CELLULAR ADAPTIONS Flashcards

1
Q

Dicrease in amount of tissue or Organ, and they undergo reduction in mass due to decrease in size & number of cells

A

ATROPHY

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2
Q

sample atrophy in physiologic

A
  1. postpartum uterine
  2. mammary gland involution
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3
Q

sample of atrophy in pathologic

A
  1. Disease atrophy
  2. denervation of atrophy
    3.persistent cell injury
  3. loss of hormonal stimulation
  4. aging
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4
Q

Mechanism and Biochemistry of atrophy

A

CATABOLIC PROCESS exeeds ANABOLIC PROCESS

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5
Q

in atrophy organelles are removed by?

A

AUTOPHAGOCYTOSIS

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6
Q

sequential mobilization in atrophy

A
  1. SUBCATENOUS FAT- first to use
  2. VISCERAL FAT- second to use
  3. BONE MARROW
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7
Q

this muscle are preseved at the expense of other muscle for locomotion

A

POSTURAL MUSCLE eg. supraspinatus m.

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8
Q

“increase size of an organs” due to increase in cell size without cellular proliferation

A

HYPERTROPHY

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9
Q

this muscle has remarkable capacity to undergo hypertrophy.

A

CARDIAC M. & SKELETAL M.

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10
Q

example of hypertrophy in response to work load:

A
  1. physiology- eg. EXCERCISE
  2. pathology- eg. enlargement of MYOCARDIAL FIBERS
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11
Q

example of hypertrophy in response to trophic signal.

A
  1. physiologic- uterus and mammary gland
  2. pathologic- MYOCARDIAL HYPERTROPHY
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12
Q

Mechanism and Biochemistry of hypertrophy:

A

ANBOLIC process exceeds CATABOLIC PROCESS

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13
Q

Gross: of hyopertrophy:

A

Tissue & organs INCREASE IN SIZE & WEIGHT NOT IN NUMBERS

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14
Q

Microscopic anatomy: of hypertrophy:

A

CELLULAR ENLARGEMENT due to increase of number in size and organelle size.

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15
Q

define as an increase in” number of cells” cause an increase in orgam or tissue mass

A

HYPERPLASIA

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16
Q
A