Central-Acting Alpha Agonsists

Question 1

Which receptor does Clonidine stimulate?

Answer 1

It is a selective alpha 2-adrenergic agonist

Question 2

What does Alpha 2 drugs do?

Answer 2

It decreases release of norepinephrine, leading to vasodilation or decrease in blood pressure

Question 3

What happens to Methyldopa when ingested?

Answer 3

It is converted to methylnorepinephrine, which is an alpha2-adrenergic agonist. Thus, causing vasodilation and a reduction in blood pressure

Question 4

What are the side effects of these drugs if taken in increased doses or the drug is nonselective?

Answer 4

Hypertension, tachycardia, palpitations, restlessness, tremors, dysrhythmias, dizziness, urinary retention, nausea, vomiting, dyspnea, and pulmonary edema

Question 5

What is the trade name of Clonidine?

Answer 5

Catapres

Question 6

What is the trade name of Methyldopa?

Answer 6

Aldomet

Question 7

What is the generic name of Catapres?

Answer 7

Clonidine

Question 8

What is the generic name of Aldomet?

Answer 8

Methyldopa