Cell Division [Mitosis] Flashcards
(21 cards)
What is the main purpose of mitosis?
Growth & Repair
What can mitosis produce from a single parent cell?
Two genetically identical daughter cells (single haploid cell (n) or diploid cell (2n) divides into two haploid or diploid daughter cells that are same as parent.)
In what type of cells does mitosis occur? What does it mean?
Somatic cells, meaning all cells in the body except for the reproductive cells
Is there a reduction in the number of chromosomes during mitosis?
No
Why is mitosis important?
- Growth & development of multicellular organisms
- Repair & maintenance of damaged tissues (cut/injury)
- Asexual Reproduction of some organisms
What happens during G1 Phase in mitosis interphase?
- Cell size doubles due to active metabolic activity
- Replication of organelles
What happens during S-Phase in mitosis interphase?
- DNA replication
What happens during G2 Phase in mitosis interphase?
- Enzymes for cell division are produced
What are the 4 main phases of mitosis?
PMAT: Prophase, Metaphase, Anaphase, Telophase
What happens during mitosis prophase?
- Chromosomes condenses (2 sister chromatids, held together at the centromere)
- Mitotic spindle begins to form from the centrioles as cytoskeleton disassemble
- centrioles migrate to opposite poles
- Nucleolus breaks down
- Chromosomes kinetochore attach to microtubules from each pole
What happens in mitosis metaphase?
- All chromosomes align at the metaphase plate (center of the nucleus)
What happens in mitosis anaphase?
- The chromosomes break apart
- Sister chromatids move to the opposite ends of the cell
- Microtubules not attached will elongate and push apart, separating the poles and making the cell longer.
What happens in mitosis telophase?
- Cleavage furrow develops, made from contractile ring
- Chromosomes decondense and return to their ‘stringy’ form
- Two new nuclei forms
- Nuclear membranes and nucleoli reappear.
- Spindle apparatus breaks down to its building blocks
What happens to plant cells in mitosis telophase?
- Vesicles form an expanding membrane partition (cell plate)
What happens in mitosis cytokinesis?
- Division of cytoplasm
What is the shortest phase?
Metaphase
Why are checkpoints established during the cell cycle?
- Ensures the process is occurring accurately
- Prevents unregulated cell division, causes cancer (forms a lump)
Where are the cell division checkpoints located and what are their main function?
- G1/S Checkpoint - tells whether cell cycle continues or stops
- G2/M Checkpoint - allows mitosis
- Spindle Checkpoint - ensures that all chromosomes have attached to a spindle
What are the contributing factors in cell cycle?
- Growth factors
- Size of cell
- Nutritional state of cell
How long does mitosis typically take?
24 hours
What happens to cells that do not divide?
- Die
- Take a specialized role (brain neuron)