Cell Surface Mebrane Flashcards
(10 cards)
Role of membranes
- control the exchange of materials they are partiall permeable
- form compartments within cells
- play role in cell signalling by acting as an interface for communication between cells
Why is the fluid mosaic model called the fluid mosaic model
Described as fluid because
- phospholipid and proteins can move around
- Phospholipid move sideways within own layer
Described as mosaic because
- scattered pattern produced by the proteins within the phospholipid bilayers looks like mosaic
What does the fluid mosaic model helps to explain and what is it composed off
Cell signalling
Cell to cell interactions
Passive and active movement
Composed of
Phospholipid, cholesterol, glycoproteins and glycolipids and transport proteins
Glycolipid and glycoproteins
Exists on surface which enables them to act as receptors molecules by binding substances at cell surface
Act as 3 main receptors
- signalling receptors
- receptor involved in endocytosis
- receptor involved in cell adhesion and stabilisation
Acts as antigens for cell to cell recognition
Transport proteins
Create hydrophilic channels to allow ions and polar molecules to travel through the membrane
Two type of transport proteins - channel and carrier proteins
Carrier proteins change shape to transport substance
Each transport protein is specific to particular ion or molecule
Roles of Cholesterol on the cell surface membrane
Increases fluidity membrane at low temp so it stops it becoming rigid this occurs by stopping phospholipid tails packing too closely together
Decreases fluidity of membrane at high temp by stabilising membrane this occurs by cholesterol binding to tails of phospholipid which causes phospholipid packing closely together
Cholesterol increases the mechanical strength and stability
Describe the phospholipid of membranes
Forms a bilateral which acts as a barriers to most water soluble substances ensuring water soluble molecules cannot leak out of cells and unwanted water soluble cannot get in
They can be chemically modified to act as signallling molecules moving within belayer to activists other molecules
Phospholipid I layer composed of two layers of phospholipid hydrophobic tails face inwards hydrophilic head outwards
What factors affect membrane structure and permeability
The permeability of cell membrane is affected by different factors such as temperature and solvent concentration
How does temperature affect membrane structure and permeability
Proteins and lipids affect by temperature
As temp increases- lipids become more fluid this reduces the effectiveness of the cell membrane as a barrier to polar molecules
Temperature can effect the proteins leading them to denature distrusting the-membranes structure
How does solvent concentration affect membrane structure and permeability
Organic solvents can increase cell membrane e permeability as they dissolve the lipids in the membrane causing membrane to lose its structure