worsening of renal function w/ ACE inhibitor/ARB exposure, acute renal failure, or drug allergy/angioedema - Check Scr, K, BP, and angioedema
79
Losartan (Cozaar) Dosing:
100mg daily Starting dose: 50mg daily/BID
80
Losartan (Cozaar) AE:
- Hypotension - Hyperkalemia - Angioedema - GFR reduction - fetal pathologies
81
Losartan (Cozaar) Monitoring Parameters:
- BUN/Scr, K, renal function - CI: Hx of angioedema on an ARB, concomitant use of aliskiren in pts w/ DM, pregnancy/breastfeeding
82
Metoprolol (Lopressor, Toprol XL) Dosing:
N/A for HF: Lopressor (succinate): 50-100mg BID Toprol XL (tartrate): 100-200mg daily Starting dose: 25-50mg q6-12h For HF: Toprol XL ONLY 200mg daily Initial: 12.5-25mg daily
83
Metoprolol (Lopressor, Toprol XL) AE:
- Sinus bradycardia, sinus arrest, AV block, reduced LVEF - bronchoconstriction - fatigue, depression, exercise intolerance, sexual dysfunction
84
Metoprolol (Lopressor, Toprol XL) Monitoring Parameters:
- CI in bradycardia (HR<50); high deg AV block or sick sinus syndrome
85
Nebivolol (Bystolic) Dosing:
40mg daily Starting dose: 5mg daily
86
Nebivolol (Bystolic) AE:
- Sinus bradycardia, sinus arrest, AV block, reduced LVEF - bronchoconstriction - fatigue, depression, exercise intolerance, sexual dysfunction
87
Nebivolol (Bystolic) Monitoring Parameters:
- CI in bradycardia (HR<50); high deg AV block or sick sinus syndrome
88
Nifedipine (Procardia XL) Dosing:
30-60mg daily Max dose: 120mg daily
89
Nifedipine (Procardia XL) AE:
-Hypotension, flushing, headache, peripheral edema, dizziness, reflex tachycardia
90
Nifedipine (Procardia XL) Monitoring Parameters:
- CI in HFrEF - DI: grapefruit juice, CYP3A inducers/inhibitors
91
Nitroglycerin (SL, Patches, IV) (Nitrostat, Nitro-Dur, glyceryl trinitrate IV) Dosing:
SL Tabs: 0.3-0.6mg PRN, repeat dose up to 3 times every 5 min SL Spray: 0.4mg/spray, repeat dose up to 3 times every 5 min IV NTG: 10mcg/min; titrate by 5mcg/min q5min Patches: 1 patch daily, on 7am, off 7-9pm (not for ACS)
92
Nitroglycerin (SL, Patches, IV) (Nitrostat, Nitro-Dur, glyceryl trinitrate IV) AE:
- Headache (throbbing or pulsating sensation) - Hypotension, dizziness, lightheadedness and facial flushing - Reflex tachycardia
93
Nitroglycerin (SL, Patches, IV) (Nitrostat, Nitro-Dur, glyceryl trinitrate IV) Monitoring Parameters:
- APAP use - Extreme caution with PDEi (potent vasodilators) - Caution with HOCM, severe aortic stenosis, PDI use
94
Olmesartan (Benicar) Dosing:
40mg daily Starting dose: 20mg daily
95
Olmesartan (Benicar) AE:
- Hypotension - Hyperkalemia - Angioedema - GFR reduction - fetal pathologies
96
Olmesartan (Benicar) Monitoring Parameters:
- BUN/Scr, K, renal function - CI: Hx of angioedema on an ARB, concomitant use of aliskiren in pts w/ DM, pregnancy/breastfeeding
97
Omega-3 fatty acid (Lovaza, icosapent ethyl) Dosing:
Lovaza: 2-4gms daily or divided BID Vascepa (icosapent ethyl): 2gm BID w/ food
98
Omega-3 fatty acid (Lovazza, icospent ethyl) AE:
- Fishy breath - Increase bleeding risk
99
Omega-3 fatty acid (Lovazza, icospent ethyl) Monitoring Parameters:
- LDL/TG
100
Prasugrel (Effient) Dosing:
10mg daily
101
Prasugrel (Effient) AE:
- Bleeding (increases life-threatening bleeding compared to clopidogrel) - Diarrhea - Rash
102
Prasugrel (Effient) Monitoring Parameters:
- Hold for 7 days prior to CABG - Bleed risk
103
Propranolol (Inderal LA, Innopran XL, Inderal XL) Dosing:
Inderal: Variable Inderal LA: 80-160mg daily Starting dose: 40mg BID-TID
104
Propranolol (Inderal LA, Innopran XL, Inderal XL) AE:
