cell cycle Flashcards

1
Q

what is the purpose of cell division?

A

cell division is essential for organism creation, growth and repair. it allows multicellular organisms to function normally and enables unicellular organisms to produce identical offspring

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2
Q

what are the main phases of the cell cycle?

A

G1 - growth phase where cell synthesises proteins and prepares for dna replication. S phase - dna replication. G2 phase - duplicated chromosomes are checked for error. mitotic phase - nuclear division and cytokinesis

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3
Q

what are the phases of mitosis?

A

prophase, prometaphase, metaphase, anaphase, telophase

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4
Q

which phases of the cell cycle make up interphase?

A

G1, S and G2

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5
Q

what is the function of the G1 checkpoint?

A

the cell commits to cell cycle entry and chromosome duplication. checks for nutrients, growth factors and DNA damage

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6
Q

what is the function of the G2 checkpoint?

A

triggers early mitotic events leading to metaphase. checks for cell size and dna replication

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7
Q

what is the function of the metaphase to anaphase checkpoint?

A

stimulates sister chromatid separation, completing mitosis and cytokinesis. checks for chromosome spindle attachment

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8
Q

what are the main mechanisms that regulate Cdk activity?

A

cyclins, Cdk activating kinases (CAK), regulatory inhibitory phosphorylation (Wee1), Cdk inhibitory kinases (CKIs)

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9
Q

what is the function of cyclin dependent kinases?

A
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