What cell of the CNS reacts most to trauma?
What is the neuron's response to acute injury, typically blood loss?How about chronic issues?
acute injury - red neurons
chronic injury - "degeneration" - really just drop out
What is an axonal reaction?
It's what happens to the cell body when an axon is severed - it basically just gets huge.
What are axonal spheroids and when do they occur?
These are spheridcal balls of protein that form within the axon itself - triggered by injury, but also just normal aging
What inclusion bodies will you see in herpes infections?
What inclusion bodies will you see in a rabies infection?
What is the neurofibrillary tangle made of in AD?
What are the 4 general reactions of astrocytes to injury?
What is gliosis?
It's proliferation of the astrocytes - trying to reform the general structure of the brain
What is gemistocytosis?
WHen the astrocytes send off really thick processes and look kinda big and juicy
What inclusion body might you see in an astrocyte post trauma?
What is corpora amylacea?
It's changes in the astrocyte such that it's bigger, rounder- almost like a pearl. It's a degenerative change you'll see in aging - doesn't really mean anything
How will microglia react to trauma like an infection or foreign body?
they'll proliferate and form a microglial nodule around the invader