cell junctions

Question 1

explain how a focal adhesion (cell-ECM) works?

Answer 1

cell has talin - the hemidesmosome, then integrin connects this to the fibronectin of the ECM.

Question 2

what are cell-cell (cadherens) junctions like?

Answer 2

connects cell to cell, cell- actinin - desmosome-cadherin - desmosome - actinin - cell. cadherin is Ca2+ dependent. uses a-actinin not talin to connect to cellular matrix

Question 3

what are channel forming junctions?

Answer 3

a junction between cells that allows small soluble molecules to pass through from one cell to another neighbouring cell

Question 4

what is the adhesion belt?

Answer 4

Adhesion belt, commonly known as the intermediate junction, refers to the formation of a continuous band-like structure between adjacent cells. The interaction of actin and cadherin forms an adhesion belt that binds two cells