Central Nervous System Flashcards
(44 cards)
- The central nervous system (CNS) is
- Neurons outside the CNS make up
- Most neurons are in
- CNS and PNS have cells called
- The CNS contains ventricles filled with
- Brain and Spinal Cord
- Peripheral Nervous System
- CNS
- CNS and PNS also have cells called glia, which support and protect neurons, and are about as numerous.
- The CNS contains ventricles filled with
cerebrospinal fluid
peripheral nervous system:
includes,
comprises of 2 systems x and y.
Part of y system is the
- The peripheral nervous system, or PNS, includes all neurons, and parts of neurons, outside the CNS.
- The PNS comprises the somatic nervous system, for controlling voluntary action via skeletal muscle, and the autonomic nervous
system, for visceral functions such as heart rate and breathing. - Part of the autonomic system is the enteric nervous system, which controls digestion and movements of the gut. It gets input from spinal cord, but can also work independently.
Gray Matter & arrangements,
White Matter &arrangements,
clusters called in the PNS
- Gray matter consists of nerve cell bodies, unmyelinated axons, and dendrites. The cell bodies are arranged either in layers (in parts
of the brain) or in clusters called nuclei - White matter consists of myelinated axons running in bundles called tracts.
- In the peripheral nervous system, clusters of neurons are called ganglia (singular: ganglion), and bundles of axons are nerves.
CNS and energy
1. The brain has just how much % of the body’s mass and consumes how much energy
2. how much glucose does the brain consume
3. how does the CNS save energy
a) Neurons communicate with each other by
b) The energy supply to the CNS can support
- The CNS saves energy by limiting communication between neurons
- Neurons communicate with each other by sending action potentials (spikes) down their axons, but those action potentials take a lot
of energy. - The energy supply to the CNS can support only a low rate of firing, e.g. in cortex it permits an average rate per cell of just one spike every 6 s. At any moment, only ~4% of your neurons are firing
Spinal Cord:
1. How many segments each with what
2. Each spinal nerve has a x which carries – signals. The — contains the — of the neurons carrying these signals
3. The ventral root
4. what is in the middle of the cord
- The spinal cord has 31 segments, each with a pair of spinal nerves
- Each spinal nerve has a dorsal root, which carries afferent (i.e. incoming, sensory) signals. The dorsal root ganglion contains the cell bodies of the neurons carrying these signals
- The ventral root carries efferent (i.e. outgoing) signals from the CNS to the body, including motor signals (i.e. to skeletal muscles)
- gray matter. the middle of the cord has a butterfly shape, with a dorsal and a ventral horn on each side
- The gray matter of the spinal cord consists of
- sensory nuclei: somatix and visceral
- Efferent nuclei: autonomic and motor
- The gray matter consists of sensory and motor nuclei
- Sensory nuclei are in the dorsal horn because sensory signals arrive on the dorsal root. Somatic sensory nuclei get signals from skin; visceral sensory nuclei get signals from the viscera (internal organs).
- Efferent nuclei are ventral. Autonomic efferent nuclei send commands to glands and smooth muscle; motor nuclei send commands to skeletal muscle
- White matter consists of
- Ascending tracts
- Descending tracts
- Proprispinal tracts
- White matter consists of axon tract
- Ascending tracts (green) carry sensory signals to the brain. They are mainly dorsal, because sensory signals arrive at the dorsal horn.
- Descending tracts (pale blue) carry signals from the brain. They are mainly ventral, where outgoing signals leave the CNS.
- Propriospinal tracts (not shown), stay in the spinal cord.
- 6 major divisions of the brain
- what make up the brain stem
- what is the brain stem
- what arises from the brain stem
- Cerebrum, Diencephalon, Midbrain, Pons, Medulla, Cerebellum
- Medulla, pons, and midbrain make up
the brain stem - The brain stem is the main control center for many autonomic functions and reflexes, such as breathing, swallowing, vomiting, and
regulating blood pressure. - Cranial nerves III–X and XII arise from the brain stem
- what are cranial nerves
- what are the parts of diencephalon and what do they do
- Cranial nerves are ones that enter or leave the brain rather than the spinal cord
- The diencephalon is the thalamus, hypothalamus, pituitary and pineal
a) The thalamus processes information going to and from the cerebral cortex.
b) The hypothalamus regulates behavioral drives, and endocrine and autonomic homeostasis.
c) Pituitary and pineal secrete hormones
- The cerebrum has x connected by
- The cerebral gray matter includes
- Corpus callosum is
- cerebral lateralization
- Each hemisphere has x lobes and what are they
- Each hemisphere also has a –, which is part of the —system
- The cerebrum has 2 hemispheres connected by the corpus callosum
- The cerebral gray matter includes the outer layer called the cortex, the limbic system (shown in a later slide), and the basal ganglia (which help control movement).
