Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmocology > Central Nervous System Pharm > Flashcards

Central Nervous System Pharm Flashcards

1
Q

What are Typical Antipsychotics? Examples?

A

Dopamine Antagonist. Phenothiazines, Haloperidol, Thiothixene.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is Chloropromazine?

A

Typical Antipsychotic.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is Haloperidol?

A

Typical Antipsychotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What can Typical Antipsychotics cause?

A

Extrapyramidal motor effects like Dyskinesias and parkinson like symptoms.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are Atypical Antipsychotics?

A

2nd Generation Dopamine Antagonist with less Dyskinesias.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is Clozapine?

A

Atypical Antipsychotic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is Neuroleptic Malignant Symdrome?

A

Neurological disorder that is an adverse reaction to antipsychotic.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are other adverse effects of antipsychotic use?

A

Antimuscarinic symptoms: Constipation, dry mouth,..
Orthostatic Hypotension
Convulstions, Photosensitivity, Cardiac arrythmias, Galactorrhea.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is unipolar depression?

A

Mood changes in one direction.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is bipolar depression?

A

Less common, Oscillates between manic and depressive.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the types of Monoamine Uptake inhibitors and their drug examples?

A
  1. Trycyclic Antidepressants (TCAs), Amitriptyline.
  2. Selective Serotonin reuptake inhibitors (SSRIs), Prozac (Fluoxetine).
  3. Mixed 5-HT and NE reuptake inhibitors (SNRIs), Venlafaxine, Duloxetine,
  4. Norephinephrine reuptake inhibitors, Bupropion.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is a Monoamine Oxidase inhibitor (MAOIs) and drug example? What is the warning with these drugs??

A

Antidepressant drug. Phenelzine.

*These should not be used with other antidepressant drugs or with autonomic drugs that release catecholamines or serotonin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are some other common antidepressant drugs and their method?

A
  1. Mirtazapine, Monomaine receptor antagonist.
  2. Trazodone, potentiate 5HT activity.
  3. St John’s wort, weak monomine uptake inhibitor.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are some drugs that treat biopolar depression?

A

Lithium, Valproate, Olanzapine.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

WHAT DO GABA-A receptors do? Causes?

A

Activating or enhancing chloride channels. Sedative hypnotic.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the uses for sedative hypnotics?

A

Anti-anxiety, Panic disorder, Sedation, Anticonvulsants, Amnesia, Insomnia, Skeletal muscle relaxation.

17
Q

What do Benzodiazepines and Barbiturates do? Effect?

A

Enhance effect of native GABA-A receptors. Sedative Hypnotics.

18
Q

What are the Long acting, short acting, and intermediate acting subclasses of barbiturates with drug examples.

A
  1. Long: Phenobarbital
  2. Intermediate: Pentobarbital
  3. Thiopental
19
Q

What are Chloral Hydrates? Used for? Contraindications?

A

Sedative hypnotic similar to benzodiazepines. Sleep inducer, concious sedation. Can result in serious cardiac and other toxicities if dose not controlled.

20
Q

What is Zolpedem? Used for?

A

(Ambien) Acts on GABAA receptor B. Mainly treat insomnia.

21
Q

What is Buspirone?

A

Partial Agonist 5-HT1A, Sedative Hypnotic.

22
Q

What is Baclofen?

A

Agonist at GABA-B, sedative hypnotic.

23
Q

What is Ethanol?

A

Multiple target including GABA-A, Sedative Hypnotic.

24
Q

What is Flumazenil? What does it do?

A

GABA-A receptor antagonist, reverses sedation of drugs acting on BZ sites.

25
Q

What is phenobarbital? Mechanism?

A

Antiepileptic. GABA-A receptor modulator

26
Q

What is Phenytoin? Mechanism?

A

Antiepilieptic. Na+ Antagonist.

27
Q

What is Primidone? Mechanism?

A

Antiepileptic. Metabolized into phenobarbital and other active compounds.

28
Q

What is Carbamazepine used for? Mechaism?

A

Antiepileptic and bipolar. Na+ Antagonist.

29
Q

What is Gabapentin used for? Mechanism?

A

Antiepileptic. No known mechanism.

30
Q

What is Valproate used for? Mechanism?

A

Antiepileptic, Bipolar. GABA incrase and Block Na+ and Ca++.

31
Q

What is ethosuximide used for? Mechanism?

A

Antiepileptic. Block Ca++.

32
Q

What is Levodopa (L-Dopa) Used for? Mechanism?

A

Parkinsons. Transported past BBB, converted into dopamine.

33
Q

What is Carbidopa used for? Mechanism?

A

Parkinsons. Dopa decarboxylase inhibitor. Used to prevent L-Dopa being converted in periphery systems.

34
Q

What is Tolcapone used for? Mechainsm>

A

Parkinsons. Blocks catecholamine O-Methyl transferase, prevents breakdown of dopamine.

35
Q

What is Rasagaline and Selagiline used for? Mechaisms?

A
  1. Rasagaline: Parkinsons
  2. Selagiline: Parkinsons and depression.

Both block monoamine oxidase type B.

36
Q

What is Diphenhydramine used for in parkinsons?

A

(Benadryl) Treats side effects.

37
Q

What is Amantadine used for? Mechanism in parkinsons?

A

Used to treat flu. Blocks NMDA receptor.

38
Q

What is Benztropine used for? Mechanism in Parkinsons?

A

Anticholinergic drug, restoring cholinergic/dopaminergic balance.

Pharmocology (8 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions