Central Dogma, Gene Structure & Expression

Question 1

proteome

Answer 1

The collection of all proteins in a cell, tissue, or organism at a particular time.

Question 2

Messenger RNA (mRNA) synthesized from the DNA template through….

Answer 2

transcription

Question 3

nonsense mutation

Answer 3

a point mutation that results in a premature stop codon

Question 4

missense mutation

Answer 4

a point mutation that does not cause a stop codon, frequently results in amino acid change (non-synonymous changes). However may also cause synonymous change

Question 5

frameshift mutation

Answer 5

base deletion
the translational reading frame is altered for all subsequent codons

vs inframe mutation

Question 6

inframe mutation

Answer 6

the reading frame of the gene is preserved and not disrupted

vs frameshift mutation

Question 7

splice site mutations

Answer 7

Intronic mutations. Can lead to intronic retention or truncated
exon. May cause frameshifts or premature termination codon