- Corpus callosum is a large bundle of myelinated axons
- The 2 hemispheres’ functions differ, i.e. we have cerebral lateralization
- Each hemisphere has 4 lobes: Frontal, Temporal, Parietal, Occipital, Temporal
- Each hemisphere also has a cingulate gyrus, which is part of the limbic system
- The limbic system is
- it includes
- it is concerned with
- The limbic system is an evolutionarily old group of brain regions
- It includes the cingulate gyrus, amygdala, and hippocampus
- It is concerned with motivation, emotion, and memory, e.g. monkeys with amygdala lesions, unlike normal monkeys, are not
frightened of snakes
- Every sensory system begins with
receptors
- what are receptors
- in some senory systems receptors are x and in other they are y
- receptor potential
- Every type of receptor cell has an
- These are cells which convert stimuli (e.g. light, sound) into electrical signals. The conversion is called transduction
- In some sensory systems (such as vision) the receptor cells are neurons; in others (such as hearing) they are non-neuronal epithelial cells.
- A receptor cell converts stimulus energy into a graded change in membrane potential called a receptor potential. The receptor may then release neurotransmitter to affect a neuron. If the receptor is itself a neuron, it may fire action potentials
- Every type of receptor cell has an adequate stimulus
- what is adequate stimulus
- 4 times of adequate stimuli
- what is a receptor threshold
- perceptual threshold
,
- Its adequate stimulus is the form of energy to which it is most responsive, e.g. thermoreceptors respond most sensitively to temperature.
- a) Chemoreceptors respond to specific molecules or ions, e.g. to glucose, or oxygen, or H
b) Mechanoreceptors respond to mechanical energy such as pressure, vibration, gravity, and sound.
c) Thermoreceptors respond to temperature.
d) Photoreceptors respond to light. - Any receptor has a receptor threshold — the weakest stimulus that will cause a response in the receptor.
- The perceptual threshold is different; it is the weakest stimulus that will cause a conscious perception in the organism, e.g. it takes ~40 odorant molecules for you to perceive a smell.
many receptors also respond to other forms of energy as well
- primary sensory neurons
- series of neurons
- convergence
- The first neurons in the system (either the receptors or the cells immediately downstream) are called primary sensory neurons
- Primary sensory neurons synapse onto secondary sensory neurons, and these synapse onto tertiaries, and so on.
- At each stage, many presynaptic cells may contact any one postsynaptic cell. This convergence allows secondary and higher neurons to combine data from many receptors
Sensory neurons carry information about many
aspects of the stimulus
- stimulus modality
- Sensory systems indicate modality by
- population coding of intensity.
- frequency coding.
- Both population coding and frequency coding
- One aspect is the stimulus modality, i.e. whether it is a light, a sound, a touch, etc.
- Sensory systems indicate modality by labeled lines, meaning that the modality is revealed by which axons carry the signal, e.g. activity on neurons in the visual pathway means light; activity on neurons in
the auditory pathway means sound. - Stronger stimuli may activate more neurons. This way of representing stimulus intensity, by the number of active neurons, is called population coding of intensity
- Stronger stimuli may make the individual neurons fire at a faster rate. This is frequency coding
- Both mechanisms may operate together: a stronger stimulus may increase the firing rates of neurons and also cause more neurons to be active.
Receptors and neurons have dynamics
- their activities may depend on 2 things (example)
- Phasic
- Tonic
- Phasic-tonic
2-4 are types of dynamics
- their activities may depend not only on the stimulus right now, but on how it changes through time. e.g. when a stimulus suddenly increases or decreases, many
receptors and neurons respond briefly and then fall silent again. So these cells signal changes in stimuli, not steady levels - Phasic cells respond briefly to any change and then cease firing. many retinal cells are phasic (report changes in your visual world, as when something move)
- Tonic cells maintain their activity when the stimulus is not changing, signalling its present level
- Phasic-tonic cells react to change but don’t return all the way to zero firing when the stimulus is constant, so they also carry information about its steady level.
making communication more efficient
- what cells make communication more effeciant
- temporal changes.
