CCS Flashcards

1
Q

Quid of DKA criteria (4)

A

blood sugar level > 250 mg/dl
Bicarb < 15
Ketonemia
elevated anion gap

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2
Q

Could Amylase and lipase elevated in DKA

A

yes

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3
Q

Normal bicarb

A

24-30

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4
Q

How to control Anion Gap

A

Na- (Cl +Hco3)

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5
Q

normal anion Gap

A

10-14 meq

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6
Q

criteria for hyperosmolar state(5)

A
glucose more than 600 mg/dl
serum osmolarity more than 330
absent or minimal ketonemia
arterial PH above 7.3
serum bicarb above 20
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7
Q

Mechanism of fluid and electrolytes depletion in HS

A

osmotic diuresis

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8
Q

How to calculate serum osmolarity

A

2Na + glucose/18 + BUN/2.8

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9
Q

Normal serum osmolarity

A

275-295

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10
Q

normal arterial PH

A

7.35-7.45

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11
Q

corner stone of DKA treatment (3)

A

Hydration
Insulin
Potassium replacement

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12
Q

Hydration urgency phase in DKA (3)

A

1-2 liters in bolus
500 ML per hour during first 4 hours
continue with 250 ml for several hours

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13
Q

second phase of hydration in DKA if no signs of dehydration

A

continue with 1/2 NS 250-500 cc per hour for 3 to 4 hours

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14
Q

volume repletion in DKA

A

4 to 10 liters

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15
Q

What to do in DKA when glycemia is < ou egal a 250

A

DW 5 or 10%

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16
Q

How to give insulin

A

O,1 U/kg en bolus followed by 0,1 U/kg per hour in continuous infusion

17
Q

Potassium replacement in DKA criteria (3)

A

K < 5.3
No EKG changes
Normal renal function

18
Q

what about Bicarb and phosphore replacement

A

no evidence of clinical relevance

19
Q

Quid of ABCD

A

Airway
breathing
circulatory
drugs

20
Q

Airway quid (3)

A

Airway suction
give O2
Pulse oxymetry

21
Q

Quid of Breathing

A

Endotracheal intubation

22
Q

criteria for endotracheal intubation (3)

A

If you cannot protect the airway
No improvement with nasal or face mask o2
pao2 < 55 or Paco2 > 50

23
Q

quid of C

A

IV access
Cardiac monitoring
foley
Obtain a finger stick glucose

24
Q

Quid of D (3)

A

drugs if unconscious without trauma
give thiamine
Naloxone
Dextrose 50%

25
Q

Narcotic overdose signs(2)

A

Hypotension

Pinpoint pupils

26
Q

Why hypotension in narcotic overdose

A

Peripheral vasodilation

27
Q

treatment of narcotic overdose

A

Naloxone

Activated charcoal if intoxication comes from ingestion

28
Q

clue indicating hemolytic anemia (3)

A

Jaundice with indirect bilirubin predominant
Bite cells on peripheral smear
Anemia

29
Q

intravascular hemolysis cause

A

IGM causing destruction by IGM

30
Q

Extravascular hemolysis cause

A

IGG causing GR destruction using Macrophages in spleen or liver

31
Q

Lab: intravascular hemolysis (3)

A
Hemoglobinuria
High LDH
Low haptoglobin
shistocytes , helmet cells or fragmented red blood cells on Peripheral smear
High reticulocytes count
32
Q

Peripheral smear in intravascular hemolysis (3)

A

shistocytes
helmet cells
fragmented red blood cells

33
Q

Lab in extravascular hemolysis

A
Increased indirect bilirubin
high LDH
low haptoglobin
spherocytes 
High reticulocyte count
34
Q

Peripheral smear in Extravascular hemolysis

A

spherocytes

35
Q

Why low haptoglobin

A

Haptoglobin is a transporter of protein, transports newly released indirect bilirubin and is rapidly used up in hemolysis