Cell cycle (cytokinesis) Flashcards

(42 cards)

1
Q

final stage in the cell cycle

A

cytokinesis

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2
Q

division of the cytoplasm in two.

A

cytokinesis

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3
Q

some cells undergo ____without cytokinesis and thereby acquire multiple nuclei.

A

mitosis

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4
Q

The first visible change of cytokinesis in an animal cell

A

appearance of a pucker, or cleavage furrow

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5
Q

The structure underlying furrow process

A

contractile ring

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6
Q

As the sister chromatids separate in anaphase, ____ and _____ II begin to
accumulate in the rapidly assembling
contractile ring

A

actin and myosin II

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7
Q

depends on formin (parallel arrays of
linear, unbranched actin filaments)

A

local formation of actin filaments

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8
Q

overlapping arrays of actin and myosin II
filaments ___ to generate the force
that divides the cytoplasm in two

A

contract

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9
Q

persists as a tether between
the two daughter cells and contains the
remains of the central spindle

A

midbody

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10
Q

a large protein structure derived from
the antiparallel interpolar microtubules
of the spindle midzone, packed tightly
together within a dense matrix material

A

central spindle

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11
Q

small GTPase of the Ras superfamily

A

RhoA

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12
Q

controls the assembly and function of the
contractile ring at the site of cleavage

A

RhoA

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13
Q

RhoA promotes:

A

actin filament formation, myosin II
assembly, and ring contraction at the cell
cortex

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14
Q

RhoA stimulates actin filament formation by

A

activating formins; activating multiple protein
kinase (Rock)

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15
Q

must occur only after the two sets of
chromosomes are fully segregated from each other

A

Cytokinesis

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16
Q

must be placed
between the two sets of daughter
chromosomes

A

site of division

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17
Q

depend on
mitotic spindle

A

correct timing and position

18
Q

during anaphase, the spindle generates
signals that initiate ____ formation at a
position midway between the ____
___

A

furrow
spindle poles

19
Q

Why cytokinesis also occurs
at the correct time

A

because dephosphorylation of Cdk substrates, which depends on cyclin destruction in metaphase and anaphase, initiates cytokinesis

20
Q

How does the mitotic spindle specify the site of division?

A
  1. astral stimulation model
  2. central spindle stimulation model
  3. astral relaxation model
21
Q

astral microtubules carry furrow-inducing
signals

A

astral stimulation model

22
Q

the spindle midzone, or central spindle,
generates a furrow
-inducing signal that
specifies the site of furrow formation at
the cell cortex

A

central spindle stimulation model

23
Q

the astral microtubules promote the
local relaxation of actin
–myosin bundles
at the cell cortex

A

astral relaxation model

24
Q

cortical relaxation is minimal at the
spindle equator; promoting cortical
contraction

A

astral relaxation model

25
higher-plant cells are enclosed by a semirigid
cell wall
26
the cytoplasm of the plant cell is _____from the ____out by the _____ __ _ ___ ___ ____, called the cell plate, between the two daughter nuclei
partitioned inside construction of a new cell wall ( cell plate)
27
The assembly of the cell plate begins in
late anaphase and is guided by a structure called the phragmoplast
28
contains microtubules derived from the mitotic spindle
phragmoplast
29
each daughter cell must also inherit all of the other essential cell components, including the membrane-enclosed organelles
process of mitosis
30
can arise only by the growth and division of the preexisting organelles.
organelles
31
usually present in large enough numbers;their numbers double once each cycle
mitochondria and chloroplasts
32
cut into two during cytokinesis
ER
33
reorganized and fragmented during mitosis
Golgi apparatus
34
cells divide asymmetrically to produce two cells that ____ in size, in the cytoplasmic contents they inherit, or in both
different
35
the mother cell must first segregate ___ _____ _______ to one side of the cell and then position the ___of ____ so that the appropriate daughter cell inherits these components
cell fate determinants plane of division
36
Some cells undergo multiple rounds of nuclear division without intervening _____ division.
cytoplasmic
37
first 13 rounds of nuclear division occur without cytoplasmic division
Drosophila embryo
38
A cell in which multiple nuclei share the same cytoplasm is called a
syncytium
39
greatly speeds up early development
syncytium
40
membranes are created around each nucleus in one round of coordinated cytokinesis
cellularization
41
Nuclear division without cytokinesis in some types of mammalian cells
megakaryocytes, hepatocytes, heart muscle cells
42