Cellular Fluid

Question 1

Total body water is how many litre? How much for icf and for ecf

Answer 1

42L
2/3 of 42L = 28 L is intracellular
1/3 of 42L = 14 L is extracellular

Question 2

What is transcellular fluid?

Answer 2

Is a special type of ecf arround 1-2 litre found as pleural fluid pericardial fluid synovial fluid intraoccular fluid

Question 3

Lean body mass?
How much water is present in 100 ml of lean body mass

Answer 3

Lbm= Body mass - (adipose tissue fat + non adipose tissue fat + bone mass)
70ml/100ml lbm

Question 4

Stewart hamilton method and its equations

Answer 4

Indicators used to determine the volume of fluid
Volume of fluid in human body = (amount of indicator injected - amt of indicator excreted) / concentration of indicator

Question 5

What are the indicators used for measurement of
TBW
ECF
PLASMA
BLOOD VOLUME

Answer 5

TBW: radioactive water , deuterium oxide , tritium oxide
ECF : inulin (most common ) mannitol sucrose ,sodium thiosulphate
Plasma: radio labelled albumin, evan blue dye ( does not cross plasma membrane)
Blood vol: chromium tagged RBC

Question 6

How calculate blood volume?

Answer 6

BV = plasma volume/ 1-hematocrit

Question 7

Most dominant ECF CATION and ANION also ICF cation and anion and ph of ecf and icf

Answer 7

ECF
CATION : Na+
ANION : CL -
Since ecf is good conductor of electricity because it contains NaCl (common salt)
ICF
CATION : K+ MG 2+
ANION : phosphate , protein
Ecf 7.4
ICF 7

Question 8

Plasma osmolarity is how much and what is majorly and minorly contributed

Answer 8

300 mosm/L
270 mosm/L by Na
0.75 mosm/L by protein aa concentration is low and high molecular weight

Question 9

Darrow yannet diagram ?
Xaxis
y axis

Answer 9

Alteration in volumes and osmolarity pf ecf and icf
X volume 2/3 icf + 1/3 ecf
Y osmolarity
Solid line normal
Dotted line altered

Question 10

What changes in ecf and icf volumes and osmolarity when
1) addition of isotonic solution (0.9% nacl) treatment of shock)
2) loss of isotonic solution ( diarrhoea)
3)addition of hypertonic solution (excess intake of salt lead to develop ht)
4) symptom of inappropriate secretion of ADH HORMONE (siadh) gain pf water

Answer 10

1)ecf volume increases others remain same
2)ecf volume decreases others remain same
3)ecf volume increases
Icf volume decreases
Ecf osmolarity increases
Icf osmolarity increases
4)both volume increases
Both osmolarity decreases