Cementum Flashcards
(34 cards)
On wet - weight basis cementum is :
65% inorganic
23% organic
12% water 💦
By volume it contains
45% inorganic
33% organic
22% water 💦
Principal inorganic component is :
Hydroxyopatite crystal
Principal inorganic component is :
Hydroxyopatite crystal
Hydroxyopatite crystals are :
✓ 55nm wide and 8nm thick
✓other forms of Ca at higher levels in enamel and dentin
Fluoride levels higher in ?
Acellular than in cellular cementum
Fluoride levels higher in ?
Acellular than in cellular cementum
Organic matrix is of primarily?
Type I collagen ( III , V ,VI , XII also found in small quantities )
Fluoride levels in cementum are :
Higher than any of other mineralized tissues
Cementum - derived attachment protein ( CAP ) is ?
✓56 KDA or 65 KDA
✓Collagenous protein in cementum
✓Promote attachment of mesenchymal cells to extracellular matrix
Cap is present in
Matrix of mature cementum and in cementoblast ( not in bone )
It may be a marker to differentiate Bond and cementum?
CAP
Cementum is rich in GAGS , predominantly :
chondroitin sulphate
GAGS located around ?
Lacunae of cementum
( Dermatan sulphate and hyaluronan ) Can be found
Among the proteoglycans found in cementum are:
Lumican / versican / decorin/ fibromodulin / biglycan
Proteoglycan are located in ?
Peripheries of lacunae and canaliculi
Non- collagenous elements which are found are ?
✓Sialoproteins/ dentin sialoproteins/ fibronectin/ tenascin/osteopontin and other cementum- specific elements involved in PDL reattachment or mineralization
✓Such molecules contain well recognized addition domain arginine-glycine- aspartic acid that target specific integrin receptors on cells
Sialoproteins located in :
Cementum matrix
Osteopontin present in ?
Incremental lines
Which zones may be more highly calcified than dentine
Acellular zones
Which zones may be more highly calcified than dentine
Acellular zones
Cellular cementum 🤫
✓ contain cells ( cementocytes )
✓found mainly in the apical area overlying the acellular cementum
✓ formed after acellular cementum
✓ Also known as secondary cementum
✓ Found in interradicular areas
✓Faster rate of matrix formation
✓ As it develops , the formative cells become embedded in tissues as cementocytes
✓ precementum layer present ✅
✓more widely spaced incremental lines , thicker and more irregular
Acellular cementum
✓doesnot contain cells ( cementocytes )
✓Being formed first , it is known as primary cementum
✓Acellular cementum Is relatively structureless
✓in the outer region off radicular dentin the granular layer ( of Tomes ) can be seen outside, the hyaline layer
✓A dark line may be discerned / observed between the hyaline layer and acellular cementum that is patchily present at this position called as afibrillar cementum
The arrangement at the apical region of root is a layer of cementum overlying ?
Acellular cementum