- Sinus bradycardia, sinus arrest, AV block, reduced LVEF - bronchoconstriction - fatigue, depression, exercise intolerance, sexual dysfunction
105
Propranolol (Inderal LA, Innopran XL, Inderal XL) Monitoring Parameters:
- CI in bradycardia (HR<50); high deg AV block or sick sinus syndrome
106
Quinapril (Accupril) Dosing:
80mg daily Starting dose: 10mg daily/BID HF: 20-40mg BID Initial: 5-10 BID
107
Quinapril (Accupril) AE:
- Dry cough, angioedema, hyperkalemia - DI: NSAIDs
108
Quinapril (Accupril) Monitoring Parameters:
- Do not use in hypotension/shock, bilateral renal artery stenosis or Hx of worsening of renal function w/ ACE inhibitor/ARB exposure, acute renal failure, or drug allergy/angioedema - Check Scr, K, BP, and angioedema
109
Potassium Chloride (Klor Con, KDur) Dosing:
110
Potassium Chloride (Klor Con, KDur) AE:
111
Potassium Chloride (Klor Con, KDur) Monitoring Parameters:
112
Pravastatin (Pravachol) Dosing:
40-80 mg daily (moderate)
113
Pravastatin (Pravachol) AE:
- Muscle pain
114
Pravastatin (Pravachol) Monitoring Parameters:
- Get lipid panel - Muscle pain, darkened urine - Liver function tests - Grapefruit juice (1 quart) - CI: pregnancy
115
Ramipril (Altace) Dosing:
10mg daily OR 5mg BID Starting dose: 2.5mg BID For HF: 5mg BID or 10mg daily Initial: 1.25-2.5mg QD
116
Ramipril (Altace) AE:
- Dry cough, angioedema, hyperkalemia - DI: NSAIDs
117
Ramipril (Altace) Monitoring Parameters:
- Do not use in hypotension/shock, bilateral renal artery stenosis or Hx of worsening of renal function w/ ACE inhibitor/ARB exposure, acute renal failure, or drug allergy/angioedema - Check Scr, K, BP, and angioedema
118
Ranolazine (Ranexa) Dosing:
500-1000mg BID
119
Ranolazine (Ranexa) AE:
- constipation, nausea, dizziness, headache
120
Ranolazine (Ranexa) Monitoring Parameters:
- Do not use with strong CYP3A inhibitors/inducers; limit dose (500mg) w/ mod inhibitors (Dilt, Ver) - Do not use with other drugs that prolong QT interval
121
Rivaroxaban (Xarelto) Dosing:
15-20mg daily with food Also available in 2.5mg BID
122
Rivaroxaban (Xarelto) AE:
- Major hemorrhage - Spinal/epidural hematomas
123
Rivaroxaban (Xarelto) Monitoring Parameters:
- Kidney function
124
Rosuvastatin (Crestor) Dosing:
20-40mg daily (high)
125
Rosuvastatin (Crestor) AE:
- Muscle pain
126
Rosuvastatin (Crestor) Monitoring Parameters:
- Get lipid panel - Muscle pain, darkened urine - Liver function tests - Grapefruit juice (1 quart) - CI: pregnancy
127
Sacubitril/Valsartan (Entresto) Dosing:
Initial: 24mg/26mg BID Max: 97mg/103mg BID daily
128
Sacubitril/Valsartan (Entresto) AE:
- AKI - Angioedema - Hyperkalemia - Hypotension
129
Sacubitril/Valsartan (Entresto) Monitoring Parameters:
- BP - Kidney function - SCr
130
Simvastatin (Zocor) Dosing:
20-40mg daily (moderate)
131
Simvastatin (Zocor) AE:
- Muscle pain
132
Simvastatin (Zocor) Monitoring Parameters:
- Get lipid panel - Muscle pain, darkened urine - Liver function tests - Grapefruit juice (1 quart) - CI: pregnancy
133
Spironolactone (Aldactone) Dosing:
100mg daily Starting dose: 12.5mg daily/BID
134
Spironolactone (Aldactone) AE:
- Hyperkalemia - Hyponatremia - Gynecomastia
135
Spironolactone (Aldactone) Monitoring Parameters:
- Avoid with ACEi/ARBs/Renin inhibitors/ NSAIDS - risk of hyperkalemia - CI: Concomitant use with potassium-sparing diuretics
136
Ticagrelor (Brilinta) Dosing:
90mg BID Loading dose: 180mg
137
Ticagrelor (Brilinta) AE:
- Bleeding - Bradycardia - Heart block - Dyspnea - Ventricular pauses
138
Ticagrelor (Brilinta) Monitoring Parameters:
- Take about 12h apart w/ ASA - Tell Dr. if you experience SOB - Hold 3 days prior to CABG
