Cell Metabolism 1 Flashcards
(19 cards)
What are Anabolic Reactions?
Make larger molecules from smaller ones
What are Catabolic Reactions?
Produce smaller molecules from larger ones
What does an oxidation-reduction reaction involve?
Electron transfer
What does a ligation reaction requiring ATP cleavage involve?
Formation of Covalent Bonds
What do Isomerisation reactions involve?
Atom rearrangement to make isomers
What do group transfer reactions involve?
Transferring functional groups
What do hydrologic reactions involve?
Cleavage of bonds by addition of Water
What do addition/removal of functional group reactions involve?
Addition of functional groups to double bonds or removal to form double bonds
Where does glycolysis take place in mitochondria?
Cytoplasm
Outline 1st glycolysis step
Glucose → Glucose-6-Phosphate + H+
Catalysed by Hexokinase
ATP → ADP
Group Transfer Reaction
Outline 2nd Glycolysis Step
Glucose-6-Phosphate ➡️ Fructose-6-Phosphate
Phosphoglucose Isomerase
Isomerisation
Outline the 3rd Glycolysis Step
Fructose - 6 - phosphate ➡️ fructose - 1,6 - bisphosphate
Phosphofructokinase
ATP ➡️ ADP
Group Transfer
Outline the 4th Glycolysis Step
Fructose-1,6,-Bisphosphate ➡️ Glyceraldehyde 3-Phosphate + Dihydroxyacetone Phosphate
Aldolase
Hydrolytic
Outline 5th Glycolysis Step
Dihydroxyacetone Phosphate ➡️ Glyceraldehyde 3-Phosphate
Triose Phosphate Isomerase (TPI)
Isomerisation
Outline 6th glycolysis step
2 x Glyceraldehyde 3-Phosphate ➡️ 1,3-Bisphosphoglycerate
Glyceraldehyde 3-Phosphate Dehydrogenase
NAD+➡️NADH
Redox + Group Transfer
Outline 7th Glycolysis Step
1,3-Bisphosphoglycerate ➡️ 3-Phosphoglycerate
Phosphoglycerate Kinase
ATP ➡️ ADP
Group Transfer
Outline 8th Glycolysis Step
3-Phosphoglycerate ➡️ 2-Phosphoglycerate
Phosphoglycerate Mutase
Isomerisation
Outline 9th Glycolysis Step
2-Phosphoglycerate ➡️ Phosphoenolpyruvate + Water
Enolase
Group Removal/Dehydration
Outline 10th Glycolysis Step
Phosphoenolpyruvate ➡️ Pyruvate
Pyruvate Kinase
ADP ➡️ ATP
Group Transfer
