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Antibiotics > Cell Wall Synthesis Inhibitors > Flashcards

Cell Wall Synthesis Inhibitors Flashcards

1
Q

Name 6 classes of cell wall synthesis inhibitors

A
  1. Penicillin
  2. Cephalosporins
  3. B-lactam ring but not penicillin
  4. Glycopeptides
  5. TB drugs
  6. B. lactamase inhibitors (cannot work alone)
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2
Q

Name 2 penicillinase sensitive drugs

  1. Acid Sensitive
  2. Acid Resistant
A
  1. Sensitive: Penicillin G

2. Resistant: Penicillin V

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3
Q

Name 2 penicillinase resistant drugs

  1. Acid sensitive
  2. Acid resistant
A
  1. Sensitive: Methacillin

2. Resistant: Oxacillin

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4
Q

Name 4 penicillinase sensitive drugs that are effective against gram - rods

  1. Broad spectrum
  2. Extended spectrum
A

Broad spectrum: Ampicillin & amoxicillin

Extended spectrum: Tricarcilin & piperacillin

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5
Q

Which penicillins are effective against P. aeuroginosa

A

Tricarcilin

Piperacilin

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6
Q

Which of the 2 penicillinase sensitive drugs that are effective against gram - rods is acid stable

A

Ampicilin

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7
Q

Which of the 2 penicillinase sensitive drugs that are effective against gram - rods reaches high serum levels

A

Amoxicillin

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8
Q

What is the downside of the extended spectrum penicillin (Ticarcillin & piperacillin)?

A

Less effective against G+ cocci

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9
Q

What are the 3 differences between cephalosporins and penicillins?

A
  1. Dihydrothiazine ring instead of thiazolidine ring
  2. Penicillinase resistant
  3. Acid stable
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10
Q

Name 1st, 2nd and 3rd Cepholosporins

A
  1. Cefazolin
  2. Cefuroxime
  3. Ceftriaxone
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11
Q

Cefazolin is effective against?

A

+ cocci

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12
Q

Cefuroxime is effective against?

A
  • rods

Less effective against + cocci

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13
Q

Ceftriaxone is effective against?

A
  • rods

P. aeuroginosa

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14
Q

Name to antibiotics that have B-lactam rings but are not similare to pencilin

A

Aztreonam

Imipenenm

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15
Q

Aztreonam is a

A

Monobactam

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16
Q

Imipenem is a

A

Carbapenems

17
Q

Name 2 gylcopeptides

A
  1. Vancomycin

2. Bactracin

18
Q

Vancomycin is effective against

A

Vancomycin

19
Q

Bactracin is applied

A

Topically

20
Q

Name 1 TB drug that is a cell wall inhibitor

A

Cycloserine

21
Q

Name 2 B-lactamase inhibitors

A
  1. clavunic acid

2. Sulbactam

22
Q

All cell wall inhibitors are STATIC or CIDAL

A

CIDAL

Antibiotics (8 decks)

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