Cell SF Exam 1 Flashcards

(50 cards)

1
Q

4 classes of macromolecules

A

protiens, carbohydrates, nucleic acid, lipids

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2
Q

____ controls bilayer rigidity and H2O permeability

A

cholesterol

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3
Q

transmembrane amino acids are (polar/nonpolar)

A

nonpolar

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4
Q

Is the bilayer symmetrical?

A

No

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5
Q

A uniporter moves one molecule (up/down) the gradient

A

down

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6
Q

____ are the fastest membrane transport proteins

A

ion channels

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7
Q

what triggers a shape change in a uniporter?

A

R group

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8
Q

process using uniporters is sometimes called _____ diffusion.

A

facilitated

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9
Q

Type of membrane transport involved in both active and passive transport

A

cotransporters

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10
Q

type of membrane transport where the energy from passive transport is used for active transport

A

cotransporters

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11
Q

secondary active transport

A

energy from passive transport is used in active transport

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12
Q

cotransporter where molecules are moving in opposite directions

A

antiporter

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13
Q

cotransporter where molecules are moving in the same direction

A

symporter

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14
Q

Na+ is ____ outside the cell and ____ inside the cell

A

high, low

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15
Q

K+ is ___ outside the cell and ___ inside the cell

A

low, high

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16
Q

Ca2+ is ____ outside the cell and ____ inside the cell

A

high, low

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17
Q

Sodium potassium ATPase

A

uses energy of ATP hydrolysis to move both Na+ and K+ against gradient

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18
Q

For every ___ K+ moved into the cell, ___ Na+ moves out to depolarize

A

2, 3

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19
Q

The inside of a cell is ___ charged in comparison to the outside

A

negatively

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20
Q

Impermeate anion effect

A

a particle that cant cross the membrane because of its charge

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21
Q

3 major categories of electrically excitable cells

A

muscle, endocrine, nerve

22
Q

when the inside of the neuron gets more positively charged this is called ____

A

depolarization

23
Q

Neurotransmitters bind to ______ to start the domino effect of depolarization

A

Ligand gated Na+ channels

24
Q

Does Na+ channel or K+ channel open faster?

25
Enzymes
Proteins that are catalysts
26
Catalyst
Substance that changes the rate of a reaction without being consumed in the reaction (not a reactant or product)
27
Do catalysts provide energy to a reaction or change delta G?
no
28
Catalysts speed up a reaction that would have otherwise already occured (T/F)
true
29
Cofactors
Non protein component of an enzyme (may also be called prosthetics)
30
Allosteric regulator
binds enzyme (not at active site) and changes the shape of the active site
31
An enzyme that is noncompetitive and reversible, and binds somewhere other than the active site can also be called
allosteric inhibition
32
Cells within the same tissue communicating with one another through extracellular fluid
Paracrine signaling
33
3 general function classes of receptors at the plasma membrane
ligan gated ion channels, enzyme coupled receptors, G protein coupled receptors
34
2nd messengers act as
allosteric regulators
35
flow from ligand to 2nd messenger
Ligand + receptor>> complex>> activates transducer>> activates effector>> makes 2nd messenger
36
the job of the effector is to make the
2nd messenger
37
Pka consists of 4 subunits:
2 R-subunits and 2 C-subunits
38
The effector that is the enzyme that catalyzes the production of ____
cAMP
39
an enzyme that transfers a phosphate from ATP to a protein
kinase
40
an enzyme that removes a phosphate from a protein
phosphatase
41
what is it called when a phosphate group is removed from protein
dephosphorylates
42
when a phosphate is moved from ATP to a protein
phosphorylation
43
______ is an enzyme that catalyzes the production of cAMP.
adenyl cyclase
44
The alpha subunit does what
hydrolyzes GTP to GDP
45
alpha-GDP is (active/inactive)
inactive
46
alpha-GTP is (active/inactive)
active
47
The thing that turns off the G protein is
hydrolysis of GTP back to GDP
48
the 2nd messenger (cAMP) turns on____ which then turns on
PKA, GPK
49
PKA bound to the second messenger turns off _____
glycogen synthase
50
the target protein changes shape based on whether or not it is _____
phosphorylated