Cell Biology Flashcards

1
Q

Homeostasis is…

A

Involuntary neuronal and hormonal control of the body environment to keep all physical parameters within normal limits

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2
Q

Total body water =

A

0.6 x body weight

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3
Q

Extracellular water is … of total body water

A

1/3

3/4 interstial and 1/4 plasma

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4
Q

Which ion is higher in intracellular fluid?

A

Potassium

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5
Q

Diffusion

A

Solute movement from a higher concentration to a lower concentration

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6
Q

Osmotic pressure

A

Concentration gradient caused by unequal distribution of ions across a semi-permeable membrane causing water to move towards the high electrolyte concentration
Keeps water in the blood vessel

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7
Q

Oncotic pressure

A

Concentration gradient caused by unequal distribution of macro-molecules across a membrane
Keeps water in the blood vessel

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8
Q

Which pressure is greater? Why?

A

Oncotic pressure is greater than osmotic pressure as proteins are much larger than water and have a greater water pull than ions

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9
Q

Why is water attracted to ions?

A

When water is formed, oxygen pulls electrons from hydrogen ions, creating a positive pole and a negative pole.
1 molecule of water will bind 1 sodium or potassium ion.
= dissolving.

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10
Q

Hydrostatic pressure

A

Pushes water out of the blood vessel

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11
Q

Blood pressure in the capillary

A
  1. Hydrostatic pressure from arties is high - forces fluid out
  2. Hydrostatic pressure drops over length of capillary
  3. By the time blood reaches veins, hydrostatic pressure is lower than oncotic pressure, so fluid is reabsorbed into blood
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12
Q

Factors causing extravasation (fluid movement out of blood vessel) (4)

A

Increased BP
Blocked Lymph drainage
Inflammation
Liver failure

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13
Q

Factors causing fluid retention (2)

A

Hypernatremia (too much sodium)

Renal failure

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14
Q

Chemical communication in the body

A
  1. Stimulus
  2. First messenger (hormone or neurotransmitter)
  3. Receptor
  4. Secondary messenger (change how cell responds)
  5. Inhibitory or excitatory action
  6. Cellular response
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15
Q

Negative feedback

A

Most common form of feedback
Normally, neurotransmitter is released from nerve ending and binds to target
Negative feedback is when neurotransmitter binds to pre-synaptic nerve, inhibiting more neurotransmitter release

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16
Q

Positive feedback

A

Found when the body wants to liberate something, e.g. giving birth, defecation

17
Q

Giving birth - positive feedback loop

A
  1. Cervix dilation
  2. Stretch receptors in cervix fire
  3. Hypothalamus
  4. Posterior pituitary releases oxytocin
  5. Acts on uterine muscle causing contractions
  6. Forces baby through cervix - greater stretch