Central Nervous System drugs Flashcards
(20 cards)
NEUROPHARMACOLOGY
Study of drugs that alter processes controlled by the nervous system
What is CNS DRUGS
Used for psychiatric disorders, suppression of seizures, relief of pain,
production of anesthesia
What is BLOOD BRAIN
BARRIER
Impedes the entry of drugs into the brain
KINDS OF CNS STIMULANTS
ADHD
NARCOLEPSY
KINDS OF CNS STIMULANTS
ADHD
NARCOLEPSY
What is AMPHETAMINES
Stimulate the release of NE and DA from the brain and SNS
What does PARKINSON’S DISEASE affects?
the extrapyramidal system
which influences movement
What is Dopaminergic drugs
Directly/ indirectly cause
activation of dopamine
receptors
What is Anticholinergic Agents
drugs that block receptors
for ACh
What is EPILEPSY
Group of disorders characterized by excessive excitability of neurons in the CNS
What is PARTIAL SEIZURES
Excitation undergoes limited spread from the focus to adjacent cortical areas
What is GENERALIZED SEIZURES
Excitation spreads widely throughout both hemispheres of the brain
Drugs for Partial Focal
Seizures
Carbamazepine
Gabapentin
Lamotrigine
Tiagabine
Topiramate
Drugs for Absent Seizures
- Succinimides
- Ethosuximide
- Methsuximide
- Phensuximide - Valproic Acid
- Zosinamide
PHENYTOIN
most commonly prescribed
anticonvulsant drug, Stabilize nerve cells to keep them from getting overexcited by increasing efflux or decreasing influx of sodium ions
MUSCLE SPASM
- Defined as involuntary
contraction of a muscle or muscle group - Often painful and decreases level of functioning
CLASSES OF MUSCLE SPASM
Centrally-acting
Direct-acting
NEUROMUSCULAR
BLOCKING DRUGS
Relax skeletal muscles by
disrupting the transmission of nerve Impulses at the motor end plate
ABSTINENCE SYNDROME
Withdrawing from a substance that has
the potential to cause addiction can
cause abstinence syndrome
OPIOID ADDICTION
Characteristic withdrawal syndrome occurs within 1 hr. to several days after cessation of substance use.