Cell surface protein (MHC I present on all nucleated cells NOT mature RBCs) Flashcards

1
Q

T cells

A

TCR (binds antigen-MHC complex)

CD3 (associated with TCR for signal transduction)

CD28 (binds B7 on APC)

CXCR4/CCR5 (co-receptors for HIV)

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2
Q

Helper T cells

A

CD4, CD40 L

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3
Q

Cytotoxic T cells

A

CD8

CXCR4/ CCR5

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4
Q

Regulatory T cells

A

CD3/CD4/ CD25/ FOXP3

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5
Q

B cells

A

Ig (binds antigen)

CD19, CD20, CD21 (receptor for EBV), CD40

MHC II, B7

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6
Q

Macrophages

A

CD14 (receptor for PAMPs, eg, LPS), CD40

CCR5

MHC II, B7 (CD80/86)

Fc and C3b receptors (enhanced phagocytosis)

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7
Q

NK cells

A

CD16 (binds Fc of IgG)

CD56 (unique marker for NK)

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8
Q

Hematopoietic stem

cells

A

CD34

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