139
Telmisartan (Micardis) Dosing:
80mg daily Starting dose: 20mg daily
140
Telmisartan (Micardis) AE:
- Hypotension - Hyperkalemia - Angioedema - GFR reduction - fetal pathologies
141
Telmisartan (Micardis) Monitoring Parameters:
- BUN/Scr, K, renal function - CI: Hx of angioedema on an ARB, concomitant use of aliskiren in pts w/ DM, pregnancy/breastfeeding
142
Torsemide (Soaanz) Dosing:
10mg daily Starting dose: 0.5mg daily/BID
143
Torsemide (Soaanz) AE:
- Hypokalemia - Hypomagnesemia - Hypocalcemia - Hyperuricemia - Ototoxicity
144
Torsemide (Soaanz) Monitoring Parameters:
- CI: Sulfa allergy - Better in pts w/ CrCl<30ml/min
145
Valsartan (Diovan) Dosing:
160mg BID Starting dose: 20mg BID
146
Valsartan (Diovan) AE:
- Hypotension - Hyperkalemia - Angioedema - GFR reduction - fetal pathologies
147
Valsartan (Diovan) Monitoring Parameters:
- BUN/Scr, K, renal function - CI: Hx of angioedema on an ARB, concomitant use of aliskiren in pts w/ DM, pregnancy/breastfeeding
148
Verapamil (Calan, Isoptin) Dosing:
60-90mg TID-QID Vera ER: Starting dose: 100-180mg daily Max dose: 400-480mg daily
149
Verapamil (Calan, Isoptin) AE:
- Red. myocardial contractility, bradycardia, hypotension, flushing, headache, dizziness, constipation
150
Verapamil (Calan, Isoptin) Monitoring Parameters:
- CI in HFrEF, bradycardia (HR<50); high deg AV block or sick sinus syndrome
151
Bivalirudin (Angiomax) Dosing:
Bolus: 0.75mg/kg IV Maintenance 1.75mg/kg/hr infusion
152
Bivalirudin (Angiomax) AE:
- Thrombosis - Hemorrhage
153
Bivalirudin (Angiomax) Monitoring Parameters:
- ACR, aPTT, PT/INR, bleeding
154
Captopril (Capoten) Dosing:
For HF: 50mg TID Starting dose: 6.25-12.5mg TID 20mg enalapril = 20mg lisinopril = 150mg captopril
155
Captopril (Capoten) AE:
- Dry cough, angioedema, hyperkalemia - DI: NSAIDs
156
Captopril (Capoten) Monitoring Parameters
- Do not use in hypotension/shock, bilateral renal artery stenosis or Hx of worsening of renal function w/ ACE inhibitor/ARB exposure, acute renal failure, or drug allergy/angioedema - Check Scr, K, BP, and angioedema
157
Enoxaparin (Lovenox, LMWH) Dosing:
Bolus: 30mg IV Maintenance: 1mg/kg sc q12h (15 min after bolus)
158
Enoxaparin (Lovenox) AE:
- Major bleeding - Spinal/epidural hematomas - Thrombocytopenia
159
Enoxaparin (Lovenox) Monitoring Parameters:
- Renal impairment - Platelet count, HgB, HcT, SCr,
160
Eplerenone (Inspra) Dosing:
100mg daily Starting dose: 50mg daily/BID
161
Eplerenone (Inspra) AE:
- Hyperkalemia - Hyponatremia
162
Eplerenone (Inspra) Monitoring Parameters:
- Avoid with ACEi/ARBs/Renin inhibitors/ NSAIDS - risk of hyperkalemia - CI: impaired renal function, T2DM & proteinuria, concomitant use with potassium-sparing diuretics
163
Fondaparinux (Arixtra) Dosing:
Bolus: 2.5mg IV Maintenance: 2.5mg sc q24h
164
Fondaparinux (Arixtra) AE:
- Hypotension - Insomnia - Dizziness - Hypokalemia
165
Fondaparinux (Arixtra) Monitoring Parameters:
- Do not use alone for PCI - CI for CrCl < 30ml/min - CBC, SCr, check stools for bleeding
166
Heparin Dosing:
Initial bolus: 60-80 units/kg Cont. infusion: 12-18 units/kg/hour
167
Heparin AE:
- Major bleeding - Osteoporosis - Thrombocytopenia
168
Heparin Monitoring Parameters:
- HgB, HcT, platelet count, aPTT, bleeding in the stool
169
Prasugrel (Effient) Dosing:
10mg daily Loading dose: 60mg
170
Prasugrel (Effient) AE:
- High bleeding risk
171
Prasugrel (Effient) Monitoring Parameters:
- CI in pts w/ Hx of TIA/stroke - Not recc in pts >75yo <60kg, or a high bleeding risk

Therapeutics 3 (3 decks)

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