CCSET2 Flashcards

(44 cards)

1
Q

What does the sweep gas flow on an ECMO circuit affect?

A

CO2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the clinical and laboratory signs associated with LVAD pump thrombosis?

A

Rising LDH level, increasing power output on the device, worsening heart failure sx and evidence of hemolysis (high LDH, low haptoglobin, anemia)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

In an LVAD, what is pump power?

A

The number of watts required by the device to pump blood at the required RPM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the classic triad of antimalarial overdose? Also seen with what medicine?

A

Hypotension, hypokalemia, and QTc prolongation; hydroxychloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are some basic steps to prevent having a retained guidewire?

A

Don?t go too deep; 20 cm is sufficient, maintain contact with the wire the whole time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What does APRV stand for? Where does most of the pressure go to in the lung?

A

Airway Pressure Release Ventilation; most goes to areas of lung that are already recruited which is somewhat of an issue but that?s kind of always the case

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What 3 classes of antibiotics should be avoided in myasthenia gravis? Why?

A

Quinolones, macrolides, and aminoglycosides (affect transmission across the neuromuscular jxn); cephalosporins are safe

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is the expected rise in PCO2 for a metabolic alkalosis?

A

The PCO2 should rise by 0.7 for every 1 increase in HCO3 (for acidosis it is 1 of HCO3 for every 10 mmHg PCO2 acutely and 3-4 chronic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How do simple pleural effusions and complex pleural effusions look on US?

A

Simple = black and anechoic fluid; complex pleural effusions have echogenic debris (i.e. empyema and parapneumonic effusions)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is QB and QD on a dialysis machine?

A

QB = blood flow; QD = dialysate flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

How does a Stent Graft Collapse present in a pt with TEVAR?

A

With distal aortic occlusive symptoms; i.e. leg weakness and no pulses etc.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

A retained guidewire is most common at what anatomic location?

A

Femoral; probably bc these are done more emergently and no XR done afterwards.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the best way to manage pulmonary edema in a patient with CHF w/ HTN emergency?

A

Improve the BP to decrease the afterload (as the cause is increased afterload, diuretics not as helpful here)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

In DKA, what do you do when the glucose is <200?

A

Decrease the rate of the insulin gtt (is usually 0.1-0.14 u/kg/hr) so go to 0.02-0.05 u/kg/hr and switch to D5 1/2S until the AG normalizes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

When should potassium be added to the fluid for DKA?

A

Add 20-30 mEq of KCl once the K is <5.2 (or if that?s what it is on the original lab draw)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What should be on the DDx if thinking about septic emboli in pt with oropharyngeal problems (aside from endocarditis)

A

Lemierre syndrome- septic thrombophlebitis of IJ w/ Fusobacterium necrophorum; often with pulmonary infiltrates 1st line - pip/tazo or amp/sulbactam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

A bite from a Lone Star tick may cause what issue with food in the future?

A

Red Meat Allergy- it’s weird but on the rise; IgE mediated anaphylaxis against an epitope of mammalian oligosaccharide galactose-alpha-1,3-galactose

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the difference between phentolamine and phenoxybenzamine?

A

Phentolamine is a rapid acting alpha blocker and phenoxybenzamine is a long acting alpha blocker

19
Q

What should the initial IVF rate be for patients with DKA/HHS?

A

15-20 cc/kg/hr (prob get a couple boluses too) so that?s like 150-200 for a 100 kg person

20
Q

If you think that someone has a pump thrombosis of their LVAD what should you do next?

A

Start heparin gtt (this text says to DC warfarin as well in preparation for explantation)

21
Q

For an acute respiratory acidosis, what is the expected increase in serum bicarbonate?

A

Increase by 1 for every 10 mmHg PCO2 is above 40 (normal PCO2 = 40, normal bicarb = 25)

22
Q

What serologic test can help to diagnose myasthenia gravis?

A

Acetylcholine receptor antibodies

23
Q

What are the modalities to diagnose ischemic colitis?

