Cell Cycle and Mitosis Flashcards

1
Q

What is the purpose of mitosis?

A

to enable cells t generate new, genetically identical cells for growth and replacement

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2
Q

How many chromosomes do humans have?

A

46 chromosomes, 23 pairs

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3
Q

Haploid and Diploid

A

Haploid (n): 1 set of chromosomes, 23 total

Diploid (2n): 2 sets of chromosomes, 46 total

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4
Q

Centromeres

A

sequence of DNA; cohesion proteins bind each centromere of each sister chromatid

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5
Q

Kineticore

A

where microtubules bind on a chromosome

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6
Q

Interphase

A

G1: cell size and protein content increase, cell size doubles
S: when DNA replicates
G2: all organelles duplicate, synthesize microtubules, cell becomes organized

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7
Q

The spindle

A

composed of proteins (most microtubules), spindle fibers connect at each pole to the centriole

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8
Q

Prophase

A

condensed chromosomes, nucleus intact, centrosomes migrate to polls forming spindle

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9
Q

Prometaphase

A

nuclear envelope is gone, microtubules attach, chromosomes begin to move to center of cell

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10
Q

Metaphase

A

alignment of chromosomes along metaphase plate

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11
Q

Anaphase

A

starts when centromeres split, cohesion proteins are removed from all chromosomes, sister chromatids are pulled to opposite poles

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12
Q

Telophase

A

spindle disassembles, nuclear envelopes form, nucleolus reappears and chromosomes begin to uncoil

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13
Q

Cytokinesis

A

cells split into equal halves (via cleavage furrow), actin polymerizes forming an actin contractile ring to split cells

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