Central Nervous System Drugs Flashcards
(20 cards)
Study of drugs that alter processes controlled by the nervous system.
Neuropharmacology
Conducting an action potential down the axon of the neuron
Axonal Conduction
Process by which information is carried across the gap between neuron and postsynaptic cell
Synaptic Transmission
A network of blood vessels and tissue that is made up of closely spaced cells and helps keep harmful substances from reaching the brain.
Blood Brain Barrier
Stimulate the release of NE and DA from the brain and SNS
Amphetamines
Treatment of respiratory depression caused by drug overdose and COPD
Doxapram
Slowly progressive neurodegenerative disorder characterized by tremor, rigidity, postural instability and slowed movement
Parkinson’s disease
What are the partial focal seizures
Carbamazepine
Gabapentin
Lamotrigine
Tiagabine
Topiramate
Most commonly prescribed anticonvulsant drug
Phenytoin
Effective against partial seizures and generalized tonic-clonic seizures but not absence seizures
Phenobarbital
Cornerstone of epilepsy therapy
Carbamazepine
Slow down the body and brain’s functions.
Benzodiazepine
Bind to a carrier protein and act a receptor resulting in increased GABA in the brain
Gabapentin
Defined as involuntary contraction of a muscle or muscle group
Muscle spasm
Most effective for spasticity of cerebral origin (cerebral palsy, MS, spinal cord injury, stroke)
Dantrolene Sodium
The biological process by which a neuron communicates with a target cell across a synapse.
Synaptic transmission
5 STEPS OF SYNAPTIC TRANSMISSION
-Synthesis of neurotransmitter
-Storage of vesicle
-Release of neurotransmitter from the terminal neuron
-Action and receptor
-Termination of transmission
Drugs that block receptors
Anticholinergic Agents
Directly/Indirectly activation of dopamine receptors
Dopaminergic drugs
Group of disorders characterized by excessive excitability of neurons in the CNS
Epilepsy