A

Often they start with AXR (may show thumbprinting) but really you need a colonoscopy; contrast CT can help but not if AKI which is often present given the mechanism of ischemic colitis is HoTN

24
Q

When do patients with DKA need bicarbonate?

A

If pH is less than 6.9

25
In an LVAD, what is the pulsatility index?
the difference between maximal and minimal flows divided by the average flow of each cardiac cycle
26
What may happen in an LVAD if the preload is low or if the pump speed is too high?
May develop a suction event; can try bolusing IVF or decreasing the pump speed to increase LV filling and decrease the suction event
27
What is the corrected sodium for pseudohyponatremia?
1.6 for every 100 of glucose above 100
28
What is the chronic compensation of bicarb for chronic respiratory acidosis?
3-4 for every 10 mmHg above 40 for the PCO2; in acute resp acidosis it is 1 for every 10
29
What should you do in LVAD patients in whom there is either a decrease in pulsatility index or pump speed?
This is a cue to evaluate; may be in an arrhythmia like VT/VF which can lead to less flow and suction event; consider TTE, try decreasing speed more and give IVF
30
What did the HEAT trial evaluate?
The utility of giving acetaminophen vs. no acetaminophen for fevers in the ICU; no difference seen in number of ICU days in the two groups
31
When is the incidence of pump thrombosis in LVAD the greatest?
Within the first 6 months of placing the LVAD
32
How do you diagnose SLE mediated DAH?
Pretty much clinically with diffuse pulmonary infiltrates and progressively bloodier BAL fluid samples (Tx with steroids and cyclo or rituxan --\>PLEX)
33
What effect does a decrease in pump speed on an LVAD have on the LV filling time?
There will be increased LV filling time given that the blood is flowing out at a slower rate
34
What drugs have been associated with the development of red meat allergy? What infectious diseases?
Cetuximab and things from porcine sources; Lone Star tick bites
35
What should you think in an LVAD pt who has a rising LDH, evidence of hemolysis, and new/worsening heart failure symptoms?
Pump thrombosis
36
If you are giving inotropic support to someone with a heart failure exacerbation, what medication should you discontinue?
Beta blockers, seems obvious but could forget
37
If a person on VV ECMO starts to have hemodynamic instability what sorts of things should be in mind?
Barring circuit rupture it doesnt have to do with the flow because VV (no VA) ECMO doesnt really affect cardiac output; so you want to think about like RP bleed etc esp. bc pts on ECMO are anticoagulated
38
What is the most common LVAD in the US? Where is the inflow cannula and outflow cannula?
Heartmate II; Inflow cannula in LV apex; outflow cannula in aorta; magnetic field rotates between 6-15,000 RPM to get continuous flow up to 10 L/min
39
What is the only variable that is programmable by the operator for an LVAD?
Pump speed (other values: power, flow, and pulsatility all depend on the pt physiology)
40
What happens to LVAD numbers in a suction event?
Pulsatility index will drop because the pump flow decreases; then it will automatically go to the low speed limit set by the operator (remember: pump speed is the only variable programmable by the operator)
41
On an ultrasound of the lung what will alveolar consolidation (i.e. pneumonia) look like?
Should look a lot like liver
42
What is the basic mgmt of DKA/HHS?
Need to give lots of IVF (Rate is 15-20 cc/kg/hr). Give a bolus of 0.1 u/kg insulin and follow by gtt of 0.1-0.14 u/kg/hr; if pH \<6.9 give bicarb and if K \<5.2 add 20-30 mEq KCl to IVF? Once glucose less than 200 decrease insulin to 0.02-0.05 u/kg/hr until AG normalizes and have them on D5 1/2S.
43
The ADA consensus on DKA and HHS suggests that pts should get what bolus and what infusion rate of insulin?
0.1 u/kg bolus followed by either 0.1-0.14 u/kg/hr; a retrospective study showed that only 20% of academic centers were compliant with this
44
What parameter on VV or VA ECMO affects CO2?
Sweep Gas Flow