- spatial changes
- Sensory systems accentuate edges by
- Phasic signals make communication more efficient because it is more efficient to report changes than to repeat similar messages over and over.
- These kinds of changes through time, between one moment and the next, are called temporal changes.
- It is also efficient to report spatial changes. Spatial changes are differences between neighboring regions in space, e.g. neighboring patches of retina or skin.Spatial change is also called contrast, and locations where there is strong contrast are called edges.
- Sensory systems accentuate edges by lateral inhibition
- Lateral inhibition means that
use example diagrams
Lateral inhibition means that cells inhibit their neighbors, or they inhibit the cells their neighbors excite.
- Most sensory pathways run via
- Most pathways run through —, which is near —-, out to the s—- on the—
- what is the exception
- Equilibrium pathways project mainly
- Sensory processing is
- Most sensory pathways run via thalamus to cortex
- Most pathways run through thalamus, which is near the center of the brain, out to the sensory cortices on the surface of the cerebrum
- Olfactory (smell) pathways are an exception: they don’t project via thalamus.
- Equilibrium pathways project mainly to cerebellum
- Sensory processing is inference
a) Our senses evolved to guide our behavior: A big part of this guidance is
deducing what is going on around us, e.g. identifying things and so the brain has to infer.
b) Because it has to guess, the brain can be fooled: your brain produces an interpetation that is more likely
c) The brain mistrusts coincidences
- The eye is divided into 2 chambers by
- the lens is
- the lens is suspended by
- what is infront of the lens and what is it filled with
- behind the lens is, what is is filled with
- The eye is divided into 2 chambers by the lens
- The lens is a transparent disk that focuses light. It is suspended by ligaments called zonules
- In front of the lens is the anterior chamber, filled with aqueous humor, a plasma-like fluid.
- Behind is the vitreous chamber, filled with the vitreous body, a clear jelly that helps maintain the eyeball’s shape.
- what is the cornea
- what is the retina
- what is the pupil
a) what can the pupil do
b) pupil size is controlled by
c) what happens to the pupil in bright/dark light
d) the pupil also controls
- Light enters the eye through the cornea. The cornea is a transparent bulge at the front of the eye, continuous with the white of the eye, or sclera — the outer wall of the eyeball.
- Cornea and lens focus light on the retina, the inner lining of the eye that contains the photoreceptors.
- Light passes from the cornea to the lens through a hole in the iris called the pupil.
a) The pupil can change size
b) Pupil size is controlled by smooth muscles in the iris
c) Bright Light: pupils constrict (shrink) to 1.5 mm across, reducing the amount of light reaching the lens and parasympathetic signals from the brain contract the
ring-shaped pupillary constrictor muscle, shrinking the pupil.
Dark: In the dark they dilate (enlarge)to 8 mm, ~20 times bigger in area, to let in more light. In the dark, sympathetic signals contract the radial pupillary dilator muscle of the iris, dilating the pupil.
d) The pupil helps to focus light. The pupil also controls depth of field. When the pupil is tightly constricted, we have full depth of field, i.e. everything we see is equally in focus. When the pupil is tightly constricted, we have full depth of field, i.e.
everything we see is equally in focus
- Refraction
- Light bends when
- our corneas are made of – They bend light strongly because —
- Light is refracted by both the – and –
- The cornea is responsible for — of the eye’s refraction, and the lens for just —
- allows us to get a retinal image that is both bright and in focus
- Light bends when it enters a medium with a different refractive index
- our corneas are made of clear collagen. They bend light strongly because there is a big difference between the refractive indices of air and collagen.
- Light is refracted by both the cornea and the lens
- The cornea is responsible for 2/3 of the eye’s refraction, and the lens for just 1/3.
- The lens is made of
- lens is a mesh of – cells without –, packed with – and zippered together in – for –. It has no — but absorbs nutrients from –
- The lens of the eye is x. A A x lens is — in the middle and – at the edges. It
makes–.
- The lens is made of clear cells
- It is a mesh of long (12 mm) cells without nuclei, packed with clear proteins called crystallins, and “zippered” together in concentric layers for flexibility. It has no blood supply, but absorbs nutrients from the aqueous humor.
- The lens of the eye is convex. A convex lens is fatter in the middle and thinner at the edges. It makes light rays converge to a focal point. Another example of a convex lens is a magnifying glass