Cell Transport Flashcards
(20 cards)
passive transport
diffusion of a substances across a membrane with NO energy investment
- diffuse down the concentration gradient, high to low
- 3 types
Simple diffusion
- a type of passive transport
- through membrane with no transport or carrier protein necessary
- ex. O2, CO2, lipids
Osmosis
- passive transport
- diffusion of water
- water moves from [high]=> [low]; moves toward side with more solute
Facilitated diffusion
- for larger polar or charged molecules that can not pass through the membrane
- needs a transport protein, but still NO energy
- ex. glucose, Na+
Active transport
- requires energy
- moves against the concentration gradient using ATP hydrolysis
- use carrier proteins
Primary active transport
uses ATP directly
-ex. Na+/K+ pump
Secondary active transport (cotransport)
energy does not directly come from ATP, active transport of a solute INDIRECTLY drives transport of other substances
- diffusion of actively transported solute down its concentration gradient coupled with transport of 2nd substance against its own concentration gradient
ex. Proton pump uses ATP and indirectly powers the H+/sucrose cotransporter
Exocytosis
transport vesicles migrate to membrane, fuse with it, and release contents outside of the cell
-export products
Endocyctosis
cells take in macromolecules by forming vesicles from plasma membrance
Phagocytosis
Cell eating, engulfs a particle in a vacuole
-fuses with a lysosome to digest
pinocytosis
molecules dissolves in droplets are taken up; cell drinking= invagination
receptor-mediated endocytosis
bind specific solutes to receptors to trigger vesicle formation
-receptor proteins, receptors, molecules from extracellular fluid are transported in vesicles
Effects of cholesterol on fluidity
- at warm temperatures cholesterol restrains movement of phospholipids
- at cool temp it maintains fluidity by preventing tight packing
- acts as a buffer
peripheral proteins
bound to surface of the membrane
integral proteins
penetrate hydrophobic core
transmembrane proteins
integral proteins that span the membrane
Functions of membrane proteins
transport, enzymatic activity, signal transduction, cell-cell recognition, intercellular joining, attachment to cytoskeleton and extracellular matrix
transport proteins
allow passage of hydrophilic substances across membrane
aquaporines
channel proteins that facilitate passage of water molecules
carrier proteins
a type of transport protein, binds to molecules and changes shape to shuttle across membrane
-specific for substances to move